Human Physiology: An Integrated Approach (8th Edition)
Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 6.2, Problem 7CC
Summary Introduction

To determine: The events that take place during the process of amplification.

Introduction: The communication between the cells is essential to transport information to the cells. Cell-to-cell communication is done with the help of signal transduction pathways. Signal transduction pathway initiates a series of events, which generates the extracellular response.

Summary Introduction

To determine: The number of signaling molecules that are amplified in the figure is given in the book.

Introduction: Signal transduction pathway is a series of events that transfer the particular information to the cells. This pathway begins when a ligand attaches with a receptor present on the cells. The signals carried by a ligand are not sufficient to generate the response. Hence, these signals are amplified to produce a response.

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In most neurons, membrane depolarization leads to the opening of voltage-dependent ion channels, generation of an action potential, and, ultimately, an influx of Ca2+, which causes release of neurotransmitter at the axon terminus. Devise a cellular strategy by which hyperpolarization in rod cells could produce excitation of the visual pathway and passage of visual signals to the brain. (Hint: The neuronal signaling pathway in higher organisms consists of a series of neurons that relay information to the brain. The signal released by one neuron can be either excitatory or inhibitory to the following, postsynaptic neuron.)
Sensory neurons in the homeostatic pathway demonstrate spontaneous activity.  For a neuron, what does spontaneous activity mean? Describe a mechanism by which a neuron would demonstrate spontaneous activity. (Good inspiration would be to look at the mechanism of behavior and effect on membrane potentials of HCN channels in the heart.) Assuming these sensory neurons used FM communication, how do they encode increases in stimulation and also to encode decreases in stimulation of receptors?
Why do different cells respond to the same stimulus in different ways? State three potential outcomes of signal transduction events.

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Human Physiology: An Integrated Approach (8th Edition)

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