Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 3, Problem 9EQ
A rare form of dwarfism that also included hearing loss was found to run in a particular family. It is inherited as a dominant trait. It was discovered that an affected individual had one normal copy of chromosome 15 and one abnormal copy of chromosome 15 that was unusually long. How would you determine if the unusually long chromosome 15 was causing this disorder?
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A rare form of dwarfism that also includes hearing loss was found to run in a particular family. It is inherited in a dominant manner. It was discovered that an affected individual had one normal copy of chromosome 15 and one abnormal copy of chromosome 15 that was unusually long. How would you determine if the unusually long chromosome 15 was causing this disorder?
Infants born with Patau syndrome have an extra copy of chromosome 13, which leads to developmental abnormalities such as cleft lip and palate, small eyes, and extra fingers and toes. Another type of genetic disorder, Turner syndrome, results from the presence of only one sex chromosome—an X chromosome. Individuals born with one X chromosome are females exhibiting few noticeable defects until puberty, when they fail to develop normal breasts and internal sexual organs. what is more information about these genetic diseases on how they relate and differ?
A girl and a boy were born to a young married couple. The girl is absolutely healthy.
The examination of the boy's karyotype has shown 46 chromosomes. But one of the
chromosomes of the 15th pair is longer than normal as a part of a chromosome from
the 21st pair has joined it. How many autosomes and sex chromosomes are in the
boy's karyotype? Name the type of the mutation. Is it possible to consider this
pathology an inherited disorder?
Chapter 3 Solutions
Genetics: Analysis and Principles
Ch. 3.1 - 1. Which of the following is not found in a...Ch. 3.1 - When preparing a karyotype, which of the following...Ch. 3.1 - How many sets of chromosomes are found in a human...Ch. 3.2 - Binary fission a. is a form of asexual...Ch. 3.2 - Prob. 2COMQCh. 3.2 - What critical event occurs during the S phase of...Ch. 3.3 - 1. What is the function of the kinetochore during...Ch. 3.3 - Prob. 2COMQCh. 3.4 - Prob. 1COMQCh. 3.4 - Which phase of meiosis is depicted in the drawing...
Ch. 3.5 - In animals, a key difference between...Ch. 3.5 - Which of the following statements regarding plants...Ch. 3.6 - Which of the following is not one of the tenets of...Ch. 3.6 - A pea plant has the genotype TtRr. The independent...Ch. 3.6 - In mammals, sex is determined by a. the SRY gene...Ch. 3.6 - An abnormal fruit fly has two sets of autosomes...Ch. 3 - The process of binary fission begins with a single...Ch. 3 - 2. What is a homolog? With regard to genes and...Ch. 3 - What is a sister chromatid? Are sister chromatids...Ch. 3 - With regard to sister chromatids, which phase of...Ch. 3 - A species is diploid and has three chromosomes per...Ch. 3 - How does the attachment of kinetochore...Ch. 3 - 7. For the following events, specify whether they...Ch. 3 - Prob. 8CONQCh. 3 - A cell is diploid and contains three chromosomes...Ch. 3 - Prob. 10CONQCh. 3 - A eukaryotic cell is diploid and contains 10...Ch. 3 - Prob. 12CONQCh. 3 - 13. A cell has four pairs of chromosomes. Assuming...Ch. 3 - 14. With regard to question C13, how would the...Ch. 3 - Eukaryotic cells must sort their chromosomes...Ch. 3 - Why is it necessary for the chromosomes to...Ch. 3 - Nine-banded armadillos almost always give birth to...Ch. 3 - 18. A diploid species has four chromosomes per set...Ch. 3 - 19. Explain why the products of meiosis may not be...Ch. 3 - The period between meiosis I and meiosis II is...Ch. 3 - 21. List several ways in which telophase appears...Ch. 3 - Corn has 10 chromosomes per set, and the...Ch. 3 - The arctic fox has 50 chromosomes (25 per set),...Ch. 3 - 24. Let’s suppose that a gene affecting...Ch. 3 - 25. Describe the cellular differences between male...Ch. 3 - 26. At puberty, the testes contain a finite number...Ch. 3 - Describe the timing of meiosis I and II during...Ch. 3 - 28. Three genes (A, B, and C) are found on three...Ch. 3 - A woman with an abnormally long chromosome 13 (and...Ch. 3 - Assuming that such a fly would be viable, what...Ch. 3 - 31. What would be the sex of a human with each of...Ch. 3 - When studying living cells in a laboratory,...Ch. 3 - 2. In Morgan’s experiments, which result do you...Ch. 3 - 3. In his original studies of Figure 3.18, Morgan...Ch. 3 - How would you set up crosses to determine if a...Ch. 3 - 5. Occasionally during meiosis, a mistake can...Ch. 3 - Lets suppose that you have made a karyotype of a...Ch. 3 - Prob. 7EQCh. 3 - 8. White-eyed flies have a lower survival rate...Ch. 3 - A rare form of dwarfism that also included hearing...Ch. 3 - 10. Discuss why crosses (i.e., the experiments of...Ch. 3 - Prob. 11EQCh. 3 - 12. Experimentally, how do you think researchers...Ch. 3 - 1. In Figure 3.18, Morgan obtained a white-eyed...Ch. 3 - 3. Discuss the principles of the chromosome theory...
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- Infants born with Patau syndrome have an extra copy of chromosome 13, which leads to developmental abnormalities such as cleft lip and palate, small eyes, and extra fingers and toes. Another type of genetic disorder, Turner syndrome, results from the presence of only one sex chromosome—an X chromosome. Individuals born with one X chromosome are females exhibiting few noticeable defects until puberty, when they fail to develop normal breasts and internal sexual organs. what is more information about these genetic diseases on how they relate and differ? What are the meiotic events that could lead to the birth of an individual with either Patau syndrome or Turner syndrome as shown above?arrow_forwardCystic fibrosis is a recessive disease that affects many parts of the body, but primarily presents itself through difficulty breathing and through cysts in the pancreas. It is caused by mutations in the gene CFTR. What chromosome is the gene on?arrow_forwardIn humans, chromosome 16 sometimes has a heavily stained area in the long arm near the centromere. This feature can be seen through the microscope but has no effect on the phenotype of the person carrying it. When such a “blob” exists on a particular copy of chromosome 16, it is a constant feature of that chromosome and is inherited. A couple conceived a child, but the fetus had multiple abnormalities and was miscarried. When the chromosomes of the fetus were studied, it was discovered that it had three copies of chromosome 16 (it was trisomic for chromosome 16), and that two of the three chromosome 16s had large blobs. Both chromosome 16 homologs in the mother lacked blobs, but the father was heterozygous for blobs. Which parent experienced nondisjunction, and in which meiotic division did it occur?arrow_forward
- In a sample of 1000 patients with Down syndrome, a geneticist discovers that 95% of them are trisomic, while 5% have diploid number of chromosomes. Explain this discrepancy.arrow_forwardFamilial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability and phenotype of the zygote. ✓ Two normal copies of 14, two normal copies of 21 two normal copies of 21, one normal copy of 14 ✓one normal copy of 14, one 21 to 14 translocation, one normal copy of 21 ✓two normal copies of 14, one normal copy of 21, on 21 to 14…arrow_forwardGiven the following genetic map, predict the chance an offspring would inherit the exact same haplotypes that the parents had. Assume interference in this area of the chromosome is 5%. Please report your value as a percent (%). A |-- 3 mu -- |-- 12 mu -- | Parent 1 Haplotypes: A1 B6 C14/A5 B1 C3 Parent 2 Haplotypes: A8 B3 C2 / A7 B2 C5arrow_forward
- A cytogeneticist has collected tissue samples from members of a certain butterfly species. Some of the butterflies were located in Canada, and others were found in Mexico. Through karyotyping, the cytogeneticist discovered that chromosome 5 of the Canadian butterflies has a large inversion compared with chromosome 5 of the Mexican butterflies. The Canadian butterflies were inversion homozygotes, whereas the Mexican butterflies had two normal copies of chromosome 5. 1) Would a cross between Mexican and Canadian butterflies produce phenotypically normal offspring? and 2) Would the offspring of the cross (so F2 generation) be fertile?arrow_forwardA cytogeneticist has collected tissue samples from members of acertain butterfly species. Some of the butterflies were located inCanada, and others were found in Mexico. Through karyotyping,the cytogeneticist discovered that chromosome 5 of the Canadianbutterflies had a large inversion compared with chromosome 5 ofthe Mexican butterflies. The Canadian butterflies were inversionhomozygotes, whereas the Mexican butterflies had two normalcopies of chromosome 5.Explain whether a mating between Canadian and Mexicanbutterflies would produce phenotypically normal offspring?arrow_forwardWe say that genes that are close together on the same chromosome are linked. What does that mean? Imagine that in a diploid nucleus, one chromosome has the allele R and right next to it on the same chromosome is the allele T for a different gene. Are these linked? Imagine that r is right next to t on the homologous chromosome. If this cell never undergoes meiosis, does this matter at all? If it does undergo meiosis, what are the two genotypes that the gametes are most likely to have? Look at Figure for help if you need it.arrow_forward
- On rare occasions, people are born with a condition known as uniparental disomy. It happens when an individual inherits both copies of achromosome from one parent and no copies from the other parent. Thisoccurs when two abnormal gametes happen to complement each otherto produce a diploid zygote. For example, an abnormal sperm thatlacks chromosome 15 could fertilize an egg that contains two copies ofchromosome 15. In this situation, the individual has maternal uniparental disomy 15 because both copies of chromosome 15 were inheritedfrom the mother. Alternatively, an abnormal sperm with two copies ofchromosome 15 could fertilize an egg with no copies. This is known aspaternal uniparental disomy 15. If a female is born with paternal uniparental disomy 15, would you expect her to be phenotypically normal,have Angelman syndrome (AS), or have Prader-Willi syndrome(PWS)? Explain. Would you expect her to produce normal offspring oroffspring affected with AS or PWS?arrow_forwardA phenotypically normal woman has an abnormally structured chromosome 2, along with a normal homologue. She marries a phenotypically normal man with an abnormally structured chromosome 16 and a normal homologue. What is the probability of their child will have an abnormal chromosome 2 and 16? What is the probability that this child, having inherited both abnormal chromosomes, will now pass both abnormal chromosomes to its children?arrow_forwardIn humans, chromosome 16 sometimes has a heavily stained area near the centromere. This feature can be seen in a microscope, but otherwise has no effect on the phenotype of the person carrying it. When such a “blob" exists on a given copy of chromosome 16, it is a constant feature of that chromosome and is inherited. A couple conceived a child, but the fetus had multiple abnormalities and was miscarried. e.g., The fetus had three copies of chromosome 16, where 2 of the 3 copies of chromosome 16 had large blobs. Both of the mother's copies of chromosome 16 lacked blobs, but the father was heterozygous for blobs. The fetus was formed from a fertilization event that included a gamete produced by the in which nondisjunction occurred during the meiotic division. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a mother; first. mother; second. father; first. C Your answer d father; second. E3 Fullso L e Insufficient information is provided…arrow_forward
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