Biology: Concepts and Investigations
5th Edition
ISBN: 9781260259049
Author: Hoefnagels
Publisher: MCG
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Chapter 7.6, Problem 2MC
Summary Introduction
To determine:
How repressor protein does helps to regulate bacterial operon.
Concept introduction:
Operon is a functional unit of DNA that contains clusters of gene and all the genes are controlled by single promoter. Lac operon is a type of operon which is responsible for the transportation and
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Describe what would happen to the lac operon in a low-lactose environment and in a high lactose environment.
a) How will each of these environments affect gene expression?
b) What would happen to the repressor in each case?
c) How will each of these environments affect RNA polymerase?
In the absence of lactose and the lacI repressor gene is mutated such that the repressor protein product can no longer bind to the operator, the structural genes will: [ Select ] ["No longer be expressed", "Be constantly expressed", "Be deleted from the operon"]
In the presence of lactose and the lacI repressor gene is mutated such that the repressor protein product can no longer bind to the operator, the structural genes will: [ Select ] ["No longer be expressed", "Be constantly expressed", "Be deleted from the operon"]
Which of the following statements is not true of both the LacI and TrpR repressor proteins?a) an allosteric effector molecule changes the DNA-binding activity of the proteinb) transcription is blocked when the repressor protein is bound to the operatorc) the repressor protein is trans-actingd) the allosteric effector causes the repressor to release from the operatore) the operon regulated by the repressor produces the allosteric effector molecule
Chapter 7 Solutions
Biology: Concepts and Investigations
Ch. 7.1 - How did Griffiths research, coupled with the work...Ch. 7.1 - How did the Hershey-Chase blender experiments...Ch. 7.2 - What are the components of DNA and its...Ch. 7.2 - What evidence enabled Watson and Crick to decipher...Ch. 7.2 - Prob. 3MCCh. 7.3 - What is the relationship between a gene and a...Ch. 7.3 - Prob. 2MCCh. 7.3 - What are the three types of RNA, and how does each...Ch. 7.4 - What happens during each stage of transcription?Ch. 7.4 - Where in the cell does transcription occur?
Ch. 7.4 - What is the role of RNA polymerase in...Ch. 7.4 - What are the roles of the promoter and terminator...Ch. 7.4 - How is mRNA modified before it leaves the nucleus...Ch. 7.5 - How did researchers determine that the genetic...Ch. 7.5 - What happens in each stage of translation?Ch. 7.5 - Where in the cell does translation occur?Ch. 7.5 - How are polypeptides modified after translation?Ch. 7.6 - What are some reasons that cells regulate gene...Ch. 7.6 - Prob. 2MCCh. 7.6 - Prob. 3MCCh. 7.6 - Prob. 4MCCh. 7.7 - What is a mutation?Ch. 7.7 - What are the types of mutations, and how does each...Ch. 7.7 - Prob. 3MCCh. 7.7 - Prob. 4MCCh. 7.7 - How are mutations important?Ch. 7.8 - What question about the FOXP2 gene were the...Ch. 7.8 - What insights could scientists gain by...Ch. 7 - A nucleotide is composed of all of the following...Ch. 7 - Prob. 2MCQCh. 7 - Transcription copies a _______ to a complementary...Ch. 7 - Choose the DNA sequence from which this mRNA...Ch. 7 - Prob. 5MCQCh. 7 - Prob. 6MCQCh. 7 - How does the lac operon regulate lactose digestion...Ch. 7 - Prob. 8MCQCh. 7 - Prob. 9MCQCh. 7 - Prob. 10MCQCh. 7 - Explain how Griffiths experiment and Avery,...Ch. 7 - Prob. 2WIOCh. 7 - Prob. 3WIOCh. 7 - Put the following in order from smallest to...Ch. 7 - Prob. 5WIOCh. 7 - List the three major types of RNA and their...Ch. 7 - Some people compare DNA to a blueprint stored in...Ch. 7 - Prob. 8WIOCh. 7 - Prob. 9WIOCh. 7 - If a protein is 1259 amino acids long, what is the...Ch. 7 - Prob. 11WIOCh. 7 - The roundworm C. elegans has 556 cells when it...Ch. 7 - A protein-encoding region of a gene has the...Ch. 7 - Explain how a mutation in a protein-encoding gene,...Ch. 7 - Refer to the figure to answer these questions: a....Ch. 7 - Describe the mutation shown in figure 7.27 and...Ch. 7 - Prob. 17WIOCh. 7 - Parkinson disease causes rigidity, tremors, and...Ch. 7 - Refer to figure 7.28 and the chapter con tent to...Ch. 7 - Prob. 2PITCh. 7 - Prob. 3PITCh. 7 - Prob. 4PIT
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- What are the major differences between a repressor protein anda riboswitch in the control of gene expression?arrow_forwardIn the tryptophan operon of E. coli, what happens when tryptophan levels get too high? tryptophan is removed from its co-repressor, causing it to detach from the operator tryptophan is removed from its co-repressor, causing it to attach to the operator tryptophan is bound to its co-repressor, causing it to detach from the operator tryptophan is bound to its co-repressor, causing it to attach to the operator all of the above occur at equal rates when tryptophan levels get too high (Option C is the answer for the question above) What effect will the above process have on the tryptophan operon? RNA polymerase will detach from the promoter, initiating transcription RNA polymerase will detach from the promoter, stopping transcription RNA polymerase will attach to the promoter, initiating transcription RNA polymerase will attach to the promoter, stopping transcription all of the above occur at equal rates when tryptophan levels get too higharrow_forwardIn the tryptophan operon of E. coli, what happens when tryptophan levels get too high? tryptophan is removed from its co-repressor, causing it to detach from the operator tryptophan is removed from its co-repressor, causing it to attach to the operator tryptophan is bound to its co-repressor, causing it to detach from the operator tryptophan is bound to its co-repressor, causing it to attach to the operator all of the above occur at equal rates when tryptophan levels get too high (Option D is the answer for the question above) What effect will the above process have on the tryptophan operon? RNA polymerase will detach from the promoter, initiating transcription RNA polymerase will detach from the promoter, stopping transcription RNA polymerase will attach to the promoter, initiating transcription RNA polymerase will attach to the promoter, stopping transcription all of the above occur at equal rates when tryptophan levels get too higharrow_forward
- In the tryptophan operon of E. coli, what happens when tryptophan levels get too high? tryptophan is removed from its co-repressor, causing it to detach from the operator tryptophan is removed from its co-repressor, causing it to attach to the operator tryptophan is bound to its co-repressor, causing it to detach from the operator tryptophan is bound to its co-repressor, causing it to attach to the operator all of the above occur at equal rates when tryptophan levels get too high What effect will the above process have on the tryptophan operon? RNA polymerase will detach from the promoter, initiating transcription RNA polymerase will detach from the promoter, stopping transcription RNA polymerase will attach to the promoter, initiating transcription RNA polymerase will attach to the promoter, stopping transcription all of the above occur at equal rates when tryptophan levels get too higharrow_forwardIf you add a co-eepressor to a repressor protein and that allows it to bind the operator is this a inducible, constitutive or repressible operon?arrow_forward2) what is negative control of genes ? Does it need active form or inactive form of the repressor ? 3) What is role of RNA polymerase, operator and the repressor in repressible operon and inducible operons ? 4) How is eukaryotic gene expression different than bacterial gene expression ? 5) How does histone acetylation influence transcription ?arrow_forward
- What is the function of the repressor encoded by the lacI gene?arrow_forwardGene expression in bacteria is controlled by the operon model. a) Why is the operon model important? b) Why is the trp operon known as a repressible operon?arrow_forwardThe lac operon of E. coli controls the expression of genes that code for enzymes involved in lactose metabolism. Mutations to various regions of the lac operon have been discovered which affect both the control of gene expression and the function of the gene products. These mutations include: I - = produces a repressor protein that cannot bind to the operator region IS = produces a repressor protein that cannot be removed from the operator region OC = cannot bind a repressor protein Z - = produces a defective (non-functioning) β-galactosidase enzyme + = wild type Detail the functionality of the lac operon under the following genetic and cellular conditions. You do not need to consider the role of CAP in your analysis. Genes Repressed (yes/no) Constitutive (yes/no) I+ OC Z+ I+ O+ Z+ (Lactose present) I- O+ Z+arrow_forward
- The lac operon of E. coli controls the expression of genes that code for enzymes involved in lactose metabolism. Mutations to various regions of the lac operon have been discovered which affect both the control of gene expression and the function of the gene products. These mutations include: I - = produces a repressor protein that cannot bind to the operator region IS = produces a repressor protein that cannot be removed from the operator region OC = cannot bind a repressor protein Z - = produces a defective (non-functioning) β-galactosidase enzyme + = wild type Detail the functionality of the lac operon under the following genetic and cellular conditions. You do not need to consider the role of CAP in your analysis. Genes Repressed (yes/no) Constitutive (yes/no) IS O+ Z+ IS OC Z+arrow_forwardThe transcription of many bacterial genes relies on functional groups called operons, such as the tryptophan operon. What is an operon?arrow_forwardIf β-galactosidase is expressed when lactose is absent, what does this suggest about the lac operon? a) There is a mutation in the repressor protein b) There is a mutation in the catabolite activator protein c) There is a mutation in the promoter region d) There is a mutation in the luxI proteinarrow_forward
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