Concept explainers
(a)
To explain: The biological relevance related to the release of hormones epinephrine and glucagon into the blood stream.
Introduction: The enzymes and the hormones can work together in the body system to regulate the activity of the enzyme. The hormones bind to the receptors on the cell membrane and can trigger enzyme activation or deactivation.
(b)
To explain: The biological relevance of allosteric inhibition of glycogen phosphorylase by a high concentration of glucose or ATP within the liver cell.
Introduction: Allosteric inhibition is caused by the allosteric inhibitors that bind to the allosteric site of the enzyme and causes a change in the active site in order to prevent binding of the substrate.
(c)
To explain: The biological relevance of activation of procarboxypeptidase by proteolytic cleavage in the duodenum of the small intestine.
Introduction: The human pancreas synthesizes and secretes the proteolytic enzyme carboxypeptidase. This enzyme is in an inactive form called procarboxypeptidase. It is activated by enzyme trypsin which cleaves this enzyme in the duodenum of the small intestine.
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Becker's World of the Cell (9th Edition)
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