Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Question
Chapter 41.5, Problem 3CC
Summary Introduction
To explain: The effect of insulinomas on blood glucose levels and liver functions.
Introduction:
Insulinomas are cancerous insulin-producing beta cells of pancreatic islets of Langerhans. These tumors lack response to feedback mechanisms and secret insulin even when there is a low blood glucose level in the body.
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Match the molecule involved in insulin signaling with what it does
insulin receptor
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physically pushes glucose out of the cell
physically brings glucose into the cell
binds to insulin and sends signal to cell
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近
5. There is an expression: diabetes mellitus is «hunger among abundance. What
metabolic changes in diabetes confirm the validity of this statement? For
answer:
9.8. Metabolic Changes in Diabetes Mellitus
535
a) list the main causes of metabolic changes in IDDM;
b) enumerate the tissues with the main energy sources metabolism procceding
according to this type of starvation;
c) name the metabolic pathways that are activated and inhibited in these tissues,
and explain why;
d) list the symptoms of diabetes mellitus, that reflect such metabolic changes;
c) draw a diagram of one of the mctabolic pathways that is activated in the liver
under these conditions and explain the consequences of such activation.
. What would be the effect of a mutation in the gene for PTP1B (protein tyrosine phosphatase 1B) that inactivated the enzyme in a person who has type 2 diabetes?
Chapter 41 Solutions
Campbell Biology
Ch. 41.1 - An animal requires 20 amino acids to make...Ch. 41.1 - Prob. 2CCCh. 41.1 - WHAT IF? If a zoo animal eating ample food shows...Ch. 41.2 - Prob. 1CCCh. 41.2 - In what sense are nutrients from a recently...Ch. 41.2 - Prob. 3CCCh. 41.3 - Explain why a proton pump inhibitor, such as the...Ch. 41.3 - Prob. 2CCCh. 41.3 - Prob. 3CCCh. 41.4 - Prob. 1CC
Ch. 41.4 - What features of a mammal's digestive system make...Ch. 41.4 - WHAT IF? "Lactose-intolerant" people have a...Ch. 41.5 - Explain how people can become obese even if their...Ch. 41.5 - WHAT IF? Suppose you were studying two groups of...Ch. 41.5 - Prob. 3CCCh. 41 - Prob. 41.1CRCh. 41 - Propose an artificial diet that would eliminate...Ch. 41 - Prob. 41.3CRCh. 41 - How does human anatomy indicate that our primate...Ch. 41 - Prob. 41.5CRCh. 41 - Fat digestion yields fatty acids and glycerol....Ch. 41 - The mammalian trachea and esophagus both connect...Ch. 41 - Prob. 3TYUCh. 41 - Prob. 4TYUCh. 41 - Prob. 5TYUCh. 41 - After surgical removal of the gallbladder, a...Ch. 41 - If you were to jog 1 km a few hours after lunch,...Ch. 41 - DRAW IT Create a flowchart to summarize the events...Ch. 41 - EVOLUTION CONNECTION Lizards and snakes cannot...Ch. 41 - SCIENTIFIC INQUIRY In human populations of...Ch. 41 - WRITE ABOUT A THEME: ORGANIZATION Hair is largely...Ch. 41 - SYNTHESIZE YOUR KNOWLEDGE Hummingbirds are well...
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- WHAT IF? Suppose you were studying two groupsof obese people with genetic abnormalities in theleptin pathway. In one group, the leptin levels areabnormally high; in the other group, they are abnormally low. How would each group’s leptin levels changeif they ate a low-calorie diet for an extended period?Explain.arrow_forwardWhich of the following are true about how pancreatic β cells sense blood glucose levels and release insulin? (select all that apply) Group of answer choices The first step of glycolysis (producing glucose 6-phosphate) is more efficient in pancreatic β cells than in muscle glucose transporters in pancreatic β cells have a higher affinity for glucose than the transporters in other tissues Increased production of ATP is used as a signal that blood glucose is high Insulin is released when blood glucose levels are high Increases in ATP open a K+ channel Influx of Ca2+ stimulates insulin releasearrow_forwardDrink # Glucose Concentration in mM 1 2.455 mM 2 0.307 mM 3 3.750 mM 4 1.100 mM 5 1.500 mM From here, each group needs to convert the concentration of their drink from mM of the diluted drink into g/100mL of the undiluted drink. This is where you come in! The students are stuck at this point and really need your help! Main Goal: Convert the experimental glucose concentration (provided in the table below) from mM (millimolar) to g/100 mL. Hints & Tips Take the 1/100 dilution factor into consideration Molarity will open the doors for you to get to grams. Once at M assume 1L of solution. (Hint: this will help you when converting from M to moles) You will also need to calculate the molar mass of glucose which has the formula C6H12O6 There are 5 steps in total Task 1: Write a step-by-step guide with key words for the Chem 2 students on how to do these calculations. You can use diagrams, a table or just type the steps out. Ensure the steps…arrow_forward
- Drink # Glucose Concentration in mM 1 2.455 mM 2 0.307 mM 3 3.750 mM 4 1.100 mM 5 1.500 mM From here, each group needs to convert the concentration of their drink from mM of the diluted drink into g/100mL of the undiluted drink. This is where you come in! The students are stuck at this point and really need your help! Main Goal: Convert the experimental glucose concentration (provided in the table below) from mM (millimolar) to g/100 mL. Hints & Tips Take the 1/100 dilution factor into consideration Molarity will open the doors for you to get to grams. Once at M assume 1L of solution. (Hint: this will help you when converting from M to moles) You will also need to calculate the molar mass of glucose which has the formula C6H12O6 There are 5 steps in total Task 1: Write a step-by-step guide with key words for the Chem 2 students on how to do these calculations. You can use diagrams, a table or just type the steps out. Ensure the steps…arrow_forwardl zain IQ ? 2:39 PM @ 73% < Вack Essential Biochemistry transduction would such changes have? For the answer: draw the scheme of insulin signal transduction in the target cell; name proteins and enzymes, activated by insulin in the target eells; c) explain the functions of these enzymes. 3. Steroid hormone calcitriol activates an intake of dictary calcium, increasing the amount of Ca" transport proteins in the gut cells. Explain the calcitriol mechanisms of action. For that: a) draw a general scheme of a signal transduction by steroid hormones and explain the process; b) name the molccules, which synthesis is activated by a hormone in the nucleus of a target cell; c) explain the function of these molccules in the cytoplasm of the target cel. 4. Copy Table 4.1 to your notebooks and fill itin. 214 Chapter 4. Structure and functions of biological membranes. Cell signaling pathways Table 4.1. Adenylyl cyclase and phosphatidylinositol 45-bisphosphate (PIP) signaling pathways Adenylyl…arrow_forwardGiven insulin's structure, where is its target likely located? Insulin's adverse side effects include headache, nau- sea, hunger, confusion and weakness. What can these symptoms be attributed to? Insulin has major effects on muscle and adipose tissue. It increases the rate of glucose transport across the cell membrane, decreases the rate of lipolysis, and increases uptake of triglycerides and some amino acids from the blood. In doing so, what metabolic processes does it favor? Carbohydrates: Lipids: Proteins:arrow_forward
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