Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Textbook Question
Chapter 6.6, Problem 9LO
Cite evidence supporting a long evolutionary history for cell signaling molecules.
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Cell Communications
Explain the role of the trans-membrane and the intracellular protein receptors in cell signaling (provide an example of each).
Why do we need to identify and determine the function of every single molecule involved in cell signalling? provide citations of trusted papers/sites. (no less than 250 words)
compare and contrast how GPCRs and RTKs transduce their signal to the cell? include the types of ligands they bind, the GTP binding protein that is activated, and how the signal is transduced and amplified. what effects does it have on the cell?
Chapter 6 Solutions
Biology (MindTap Course List)
Ch. 6.1 - Describe the four main processes essential for...Ch. 6.1 - What is the sequence of events that takes place in...Ch. 6.1 - Prob. 2CCh. 6.2 - Compare three types of signaling molecules:...Ch. 6.2 - Prob. 1CCh. 6.2 - Prob. 2CCh. 6.2 - Prob. 3CCh. 6.3 - Identify mechanisms that make reception a highly...Ch. 6.3 - Prob. 4LOCh. 6.3 - Prob. 1C
Ch. 6.3 - Prob. 2CCh. 6.3 - Prob. 3CCh. 6.3 - Prob. 4CCh. 6.4 - Prob. 5LOCh. 6.4 - Trace the sequence of events in signal...Ch. 6.4 - How is an extracellular signal converted to an...Ch. 6.4 - Prob. 2CCh. 6.4 - Prob. 3CCh. 6.5 - Prob. 7LOCh. 6.5 - Prob. 8LOCh. 6.5 - Prob. 1CCh. 6.5 - Prob. 2CCh. 6.5 - Prob. 3CCh. 6.6 - Cite evidence supporting a long evolutionary...Ch. 6.6 - Prob. 1CCh. 6 - During signal transduction (a) the cell converts...Ch. 6 - When a signaling molecule binds with a receptor,...Ch. 6 - G proteinlinked receptors (a) inactivate G...Ch. 6 - Prob. 4TYUCh. 6 - Prob. 5TYUCh. 6 - Calcium ions (a) can act as second messengers (b)...Ch. 6 - When growth hormone binds to an enzyme-linked...Ch. 6 - Scaffold proteins (a) release kinases and...Ch. 6 - Prob. 9TYUCh. 6 - Prob. 10TYUCh. 6 - More than 500 genes have been identified in the...Ch. 6 - Prob. 12TYUCh. 6 - Prob. 13TYUCh. 6 - EVOLUTION LINK Cell signaling in plant and animal...Ch. 6 - EVOLUTION LINK Some of the same G proteinlinked...Ch. 6 - Prob. 16TYU
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- For cellular transduction, why is it useful that phosphorylation cascades have a series of protein kinases? a. they amplify the original signal b. they always lead to the same cellular response c. the number of molecules used is small and fixed d. they are cell specificarrow_forwardProvide an overview of the cell signaling process.arrow_forwardUsing examples, describe the signalling pathway from receptor tyrosinekinase activation to gene transcription, highlighting key phosphorylationevents and domains involvedarrow_forward
- Can you please describe the role of G proteins in ligand-activated cellular signal transduction.arrow_forwardWhy is the GTPase activity of G proteins crucial to the proper functioning of a cell? Propose a theory as to why G proteins have not evolved to catalyze GTP hydrolysis more efficiently.arrow_forwardMPF plays an important role during the regulation of the cell cycle. give examples that will support this statement.arrow_forward
- What is the benefit of using second messangers and phosphorylation cascades during the transduction step of cell signaling?arrow_forwardThe output of RTK pathways is often the activation of MAP Kinase. Explain how MAPK can lead to activation of a specific subset of proteins, leading to distinct effects in different cell types in response to the same growth signal.arrow_forwardCell signaling in plant and animal cells is similar in those ways and different in others. Offer one or more hypotheses for these similarities and differences, and cite specific examples.arrow_forward
- Which of these pathways is highly conserved among invertebrates and mammals regarding stem cell niche signaling? a. Wnt and beta-catenin families b. MAP kinase family c. VegT and Veg 1 family d. Pitx familyarrow_forwardPlease explain two distances of signalingarrow_forwardFor each of the following situations, provide a plausible explanation for how it could lead to unrestricted cell division.(a) Colon cancer cells often contain mutations in the gene encoding the prostaglandin E2 receptor. PGE2 is a growth factor required for the division of cells in the gastrointestinal tract.(b) Kaposi sarcoma, a common tumor in people with untreated AIDS, is caused by a virus carrying a gene for a protein similar to the chemokine receptors CXCR1 and CXCR2. Chemokines are cell-specific growth factors.(c) Adenovirus, a tumor virus, carries a gene for the protein E1A, which binds to the retinoblastoma protein, pRb. (d) An important feature of many oncogenes and tumor suppressor genes is their celltype specificity. For example, mutations in the PGE2 receptor are not typically found in lung tumors. Explain this observation. (Note that PGE2 acts through a GPCR in the plasma membrane.)arrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license