Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 7, Problem 26P
Telomeres are found at the ends of eukaryotic chromosomes.
a. What is the sequence composition of telomeres?
b. How does telomerase assemble telomeres?
c. What is the functional role of telomeres?
d. Why is telomerase usually active in germ-line cells but not in somatic cells?
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Chapter 7 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 7 - What results from the experiments of Frederick...Ch. 7 - 7.2 Explain why Avery, MacLeod, and McCarty’s in...Ch. 7 - 7.3 Hershey and Chase selected the bacteriophage...Ch. 7 - 7.4 Explain how the Hershey and Chase experiment...Ch. 7 - 7.5 One strand of a fragment of duplex DNA has the...Ch. 7 - 7.6 The principles of complementary base pairing...Ch. 7 - For the following fragment of DNA, determine the...Ch. 7 - 7.8 Figures present simplified depictions of...Ch. 7 - 7.9 Consider the sequence -ACGCTACGTC-.
What is...Ch. 7 - DNA polymerase III is the main DNA-synthesizing...
Ch. 7 - There is a problem completing the replication of...Ch. 7 - Explain how RNA participates in DNA replication.Ch. 7 - A sample of double-stranded DNA is found to...Ch. 7 - Bacterial DNA polymerase I and DNA polymerase III...Ch. 7 - Diagram a replication fork in bacterial DNA and...Ch. 7 - Prob. 16PCh. 7 - Which of the following equalities is not true for...Ch. 7 - List the order in which the following proteins and...Ch. 7 - Two viral genomes are sequenced, and the following...Ch. 7 - Matthew Meselson and Franklin Stahl demonstrated...Ch. 7 - Raymond Rodriguez and colleagues demonstrated...Ch. 7 - 7.22 Joel Huberman and Arthur Riggs used pulse...Ch. 7 - 7.23 Why do the genomes of eukaryotes, such as...Ch. 7 - Bloom syndrome (OMIM 210900) is an autosomal...Ch. 7 - 7.25 How does rolling circle replication (see...Ch. 7 - Telomeres are found at the ends of eukaryotic...Ch. 7 - A family consisting of a mother (I-1), a father...Ch. 7 - In a dideoxy DNA sequencing experiment, four...Ch. 7 - Prob. 29PCh. 7 - Using an illustration style and labeling similar...Ch. 7 - A PCR reaction begins with one double-stranded...Ch. 7 - Prob. 32PCh. 7 - Prob. 33PCh. 7 - 7.34 A sufficient amount of a small DNA fragment...Ch. 7 - You are participating in a study group preparing...Ch. 7 - Prob. 36PCh. 7 - The following diagram shows the parental strands...Ch. 7 - Go to the OMIM website...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Cells lacking telomerase can grow for several cell divisions without obvious defects. However, after more cell divisions, such cells tend to show chromosomes that have fused together. Propose an explanation for the formation of the chromosomes.arrow_forwardUsing a diagram, and 3-5 sentences, explain the relationship between cell immortality and telomerase activity. Please help me with this! Thank you!arrow_forwardOf the following statements related to the function of telomeres, identify which is FALSE. a. Telomeres protect organisms from cancer by limiting the number of somatic cell divisions b. Telomeres help prevent unnecessary cell death by preventing DNA monitoring activity at the staggered ends of DNA c. Telomeres restore the length of lagging DNA strands in germ cells d. Telomeres offer some protection against the unavoidable shortening of genesarrow_forward
- Which types of chromosome mutations a. increase the amount of genetic material in a particular chromosome? b. increase the amount of genetic material in all chromosomes? c. decrease the amount of genetic material in a particular chromosome? d. change the position of DNA sequences in a single chromosome without changing the amount of genetic material? e. move DNA from one chromosome to a nonhomologous chromosome?arrow_forward4. Which statement about telomeres is incorrect? A) Telomeres are repetitive nucleotide sequences at- the end of a chromatid B) Telomeres serve as protective caps that prevent chromosome from deterioration during cell division C) Telomeres are gradually consumed during repeated the cell divisions D) In cancer cells, telomerase activity is usually re- duced compared with normal cellsarrow_forwardWhich of the following statements are correct about telomeres (select all that apply)? A. A total of 6 nucleotides are lost at the end of each chromsome during each replication cycle. B. Addition of telomerase to cells that have undergone breakage-fusion-bridge cycles can reverse crisis C. Shortening of telomeres prevents cells from becoming cancerous even if they have oncogenes and defective tumor suppressor genes D. All cancer cells express high levels of telomerase E. Chromosomes without telomeres tend to undergo end-to-end fusionsarrow_forward
- Certain organisms contain cells that possess polytene chromosomes. What are polytene chromosomes, where are they found, and what function do they serve?arrow_forwardWhat difference exists between the compaction of chromosomes during metaphase versus interphase? Give at least one reason why this difference may be necessary.arrow_forwardBob's telomerase works extremely well (10x better than the average humans). Explain the function of telomerase in normal people. Describe one advantage to Bob that you would predict. Describe one disadvantage for Bob you might predict. (3 sentences)arrow_forward
- A. In NOT more than 200 words, explain how the double-helical structure of DNA suggests a mechanism for DNA replication? B. In NOT more than 200 words, explain the special mechanism used to replicate chromosome ends?arrow_forwardThink about the important functions of telomeres. Now, imagine a scenario in which a mutant eukaryotic cell DID NOT have such specialized telomeric regions present on its chromosomes. List three major CONSEQUENCES of the lack of telomeres, based upon what you know about their normal functions.arrow_forwardUsing the figure below identify: What is the role of histones and nucleosomes? How the process of chromatin condensation is performed? What is a function of introns and exons? What is a role of mobile DNA elements? What is a meaning of simple-sequence DNA?arrow_forward
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