Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 7, Problem 7.4PS

QUANTITATIVE Gorter and Grendel Revisited. Gorter and Grendel’s classic conclusion that the plasma membrane of the human erythrocyte consists of a lipid bilayer was based on the following observations: (i) the lipids that they extracted with acetone from 4.74 × 109 erythrocytes formed a monolayer 0.89 m2 in area when spread out on a water surface, and (ii) the surface area of one erythrocyte was about 100 µm2, according to their measurements.

(a) Show from these data how they came to the conclusion that the erythrocyte membrane is a bilayer.

(b) We now know that the surface area of a human erythrocyte is about 145 µm2. Explain how Gorter and Grendel could have come to the right conclusion when one of their measurements was only about two-thirds of the correct value.

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The classic demonstration that cell plasma membranes are composed ofbilayers depends on the following kinds of data:• The membrane lipids from 4.74 x 109 erythrocytes will form a monolayerof area 0.89 m2 when spread on a water surface.• The surface of one erythrocyte is approximately 100 μm2 in area.Show that these data can be accounted for only if the erythrocyte membraneis a bilayer.
. The classic demonstration that cell plasma membranes are composed of bilayers depends on the following kinds of data: • The membrane lipids from 4.74 X 1o° erythrocytes will form a mono- layer of area 0.89 m² when spread on a water surface. • The surface of one erythrocyte is approximately 100 um in area. Show that these data can be accounted for only if the erythrocyte membrane is a bilayer.
- The classic demonstration that cell plasma membranes are com- posed of bilayers depends on the following kinds of data: • The membrane lipids from 4.74 x 10° erythrocytes will form a monolayer of area 0.89 m² when spread on a water surface. • The surface of one erythrocyte is approximately 100 µm? in area. Show that these data can be accounted for only if the erythrocyte membrane is a bilayer.
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The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license