Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 7, Problem 38P
In corn snakes, the wild-type color is brown. One autosomal recessive mutation causes the snake to be orange, and another causes the snake to be black. An orange snake was crossed to a black one, and the F offspring were all brown. Assume that all relevant genes are unlinked.
| a.. | Indicate what pigment pathway, with orange and black being different intermediates on the way to brown. |
| b.. | Indicate what phenotypes and ratios you would expect in the F2 generation if orange pigment is a product of one pathway, black pigment is the product of another pathway, and brown is the effect of mixing the two pigments in the skin of the snake. |
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In corn snakes, the wild-type color is brown. Oneautosomal recessive mutation causes the snake to beorange, and another causes the snake to be black. Anorange snake was crossed to a black one, and the F1offspring were all brown. Assume that all relevantgenes are unlinked.a. Indicate what phenotypes and ratios you wouldexpect in the F2 generation of this cross if there isone pigment pathway, with orange and black beingdifferent intermediates on the way to brown.b. Indicate what phenotypes and ratios you wouldexpect in the F2 generation if orange pigment is aproduct of one pathway, black pigment is the product of another pathway, and brown is the effect ofmixing the two pigments in the skin of the snake
In an autotetraploid Chinese primrose (Primula sinensis), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain.
a. What is the genotype of the F1?
b. Show the types of gametes the F1’s may be expected to form and derive the expected proportion of each.
c. What phenotypic ratio of green to red is expected if:
1. The F1’s are intercrossed?
2. The F1’s are crossed with red plants
d. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the F1 be expected to produce? Derive the expected F2 phenotypic ratio.
In autotetraploid Chinese primrose (Primula sinensis L.), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain.
a. What is the genotype of the Fl1?
b. Show the types of gametes the Fl's may be expected to form and derive the expected proportion of each. Show your solution.
c. What phenotypic ratio of green to red is expected if:
the Fl's are intercrossed? Show your solution.
the Fl's are crossed with red plants? Show your solution.
d. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the Fl be expected to produce? Derive the expected F2 phenotypic ratio.
Chapter 7 Solutions
Genetics: From Genes to Genomes
Ch. 7 - The following is a list of mutational changes. For...Ch. 7 - What explanations can account for the following...Ch. 7 - The DNA sequence of one strand of a gene from...Ch. 7 - Among mammals, measurements of the rate of...Ch. 7 - Over a period of several years, a large hospital...Ch. 7 - Suppose you wanted to study genes controlling the...Ch. 7 - In a genetics lab, Kim and Maria infected a sample...Ch. 7 - The results of the fluctuation test Fig. 7.5 were...Ch. 7 - The following pedigree shows the inheritance of a...Ch. 7 - Autism is a neurological disorder thought to be...
Ch. 7 - Like the yellow Labrador retrievers featured in...Ch. 7 - Remember that Balancer chromosomes prevent the...Ch. 7 - Figure 7.14 shows examples of base substitutions...Ch. 7 - Figure 7.14a shows the mutagen 5-bromouracil 5-BU,...Ch. 7 - So-called two-way mutagens can induce both a...Ch. 7 - In 1967, J. B. Jenkins treated wild-type male...Ch. 7 - When a particular mutagen identified by the Ames...Ch. 7 - Prob. 18PCh. 7 - The Ames test uses the reversion rate His- to His...Ch. 7 - The mutant FMR-1 allele that causes fragile X...Ch. 7 - The physicist Stephen Hawking, famous for his...Ch. 7 - Aflatoxin B1 is a highly mutagenic and...Ch. 7 - In human DNA, 70 of cytosine residues that are...Ch. 7 - Bromodeoxyuridine BrdU is a synthetic nucleoside...Ch. 7 - Albinism in animals is caused by recessive...Ch. 7 - a. In Figure 7.22b, what can you say about the...Ch. 7 - Imagine that you caught a female albino mouse in...Ch. 7 - Plant breeders studying genes influencing leaf...Ch. 7 - In humans, albinism is normally inherited in an...Ch. 7 - a. Seymour Benzers fine structure analysis of the...Ch. 7 - a. You have a test tube containing 5 ml of a...Ch. 7 - Prob. 32PCh. 7 - The rosy ry gene of Drosophila encodes an enzyme...Ch. 7 - Nine rII- mutants of bacteriophage T4 were used in...Ch. 7 - In a haploid yeast strain, eight recessive...Ch. 7 - In Problem 24, you learned that Bloom syndrome is...Ch. 7 - The pathway for arginine biosynthesis in...Ch. 7 - In corn snakes, the wild-type color is brown. One...Ch. 7 - In a certain species of flowering plants with a...Ch. 7 - The intermediates A, B, C, D, E, and F all occur...Ch. 7 - In each of the following cross schemes, two...Ch. 7 - Prob. 42PCh. 7 - The following complementing E. coli mutants were...Ch. 7 - In 1952, an article in the British Medical Journal...Ch. 7 - Mutations in an autosomal gene in humans cause a...Ch. 7 - Antibodies were made that recognize six proteins...Ch. 7 - Prob. 47PCh. 7 - Prob. 48PCh. 7 - In addition to the predominant adult hemoglobin,...Ch. 7 - Most mammals, including New World primates such as...Ch. 7 - Humans are normally trichromats; we have three...
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