Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Textbook Question
Chapter 11, Problem 5TYK
Which of the following is a key difference between GPCRs and RTKs?
- a. GPCRs use cGMP, but RTKs use cAMP.
- b. GPCRs are membrane bound, but RTKs are found in the cytoplasm.
- c. GPCRs are common in animal cells, but RTKs are common in plant cells.
- d. GPCRs generally activate a single pathway, but RTKs may trigger many signal transduction pathways.
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A small number of cell surface receptors and low amounts of signals (ligands) can generate a large intracellular response as each step of the signal transduction pathway can be expanded by...
A. gene amplification, i.e. increasing the number of target genes.
B. enzyme-mediated signal amplification, e.g. phosphorylation cascades.
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D. ATP Synthase, e.g. by building proton (H+) gradients.
What is the function of Ras during tyrosine kinase cell signaling?
a. It activates the opening of channel-linked receptors.
b. It is an enzyme that synthesizes second messengers.
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d. It phosphorylates other enzymes as part of a pathway.
Which of the following statements regarding signaling in normal cells and cancer cells is false?
a. In normal cells, RTK transphosphorylation is strictly dependent on ligand binding. Ligand binding promotes a
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can be ligand-independent.
c. Cancer cells that have established several autocrine signaling loops have a poor prognosis, because these
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4
d. The extracellular ectodomains of all RTKS are highly conserved in primary sequence and structure.
e. RTKS have a hydrophilic extracellular ectodomain, and hydrophobic transmembrane domain, and a
hydrophilic cytoplasmic domain, which contains the catalytic portion of the protein.
Chapter 11 Solutions
Study Guide for Campbell Biology
Ch. 11 - How do plant hormones (often called plant growth...Ch. 11 - Prob. 2IQCh. 11 - Label the parts in the following diagram of an...Ch. 11 - Prob. 4IQCh. 11 - a. What does a protein kinase do? b. What is a...Ch. 11 - Prob. 6IQCh. 11 - Prob. 7IQCh. 11 - Prob. 8IQCh. 11 - a. What can one conclude from the fact that the...Ch. 11 - Prob. 1SYK
Ch. 11 - Briefly describe the three stages of cell...Ch. 11 - Some signaling pathways alter a proteins activity;...Ch. 11 - Prob. 4SYKCh. 11 - Prob. 1TYKCh. 11 - Steroid hormones a. bind to cell-surface...Ch. 11 - Prob. 3TYKCh. 11 - Prob. 4TYKCh. 11 - Which of the following is a key difference between...Ch. 11 - Many human diseases (including bacterial...Ch. 11 - Prob. 7TYKCh. 11 - If a protein is activated by the addition of a...Ch. 11 - Prob. 9TYKCh. 11 - Prob. 10TYKCh. 11 - From studying the effects of epinephrine on liver...Ch. 11 - You are a Ca2+ ion in a typical animal cell. Where...Ch. 11 - Which of the following molecules is incorrectly...Ch. 11 - Prob. 14TYKCh. 11 - Prob. 15TYK
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license