The evidence shown in the table that will prove the hypothesis that A 2 , A 3 , B 23 , A 19 , and B 24 amino acids play an important role in the activity of insulin binding. . Introduction: Insulin is a 51-amino acid hormone that is required by the vertebrates for the regulation of blood glucose levels and affects lipid or protein metabolism . Thus, to some extent, affects the life span of an organism. It helps in the storage of excess glucose in the form of glycogen in the muscle tissues. It contains a quaternary structure in which two chains are held together by the disulfide bonds. Insulin performs its actions through binding as a monomer to the (αβ) 2 -homodimeric, tyrosine kinase-type insulin receptor (IR).

Question

Want to see the full answer?

Answer 1

Question

Chapter 3, Problem 2Q

Summary Introduction

To review:

The evidence shown in the table that will prove the hypothesis that A₂, A₃, B₂₃, A₁₉, and B₂₄ amino acids play an important role in the activity of insulin binding.

.

Introduction:

Insulin is a 51-amino acid hormone that is required by the vertebrates for the regulation of blood glucose levels and affects lipid or protein metabolism. Thus, to some extent, affects the life span of an organism. It helps in the storage of excess glucose in the form of glycogen in the muscle tissues. It contains a quaternary structure in which two chains are held together by the disulfide bonds. Insulin performs its actions through binding as a monomer to the (αβ)₂-homodimeric, tyrosine kinase-type insulin receptor (IR).

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

What does this important observation imply about the relation between the amino acid sequence of insulin and its three-dimensional structure?

What peptides are expected to be produced when the A chain of bovine insulin (Figure 5.16) is cleaved by (a) chymotrypsin, or (b) trypsin, or (c) carboxypeptidase A?

HbA1c is used to monitor blood glucose levels because hemoglobin is the only protein in blood that is covalently modified by glucose. True False Insulin Glargine is a long-acting form of insulin that is synthesized with several D-amino acids that slow its proteolytic degradation and extend the half-life of the insulin Glargine molecule. True False