Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 8, Problem 79P
A study was performed looking at the effect of physical activity on cognitive
Table 8.23 Mean difference from baseline (18-month score minus baseline score) among participants with mild cognitive impairment in the ADAS-Cog score*
*A negative change indicates improvement since high values on the testindicate worse cognitive function
What test can be performed to compare the mean change in the two groups at 18 months?
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Mental Health
A study was performed looking at the effect of physical activity on cognitive function among adults at high risk for Alzheimer's disease. There were 170 eligible subjects randomly assigned to either an exercise intervention (exercise group) or a control intervention (control group). The subjects were followed at 6-month intervals up to
18 months of follow-up. The primary assessment scale was the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog). The results at 18 months of follow-up among participants with mild cognitive impairment are given in the table below. (Let population 1 be the exercise group and population 2 be the control group.
Use exercise group control group.)
Mean difference from baseline (18-month score
minus baseline score) among participants with
mild cognitive impairment in the ADAS-Cog
score*
Mean change
95% CI
n
H₁:
Exercise group Control group
USE SALT
-0.37
(-1.37, 0.63)
48
-0.43
(-1.35, 0.49)
52
(a) What is the standard deviation of…
Callahan (2009) conducted a study to evaluate the effectiveness of physical exercise programs for individuals with chronic arthritis. Participants with doctor-diagnosed arthritis either received a Tai Chi course immediately or were placed in a control group to begin the course 8 weeks later. At the end of the 8-week period, self-reports of pain were obtained for both groups. Data similar to the results obtained in the study are shown in the following table.
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Chapter 8 Solutions
Fundamentals of Biostatistics
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