Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 22, Problem 8E

(a)

Summary Introduction

To identify: The two reactions that allow the kidney to produce NH4+.

Concept introduction: Gluconeogenesis is a metabolic pathway that generates glucose from a non-carbohydrate carbon substance such as lactate, glycerol, and glucogenic amino acids. Kidney is the only tissue besides the liver that can carry out the glucose synthesis.

(b)

Summary Introduction

To identify: The gluconeogenic precursor generated in the kidney when it produces NH4+.

Concept introduction: Gluconeogenesis is a metabolic pathway that generates glucose from a non-carbohydrate carbon substance such as lactate, glycerol, and glucogenic amino acids. Kidney is the only tissue besides the liver that can carry out the glucose synthesis.

Summary Introduction

To describe: The pathway in which gluconeogenic precursor can be converted to glucose.

Concept introduction: Gluconeogenesis is a metabolic pathway that generates glucose from a non-carbohydrate carbon substance such as lactate, glycerol, and glucogenic amino acids. Kidney is the only tissue besides liver that can carry out the glucose synthesis.

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