Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 6, Problem 12RQ
Explain the relationships of the terms in each of the following sets. Give a physiological example or location if applicable.
- a. gap junctions, connexins, connexon
- b. autocrine signal, paracrine signal
- c. cytokine, neurotransmitter, neurohormone, neuromodulator, hormone
- d. Receptor agonist, receptor antagonist, antagonistic control pathways
- e. transduction, amplification, cascade
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Which of the following statements is truc
a. Neurotransmitters must bind to a receptor to exert an action on a cell but hormones do not have
to bind to a receptor to exert an action
b. The nervous system effects are longer lasting than the endocrine system
c. The nervous system effects are faster to respond than the endocrine system
d. The nervous system releases neurotransmitters into the bloodstream similar to how the
endocrine system releases hormones into the bloodstream
compare small molecule neurotransmitters to neuropeptides
Select one:
a. neuropeptides are synthesized as large peptide molecules that are cleaved to form smaller peptides; neurotransmitters are modified amino acids
b. neuropeptides bind to metabotropic receptors; neurotransmitters bind to ionotropic or metabotropic receptors
c. neuropeptides are slower to replenish in the axon terminal than neurotransmitters
d. all of these are valid comparisons
e. neuropeptides are released by cells that express the peptide gene; neurotransmitters are released by cells that express the synthetic enzymes required to convert amino acid precursors
Define the following terms: a. downregulation b. tropic hormone c. G protein-coupled receptor d. G protein e. cAMP
Chapter 6 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 6.1 - Match the communication method on the left with...Ch. 6.1 - Which signal molecules listed in the previous...Ch. 6.1 - A cat sees a mouse and pounces on it. Do you think...Ch. 6.2 - List four components of signal pathways.Ch. 6.2 - Prob. 5CCCh. 6.2 - What are the four steps of signal transduction?Ch. 6.2 - Prob. 7CCCh. 6.2 - Prob. 8CCCh. 6.2 - Name the four categories of membrane receptors.Ch. 6.2 - Prob. 10CC
Ch. 6.2 - Prob. 11CCCh. 6.2 - Prob. 12CCCh. 6.3 - The extracellular fluid Ca2+ concentration...Ch. 6.3 - Prob. 14CCCh. 6.4 - What do receptors, enzymes, and transporters have...Ch. 6.4 - Prob. 16CCCh. 6.4 - Prob. 17CCCh. 6.5 - What is the difference between tonic control and...Ch. 6.5 - Prob. 19CCCh. 6.5 - What is the difference between local control and...Ch. 6.5 - Name the seven steps in a reflex control pathway...Ch. 6.5 - Prob. 22CCCh. 6.5 - Prob. 23CCCh. 6.5 - Prob. 24CCCh. 6 - What are the two routes for long-distance signal...Ch. 6 - Prob. 2RQCh. 6 - Prob. 3RQCh. 6 - Prob. 4RQCh. 6 - Prob. 5RQCh. 6 - An enzyme known as protein kinase adds the...Ch. 6 - Distinguish between central and peripheral...Ch. 6 - Prob. 8RQCh. 6 - Prob. 9RQCh. 6 - Prob. 10RQCh. 6 - Prob. 11RQCh. 6 - Explain the relationships of the terms in each of...Ch. 6 - List and compare the four classes of membrane...Ch. 6 - Prob. 14RQCh. 6 - Prob. 15RQCh. 6 - Prob. 16RQCh. 6 - Prob. 17RQCh. 6 - Identify the target tissue or organ for each...Ch. 6 - Now identify the integrating center for examples...Ch. 6 - In each of the following situations, identify the...Ch. 6 - Prob. 21RQCh. 6 - Prob. 22RQ
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- example of endogenous substances that mediate or transmit noceiptive signaling include. A. substance P, CGRP, bradykinin B.substance P, CGRP,enkaphin C. morphine, substance P, bradykhin D.endorphins, substance P, CGRParrow_forwardWhat features are remarkable about steroid receptors? (Select all that apply) A. Steroid receptors are localized in the cytoplasm B. steroid receptors are localized in the plasma membrane C. steroid receptors can translocate to the nucleus D. steroid receptors represent the beginning of a signaling Cascade E. steroid receptors can also function as transcription factorsarrow_forwardSelect All statements that are TRUE regarding the effects of administering a molecule that is a precursor for the synthesis of a neurotransmitter A. Temporarily compensate for neuron cell death by increased release of the neurotransmitter (ex. L-dopa used as treatment for Parkinson’s disease) B. Increase the rate of synthesis of that neurotransmitter C. Block the reuptake of the neurotransmitter back into the axon terminal D. Immediately alter then number of postsynaptic receptors E. Act as an indirect antagonist by activating autoreceptorsarrow_forward
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- E: Using either GPCRs (G-protein couples receptors) or RTKs (Receptor tyrosine kinases), describe: 1. How ligand binding activates the receptor. Ex: which proteins are involved? what changes can occur to the receptor after binding the ligand? 2. A signal transduction pathway that occurs due to the ligand binding (must include a secondary messenger). 3. Any cellular response due to the ligand binding. 4. A way that the signal pathway is regulated.arrow_forwardWhich of the following is true of neuropeptides?A. They produce effects that last for minutes.B. They are chemically similar to the genes on a chromosome.C. They are released close to their receptors.D. They are released from the tip of an axon.arrow_forwardLocal anesthetics "block" the action potential and therefore do not allow "pain" information to proceed to the brain and spinal cord. In the presence of these molecules (local anesthetics) 'threshold' is essentially "ignored". The molecules most logically work by: 23. a. Decreasing the intracellular [potassium] b. Blocking the opening of the voltage-gated potassium channels c. Decreasing the extracellular [sodium] d. Blocking the opening of the voltage-gated sodium channelsarrow_forward
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