Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 22, Problem 17E
Summary Introduction

To explain: The reason why PYY3-36 hormone must be administered intravenously rather than orally in the experiments to test the appetite-suppressing effects of PYY3-36.

Concept introduction: Peptide YY (PYY) is also known as peptide tyrosine. It is a peptide that is encoded by PYY gene in the humans. It is a short peptide having 36 amino acids and is released from the cells of ileum and colon in response to feeding. PYY3-36 and PYY1-36 are the two major forms of peptide YY. PYY3-36 is a linear polypeptide that consists of 34 amino acids.

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