Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Textbook Question
Chapter 11, Problem 13TYK
Which of the following molecules is incorrectly matched with its description?
- a. scaffolding protein—large relay protein that may bind with several other relay proteins to increase the efficiency of a signaling pathway
- b. protein phosphatase—enzyme that transfers a phosphate group from ATP to a protein, causing a shape change that usually activates that protein
- c. adenylyl cyclase—enzyme attached to plasma membrane that converts ATP to cAMP in response to an extracellular signal
- d. phospholipase C—enzyme that may be activated by a G protein or receptor tyrosine kinase and cleaves a plasma-membrane phospholipid into the second messengers IP3 and DAG
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Chapter 11 Solutions
Study Guide for Campbell Biology
Ch. 11 - How do plant hormones (often called plant growth...Ch. 11 - Prob. 2IQCh. 11 - Label the parts in the following diagram of an...Ch. 11 - Prob. 4IQCh. 11 - a. What does a protein kinase do? b. What is a...Ch. 11 - Prob. 6IQCh. 11 - Prob. 7IQCh. 11 - Prob. 8IQCh. 11 - a. What can one conclude from the fact that the...Ch. 11 - Prob. 1SYK
Ch. 11 - Briefly describe the three stages of cell...Ch. 11 - Some signaling pathways alter a proteins activity;...Ch. 11 - Prob. 4SYKCh. 11 - Prob. 1TYKCh. 11 - Steroid hormones a. bind to cell-surface...Ch. 11 - Prob. 3TYKCh. 11 - Prob. 4TYKCh. 11 - Which of the following is a key difference between...Ch. 11 - Many human diseases (including bacterial...Ch. 11 - Prob. 7TYKCh. 11 - If a protein is activated by the addition of a...Ch. 11 - Prob. 9TYKCh. 11 - Prob. 10TYKCh. 11 - From studying the effects of epinephrine on liver...Ch. 11 - You are a Ca2+ ion in a typical animal cell. Where...Ch. 11 - Which of the following molecules is incorrectly...Ch. 11 - Prob. 14TYKCh. 11 - Prob. 15TYK
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- Which is true about signaling receptors? They are transmembrane proteins that have binding sites for extracellular activated proteinsto effect changes inside the cell. They are transmembrane proteins that have binding sites for extracellular DNA-binding proteins to effect changes inside the cell. They are transmembrane proteins that have binding sites for extracellular enzyme effectors to effect changes inside the cell. They are transmembrane proteins that have binding sites for extracellular messengers to effect changes inside the cell.arrow_forwardExplain the three stages of cell signaling. a. receptor b. transduction c. response. Attach imagesarrow_forwardWhat type of cell signaling receptor is depicted below a. Cytoplasmic Receptor b. Transmembrane Receptor c. Intracellular Receptor d. Nuclear Receptorarrow_forward
- Below is a diagram of the canonical Wnt signalling pathway. Numbers 1-7 refer to different molecules involved in the pathway. Numbers 1-7 on the diagram indicate molecules that are involved in the Wnt signalling pathway, but their names have not been given. Identify the missing components and write their names against the numbers 1-7 given below: 1. 2. 3. 4. 5. 6.arrow_forwardThe figure below illustrates a model of a signal transduction cascade, initiated by the bind- ing of a ligand to a membrane-bound receptor. ligand A partial model of a signal transduction pathway A inactivated molecules B -receptor protein A D activated molecule 1 Based on the figure, which of the following describes the most likely outcome of a mutation that changes the intracellular region of receptor protein A? activated molecule 2 activated molecule 3 The receptor will not activate molecule 1, but the activation of molecules 2 and 3 will continue at lower rates. Molecule 1 will not become activated, preventing the activation of molecules 2 and 3 and the subsequent cellular response. с The ligand will not be able to bind the membrane-bound receptor, preventing the signal transduction pathway from initiating. The ligand that binds to protein A will not enter the cell, preventing the cellular response from occurring.arrow_forwardWhich statement best describes how molecular complementarity enables specificity during a signaling event? The molecular shape of two molecules should have a small amount of complementarity. The molecular shape of two molecules should have a large amount of overall complementarity that involves weak interactions at multiple different sites. The molecular shape of two molecules should have a large amount of overall complementarity that involves strong interactions at multiple different sites. The molecular shape of two molecules should have a large amount of overall complementarity that involves covalent interactions at multiple different sites.arrow_forward
- A ligand binds to the extracellular portion of a receptor. Another ligand binds to an identical half of the same receptor. When this happens, the two halves come together and the intracellular portion adds phosphates from ATP to tyrosine amino acids it the receptor structure. This passage describes what kind of receptor? Select one: a. A G-protein coupled receptor b. A receptor tyrosine kinase c. A receptor tyrosine phosphatase d. A ligand-gated kinase channelarrow_forwardWhich of the following statements regarding signaling in normal cells and cancer cells is false? a. In normal cells, RTK transphosphorylation is strictly dependent on ligand binding. Ligand binding promotes a conformational change in the RTKS that is required for dimerization, and dimerization is required for transphosphorylation. b. Cancers cells that over-express RTK's can respond to tiny amounts of ligand, and in some instances signaling can be ligand-independent. c. Cancer cells that have established several autocrine signaling loops have a poor prognosis, because these cells have enabled multiple independent mitogenic signal transduction pathways. 4 d. The extracellular ectodomains of all RTKS are highly conserved in primary sequence and structure. e. RTKS have a hydrophilic extracellular ectodomain, and hydrophobic transmembrane domain, and a hydrophilic cytoplasmic domain, which contains the catalytic portion of the protein.arrow_forwardWhich of the following would be considered second messengers of a signaling pathway? Select one: a. A kinase enzyme b. A scaffolding protein holding three kinases c. Adenyl cyclase d. All answers are examples of second messengers e. A sugar like inositol f. Ligand gated channelarrow_forward
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