Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 3, Problem 9RQ
Summary Introduction
Interpretation:
The osmolarity of
Concept introduction:
The concentration of a solution that contributes to the osmotic pressure, which is expressed in osmoles of solute per liter of solution.
An osmole is defined as 1 mol of particles that contribute toward the osmotic pressure of the solution.
Osmolarity of a solution is obtained by multiplying the molarity with the number of osmoles produced by the solute of the solution.
It is donated by the unit osmole.
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This question also uses the same
experimental setup as in Questions 1 and 2
and the same modification of the attached
figure (Figure 2.5 of your textbook). The
modification is that the KCL solutions in the
middle panel are replaced with NaCl solutions
(1 mM on the left or inside and 10 mM on the
right or outside). Using the Nernst equation,
which is also shown below and described in
your textbook, what is the equilibrium
potential for Na+?
(A)
from
3
Inside
1 mM KO
-Voltmeter
V = 0
Outside
1 πιΜ KC1
Permeable to K'
No not flux of K
K* lon
(B) Initial canditions
Insido
10 mM KCI
-29 mV
+58 mV
Initially
V-0
+29 mV
. -58 mV
mir
Outside
1 αιΜ ΚΟ
Net flux of K*
from inside
to outside
G
At equilibrium
0
Vie-out-58 my
क।
Inside
Outside
10 mM KO
1 mM Ka
Flux of K* from trude to
outside bulanced by opposing
membrane potential
Membrane potential
V₁ (mv)
0
8
-116
100
(K¹ (MM)
10
Eion (mv) = 58/z* log
([ion]out /[ion]in)
Slope 58 my per
tenfold change in
K gradient
KLOST
Log K
I
0
Three proteins that facilitate the movement of phospholipidmolecules across a membrane are flippase, floppase, and_________________________.
What explains the 10,000 to 1 selectivity of the potassium channel for K+over Na+ ion?
Note: Instead of providing the actual answer from the textbook, I look forward for a precise and original answer for this question. At least no more than six sentences.
Chapter 3 Solutions
Biochemistry: The Molecular Basis of Life
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