Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 7, Problem 33P
Summary Introduction

To analyze:

Analyze the effect on DNA replication if mutation of DNA pol III loses each of the following activities,

  1. 5'3' polymerase activity.

  2. 3'5' exonuclease activity.

Introduction:

DNA replication is one of the basic and important processes that occurs within the cell in which a double stranded DNA molecule is copied to produce two identical DNA molecules. In prokaryotes, the replication of DNA is bidirectional, which is, processing from a single point of origin of replication to both directions, and the series of proteins and enzymes are involved in the replication mechanism.

One of the important enzymes in the DNA replication mechanism is DNA polymerase III. The main replicative enzyme is DNA polymerase III. It synthesizes a new DNA strand in 5'3' direction.

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Genetic Analysis: An Integrated Approach (3rd Edition)

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