Campbell Essential Biology (7th Edition)
7th Edition
ISBN: 9780134765037
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Chapter 12, Problem 12IMT
For each statement, identify which major theme is evident (the relationship of structure to function, information flow, pathways that transform energy and matter, interactions within biological systems, or evolution) and explain how the statement relates to the theme. If necessary, review the themes (see Chapter-1) and review the examples highlighted in blue in this chapter.
12. Studying whole genomes reveals how genes from one generation can affect the appearance of the next.
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Using the GeneEx Computer Simulation http://intro.bio.umb.edu/MOOC/jsGX/JsGenex_C2.html
Complete the following Question and upload a screenshot to this assignment with your unique gene shown. (Use the Snipping Tool to capture a screenshot- it is in the start button and search for snipping tool)
Design an entirely new gene that you have invented.
Using the new Gene Explorer, this gene should (you can make it more challenging if you like):
Produce a protein of at least five amino acids (including the N-terminal Met).
Contain at least one intron.
Tips
1.Use the “Enter New DNA Sequence” button and delete the starting sequence from the entry blank.
2.Type in a promoter, a little DNA, and a terminator; be sure your RNA is made.
3.Click on your gene and add the start codon, coding region, and stop codon; be
sure your protein is made. Type slowly so that the program can keep up.
4. Similarly, add an intron in the coding region and be sure your gene works
Bioinformatics is an interdisciplinary field that integrates knowledge of computer science
with mathematics and statistics to solve biological questions. Many bioinformatics tools
for gene prediction, homology modelling and such are available free online.
(1) What does BLAST stand for?
(ii)
Explain the function of BLAST.
Write and detail a complete all encompassing definition of a gene. Consider the morphology,
physiology, ecological, behavioral, etc. aspects of the gene. Discuss each part of the gene listed
in your definition. Is your definition of the gene as determined through complementation,
recombination, and mutation for prokaryotes directly applicable to eucaryotes? Why or why
not? What additional information must be taken into account?
Chapter 12 Solutions
Campbell Essential Biology (7th Edition)
Ch. 12 - Suppose you wish to create a large batch of the...Ch. 12 - A carrier that moves DNA from one cell to another,...Ch. 12 - Prob. 3SQCh. 12 - A paleontologist has recovered a bit of organic...Ch. 12 - Why do DNA fragments containing STR sites from...Ch. 12 - What feature of a DNA fragment causes it to move...Ch. 12 - After a gel electrophoresis procedure is run, the...Ch. 12 - Name the steps of the whole-genome shotgun method.Ch. 12 - Put the following steps of human gene therapy in...Ch. 12 - For each statement, identify which major theme is...
Ch. 12 - Prob. 11IMTCh. 12 - For each statement, identify which major theme is...Ch. 12 - Some scientists once joked that when the DNA...Ch. 12 - Interpreting Data When comparing genomes from...Ch. 12 - Listed below are 4 of the 13 genome sites used to...Ch. 12 - In the not-too-distant future, gene therapy may be...Ch. 12 - Today, it is fairly easy to make transgenic plants...Ch. 12 - 18. In October 2002, the government of the African...Ch. 12 - From 1977 to 2000, 12 convicts were executed in...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Identify the word or phrase that is the best match (some will remain blank). (Mouse Genome Informatics, GeneChip array, Confounding variable, 45,000, BLAST, 600, Aceview, BioGPS, SMART, minimize, 17, UCSC Genome Browser, External validity) A. Median number of copies of an mRNA in a cell B. Patterns and sizes of introns and exons C. H3K4me3 locations on chromosomes D. Each treatment given to a different litter of mice E. Find list of knockout mice for a gene D. Find similar proteins F. Random variation G. Tissue expression pattern of a gene H. The extent to which results can be extrapolatedarrow_forwarddescribe some of the key findings from the Human Genome Project so that you can picture in a general fashion how these 3 billion nucleotides are organized.arrow_forwardIn the space below, write the Central Dogma of molecular biology. Be sure to label the names of the processes.arrow_forward
- Give (3) three applications or uses of Human Genome Project and briefly explain each..arrow_forwardGive the scope of the following fields in Applied Genetics: Epigenetics Genomics Genetic Engineering Phylogenetics Metagenics take note that SCOPE is what I'm askingarrow_forwardThe Selfish Gene is a radical theory that argues that all living creatures are essentially vehicles for their genes- hence, we all are a “survival machine" for our genes. In the light of what you have learned about the molecular structure and function of the gene, is this perspective still relevant? Cite specific biological phenomena to prove your point. References:arrow_forward
- Discuss 3 influences/studies in Genetic and Biochemistry in relation to Molecular Biology.arrow_forwardThe College of Medicine of the University of the USA - Texas offers a double degree program on medicine and molecular biology. Once you complete the requirements of the said program, you will graduate as a Medical Doctor and a Doctor Philosophy in molecular medicine (MD- PhD). Once of the requirements of the said program is to publish a dissertion on molecular medicine. Suppose you are on your final year under the said program, you will discuss one biomelecular disorder. You will then propose possible ways on addressing the said disorder.arrow_forwardBeing able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…arrow_forward
- Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…arrow_forwardEssay: Answer the following questions in paragraph form. Create atlest 3-5 sentences each to support your answer. Base on your own opinion, what does genetics mean? What is its relationship to all living things? What is the connection of Genetics and DNA with each other? Are they related or not? Give your own opinion and you can also cite an example if needed. What is DNA, rDNA and mtDNA? Explain each function. What are the advantages and disadvantages of genetic engineering? If you were given the chance to genetically modify an organism, what would it be and what would you like to modify from that organism?arrow_forwardThe words “transcribe” and “translate” are more commonly associated with language and dialogue. For example, a court reporter may transcribe what was said during a trial, or a popular book may be translated from Spanish into English. Why are “transcription” and “translation” such good descriptors for these processes in molecular biology?arrow_forward
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