From the above mentioned table which patient have frameshift mutation. Concept introduction: A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

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Answer 1

Question

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

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Two missense mutations in the gene that encodes an enzyme called superoxide dismutase cause a form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig disease). This disease causes loss of neurological function over a 5-year period. One mutation alters the amino acid asparagine (Asn) to lysine (Lys). The other changes an isoleucine (Ile) to a threonine (Thr). List the codons involved and describe how single-base mutations can alter the specified amino acids.

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An example sequence corresponds to human sickle cell beta-globin mRNA and that this disease results from a point mutation in the β globin gene. In the following section, you will compare sickle cell and normal β globin sequences to reveal the nature of the sickle cell mutation at the protein level. To do this you need to find at least one sequence representing the normal beta globin gene. Open a new window and visit the NCBI home page(http://www.ncbi.nlm.nih.gov) and select “Nucleotide” from the drop menu associated with the top search box. Then enter the search term: HBB . Note that lots of irrelevant results are returned so let's apply some “Filters” (available by clicking in the left-hand sidebar) to focus on RefSeq entries for Homo sapiens. Remember that we are after mRNA so we can compare to the mRNA sequence from part 1 above. QUESTION #1: What is the ACCESSION number of the “Homo sapiens hemoglobin, beta (HBB), mRNA” entry? NOTE: Boolean operators (NOT, AND, OR) as…

Answer 2

Question

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

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Answer 3

Question

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

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Answer 4

Question

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

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Answer 5

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 6

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 7

Chapter 7, Problem 17WIO

(a)

Summary Introduction

To determine:

From the above mentioned table which patient have frameshift mutation.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 8

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 9

(b)

Summary Introduction

To determine:

From the above mentioned table how many amino acids are missing from patient E.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 10

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 11

(c)

Summary Introduction

To determine:

Which patient will produce a shortened protein.

Concept introduction:

A mutation is biological process which is defined as the permanent alteration in the nucleotide sequence of DNA. Mutation is unpredictable change that alters the protein function by changing shape of amino acid. It occurs naturally within the cell or by certain environmental factors such as ionizing and non-ionizing radiation.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 7.1 - How did Griffiths research, coupled with the work...Ch. 7.1 - How did the Hershey-Chase blender experiments...Ch. 7.2 - What are the components of DNA and its...Ch. 7.2 - What evidence enabled Watson and Crick to decipher...Ch. 7.2 - Prob. 3MC Ch. 7.3 - What is the relationship between a gene and a...Ch. 7.3 - Prob. 2MC Ch. 7.3 - What are the three types of RNA, and how does each...Ch. 7.4 - What happens during each stage of transcription?Ch. 7.4 - Where in the cell does transcription occur?

Solution Summary: The author explains that a mutation is biological process that alters the nucleotide sequence of DNA.

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