Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 7, Problem 27P
Imagine that you caught a female albino mouse in your kitchen and decided to keep it for a pet. A few months later, while vacationing in Guam, you caught a male albino mouse and decided to take it home for some interesting genetic experiments. You wonder whether the two mice are both albino due to mutations in the same gene. What could you do to find out the answer to this question? Assume that both mutations are recessive.
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Students have asked these similar questions
Starting with a population of genetically identical mice, you discover two new independent mutant
strains in which all of the animals have epileptic seizures. In both strains, you know that the epileptic
seizures are due to a single recessive mutation. You cross a mutant mouse from one strain to a
mutant mouse from the second strain and find that none of their many offspring undergo
spontaneous seizures. From this experiment you would conclude that the two mutant strains of mice
most likely have mutations in:
two different genes
the same gene, but not necessarily the same DNA base position
the same DNA base position within a particular gene
Imagine that you caught a female albino mouse inyour kitchen and decided to keep it for a pet. A fewmonths later, while vacationing in Guam, you caughta male albino mouse and decided to take it home forsome interesting genetic experiments. You wonderwhether the two mice are both albino due to mutations in the same gene. What could you do to find outthe answer to this question? Assume that both mutations are recessive.
An undergraduate researcher in your lab is studying mutations affecting the wings of Drosophila melanogaster. She has identified two mutant phenotypes of interest:
bent wings (be), which are recessive to the wild-type straight wings (be+), and
apterous (ap) mutants (which are wingless). The apallele is recessive to the wild-type allele (ap+), which allows wings to develop.
If a homozygous bent-winged fly (which possesses the normal allele of apterous) is crossed with a homozygous wingless fly (which possesses the normal allele of bent wings), what phenotypic ratio would you expect to observe in the F2 generation of this cross?
a) Please indicate the ratio, including the genotypes and phenotypes of all phenotypic classes.
Phenotype: Genotype(s) corresponding to this phenotype
Phenotypic ratio: (Be sure to NAME the classes in the ratio).
B) Please NAME and DEFINE the type of gene interaction illustrated in this example.
Chapter 7 Solutions
Genetics: From Genes to Genomes
Ch. 7 - The following is a list of mutational changes. For...Ch. 7 - What explanations can account for the following...Ch. 7 - The DNA sequence of one strand of a gene from...Ch. 7 - Among mammals, measurements of the rate of...Ch. 7 - Over a period of several years, a large hospital...Ch. 7 - Suppose you wanted to study genes controlling the...Ch. 7 - In a genetics lab, Kim and Maria infected a sample...Ch. 7 - The results of the fluctuation test Fig. 7.5 were...Ch. 7 - The following pedigree shows the inheritance of a...Ch. 7 - Autism is a neurological disorder thought to be...
Ch. 7 - Like the yellow Labrador retrievers featured in...Ch. 7 - Remember that Balancer chromosomes prevent the...Ch. 7 - Figure 7.14 shows examples of base substitutions...Ch. 7 - Figure 7.14a shows the mutagen 5-bromouracil 5-BU,...Ch. 7 - So-called two-way mutagens can induce both a...Ch. 7 - In 1967, J. B. Jenkins treated wild-type male...Ch. 7 - When a particular mutagen identified by the Ames...Ch. 7 - Prob. 18PCh. 7 - The Ames test uses the reversion rate His- to His...Ch. 7 - The mutant FMR-1 allele that causes fragile X...Ch. 7 - The physicist Stephen Hawking, famous for his...Ch. 7 - Aflatoxin B1 is a highly mutagenic and...Ch. 7 - In human DNA, 70 of cytosine residues that are...Ch. 7 - Bromodeoxyuridine BrdU is a synthetic nucleoside...Ch. 7 - Albinism in animals is caused by recessive...Ch. 7 - a. In Figure 7.22b, what can you say about the...Ch. 7 - Imagine that you caught a female albino mouse in...Ch. 7 - Plant breeders studying genes influencing leaf...Ch. 7 - In humans, albinism is normally inherited in an...Ch. 7 - a. Seymour Benzers fine structure analysis of the...Ch. 7 - a. You have a test tube containing 5 ml of a...Ch. 7 - Prob. 32PCh. 7 - The rosy ry gene of Drosophila encodes an enzyme...Ch. 7 - Nine rII- mutants of bacteriophage T4 were used in...Ch. 7 - In a haploid yeast strain, eight recessive...Ch. 7 - In Problem 24, you learned that Bloom syndrome is...Ch. 7 - The pathway for arginine biosynthesis in...Ch. 7 - In corn snakes, the wild-type color is brown. One...Ch. 7 - In a certain species of flowering plants with a...Ch. 7 - The intermediates A, B, C, D, E, and F all occur...Ch. 7 - In each of the following cross schemes, two...Ch. 7 - Prob. 42PCh. 7 - The following complementing E. coli mutants were...Ch. 7 - In 1952, an article in the British Medical Journal...Ch. 7 - Mutations in an autosomal gene in humans cause a...Ch. 7 - Antibodies were made that recognize six proteins...Ch. 7 - Prob. 47PCh. 7 - Prob. 48PCh. 7 - In addition to the predominant adult hemoglobin,...Ch. 7 - Most mammals, including New World primates such as...Ch. 7 - Humans are normally trichromats; we have three...
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY