Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 31, Problem 15P
Interpretation Introduction

Interpretation:

The reason should be determined for the recognition of the different faces of a tRNA molecule by two classes of aminoacyl-tRNA synthetase enzyme.

Concept introduction:

Protein synthesis (translation) is a process of generating new protein sequences inside the cell. This process takes place in the cytoplasm of the cell. This process is balanced by the degradation or export of cellular proteins. It is constituted of three steps namely, initiation, elongation, and termination. During this process, the function of aminoacyl-tRNA synthetase is to form an ester bond between an amino acid and its respective tRNA.

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True or False. Explain. A) At no time during protein synthesis does an amino acid make direct contact with the mRNA being translated. B) Because the two strands of DNA are complementary, the mRNA of a gene can be synthesized using either strand as a template.
tRNA enzyme. Any given aminoacyl-tRNA synthetase: a. Attaches the amino acid to the 5′-end '5end of the tRNA b. Always recognizes only one specific tRNA c. Recognizes all tRNA molecules d. Forms an ester linkage between the amino acid and the tRNA
Using threonyl-tRNA synthetase as an example, account for the specificity of threonyl-tRNA formation.
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