Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 8, Problem 19P
The drug diflunisal is used to treat mild to moderate pain due to osteoarthritis (OA) and rheumatoid arthritis (RA). The ocular effects of diflunisal had not been considered until a study was conducted on its effect on intraocular pressure in glaucoma patients who were already receiving maximum therapy for glaucoma [5].
Suppose the change (
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Overproduction of uric acid in the body can be an indication of cell breakdown. This may be an advance indication of illness such as gout, leukemia, or lymphoma. Over a period of months, anadult male patient has taken eight blood tests for uric acid. The mean concentration was ?̅= 5.35mg/dl. The distribution of uric acid in healthy adult males can be assumed to be normal, withσ = 1.85 mg/dl.a. Find a 90% confidence interval for the population mean concentration of uric acid in thispatient’s blood. What is the margin of error?b. Find a 99% confidence interval for the population mean concentration of uric acid in thispatient’s blood. What is the margin of error?c. Compare the margins of error for parts (a) and (b). As confidence levels increase, do marginsof error increase?
Overproduction of uric acid in the body can be an indication of cell breakdown. This may be an advance indication of illness such as gout, leukemia, or lymphoma. Over a period of months, an adult male patient has taken eight blood tests for uric acid. The mean concentration was = 3.5 mg/dl. The distribution of uric acid in healthy adult males can be assumed to be normal, with σ = 1.85 mg/dl.
Find a 95% confidence interval for the population mean concentration of uric acid in this patient’s blood. What is the margin of error?
What conditions are necessary for your calculations?
Interpret results in the context of this problem.
Sample Size Find the sample size necessary for a 95% confidence level with maximal margin of error E=1.10 for the mean concentration of uric acid in this patient’s blood.
Does the potency of drug reduce after one year in storage?
To test this, researchers plan to compare the average potency of a sample of recently produced bottles of the drug with the average potency of a sample of bottles of the drug that have been stored for a year.
They will test for evidence that the mean potency score for the fresh drug (µ1) is higher than the mean potency score for the stored drug (µ2).
Based on the information provided, which of the following sets of hypotheses is appropriate for the test?
Hint: We first cover inference for a difference in means in Section 6.4.
Select one:
a.H0: μ1 - μ2 ≤ 0, Ha: μ1 - μ2 = 0
b.H0: μ1 - μ2 = 0, Ha: μ1 - μ2 > 0
c.H0: μ1 - μ2 = 0, Ha: μ1 - μ2 < 0
d.H0: μ1 - μ2 = 0, Ha: μ1 - μ2 ≠ 0
Chapter 8 Solutions
Fundamentals of Biostatistics
Ch. 8 - Find the lower 2.5th percentile of an F...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...
Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - Refer to the data in Table 2.13. Table 2.13...Ch. 8 - Refer to the data in Table 2.13. What is the...Ch. 8 - Refer to the data in Table 2.13. Perform the...Ch. 8 - Refer to the data in Table 2.13. What is the...Ch. 8 - Refer to the data in Table 2.13. 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Prob. 69PCh. 8 - An experiment was conducted to examine the...Ch. 8 - An experiment was conducted to examine the...Ch. 8 - An experiment was conducted to examine the...Ch. 8 - Prob. 73PCh. 8 - Prob. 74PCh. 8 - Prob. 75PCh. 8 - Prob. 77PCh. 8 - A study was performed looking at the effect of...Ch. 8 - A study was performed looking at the effect of...Ch. 8 - A study was performed looking at the effect of...Ch. 8 - Prob. 81PCh. 8 - Prob. 82PCh. 8 - Prob. 83PCh. 8 - Tennis elbow is a painful condition that afflicts...Ch. 8 - Prob. 85PCh. 8 - Prob. 86PCh. 8 - Prob. 87PCh. 8 - Prob. 88PCh. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - Prob. 94PCh. 8 - Prob. 95PCh. 8 - Prob. 96PCh. 8 - Prob. 98PCh. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study is being planned to assess whether a...Ch. 8 - A study is being planned to assess whether a...Ch. 8 - Prob. 105PCh. 8 - Prob. 106PCh. 8 - Left ventricular mass (LVM) is an important risk...Ch. 8 - Left ventricular mass (LVM) is an important risk...Ch. 8 - Prob. 109PCh. 8 - Prob. 110PCh. 8 - Prob. 111PCh. 8 - A study sought to demonstrate that soy beans...Ch. 8 - Prob. 113PCh. 8 - A study sought to demonstrate that soy beans...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - The Diabetes Prevention Study was a randomized...Ch. 8 - Prob. 122PCh. 8 - Prob. 123PCh. 8 - Prob. 124PCh. 8 - Prob. 125PCh. 8 - Prob. 126PCh. 8 - 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