Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 22, Problem 25PDQ
Some critics have warned that the use of gene therapy to correct genetic disorders will affect the course of human evolution. Evaluate this criticism in light of what you know about population genetics and evolution, distinguishing between somatic gene therapy and germ-line gene therapy.
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Match the current applications to the appropriate branch of genetics. Not all applications will be placed.
Hereditary genetics
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Population genetics
studying DNA-protein interactions
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researching gene transmission
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transmission within a family
Molecular genetics
studying the effects of natural
selection in many organisms
over the past million years
calculating genotype frequencies
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Genetics is commonly seen as being grouped into several general areas: transmission, molecular, and population/evolution. Which biological processes are studied in transmission genetics?
Write a paragraph describing the evolutionary forces driving changes in the human genome. You can include evolutionary forces such as random genetic drift, mutation, migration, and natural selection. These forces would have long-term and short-term effects on coding and non-coding DNA, the abundance of transposable elements, and the birth and death of genes. You can focus on a subset of the human population, or the entire species.
Chapter 22 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 22 - CASE STUDY |An unexpected outcome A newborn...Ch. 22 - CASE STUDY |Anunexpected outcome A newborn...Ch. 22 - CASE STUDY|An unexpected outcome A newborn...Ch. 22 - HOW DO WE KNOW? Population geneticists study...Ch. 22 - Review the Chapter Concepts on page 441. All these...Ch. 22 -
3. Price et al. (1999. J. Bacteriol. 181:...Ch. 22 -
4. The genetic difference between two Drosophila...Ch. 22 - The use of nucleotide sequence data to measure...Ch. 22 - Calculate the frequencies of the AA, Aa, and aa...Ch. 22 - Prob. 7PDQ
Ch. 22 -
8. What must be assumed in order to validate the...Ch. 22 - In a population where only the total number of...Ch. 22 -
10. If 4 percent of a population in equilibrium...Ch. 22 -
11. Consider a population in which the frequency...Ch. 22 - If the initial allele frequencies are p = 0.5 and...Ch. 22 -
13. Under what circumstances might a lethal...Ch. 22 - Assume that a recessive autosomal disorder occurs...Ch. 22 -
15. One of the first Mendelian traits identified...Ch. 22 -
16. Describe how populations with substantial...Ch. 22 - Achondroplasia is a dominant trait that causes a...Ch. 22 -
18. A recent study examining the mutation rates...Ch. 22 - A form of dwarfism known as Ellis–van Creveld...Ch. 22 -
20. List the barriers that prevent interbreeding...Ch. 22 - What are the two groups of reproductive isolating...Ch. 22 - Prob. 22PDQCh. 22 -
23. In a recent study of cichlid fish inhabiting...Ch. 22 - What genetic changes take place during speciation?Ch. 22 - Some critics have warned that the use of gene...Ch. 22 - Comparisons of Neanderthal mitochondrial DNA with...
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- The human genome has been fully mapped by the Human Genome Project. Information on the human genome is now freely available on DNA databases. Which statement best describes an ethical issue concerning the Human Genome Project? Responses The money invested in this project can be utilized for other research. The money invested in this project can be utilized for other research. The complete information about the human genome can be utilized to map human ancestry. The complete information about the human genome can be utilized to map human ancestry. The complete information about the human genome can lead to devastating consequences on Earth’s biodiversity. The complete information about the human genome can lead to devastating consequences on Earth’s biodiversity. The human genome will provide information about inherited diseases, which raises the possibility of genetic manipulation in individuals.arrow_forwardBIOLOGY Give the SCOPE of the following fields in Applied Genetics: (SCOPE, not definition) 1. Epigenetics 2. Genomics 3. Metagenics 4. Genetic engineering 5. Phylogeneticsarrow_forwardDiscuss the impact of genetics in modern society. Cite specific examples.arrow_forward
- Give the scope of the following fields in Applied Genetics: Epigenetics Genomics Genetic Engineering Phylogenetics Metagenics take note that SCOPE is what I'm askingarrow_forwardGive a schematic diagram of how we can Treatment Down Syndrome by using gene therapy? Please answer at your own words,please..arrow_forwardIf you had the ability to do gene editing with ONE gene for the betterment of human kind, which one would you choose, and why? Assume you could either change an abnormal allele associated with a disease, such as the cystin gene associated with Cystic Fibrosis to its normal wild type, or add a pre-existing human allele to a genome.arrow_forward
- A.) Write a paragraph discussing the approach you would take to create a transgenic organism and the drawbacks to creating it. B.) Write comprehensively your answer about sequence events leading to evolution by natural selection.arrow_forwardFor each pair of individuals listed in the left column, select the description which best details the pair's contribution to genetics. 1. one gene - one enzyme hypothesis Beadle and Tatum 2. formula for the chance distribution of genotypes in natural populations Hardy and Weinberg 3. bacterial operons Jacob and Monod 4. phenomenon of sex linkagearrow_forwardBioinformatics is an interdisciplinary field that integrates knowledge of computer science with mathematics and statistics to solve biological questions. Many bioinformatics tools for gene prediction, homology modelling and such are available free online. (1) What does BLAST stand for? (ii) Explain the function of BLAST.arrow_forward
- Genetic engineering utilized to create food sources has been said to be both like and unlike traditional breeding. One way it is different is: It mixes genes from different individuals of the same or similar species It involves whole organisms living in the field It selects from combinations of genes that come together on their own It mixes genes of different organisms such as viruses and crops, or spiders and goatsarrow_forwardYou are discussing with some of your bio major friends who have not taken Genetics and your non-bio major friends about how characteristics such as blue eye, light skin pigmentation, and light hair color, derived from a mutation that occurred about 10,000 years ago in Europe. Your friends are not very happy that you used the word mutation to describe the origin of human characteristics associated with light pigmentation. At that moment you only recall that green eye, fair skin and red hair in Neanderthals was due to other alleles and you mention that to them as an example of genetic determinants in species of the genus Homo. They are not convinced of your choice of the word mutation. Then you remember part of one of the papers that you read for Minicourse 5 regarding the OCA2 allele. “OCA2, homologous to the mouse pink-eyed dilution gene, encodes the human protein P, an integral membrane protein involved in both the transport of tyrosine and that helps in the regulation of…arrow_forwardThe Human Genome Project has demonstrated that in humans of all races and nationalities approximately 99.9 percent of the sequence is the same, yet different individuals can be identified by DNA fingerprinting techniques. What is one primary variation in the human genome that can be used to distinguish different individuals? Briefly explain your answer.arrow_forward
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