Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 2, Problem 47P
The accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information.
a. Using A for the dominant allele and a for the recessive allele, give the genotypes for I-1, I-2, and II-1.
b. Using the same alleles, give the possible genotypes for II-2, II-3, and II-4.
c. What are the probabilities for each of the possible genotypes for II-2, II-3, and II-4?
d. What is the probability that all three of the children in generation II who have the dominant
e. What is the chance that among the three children in generation II who have the dominant phenotype, one of them is AA and two of them are Aa? (Hint: Consider all possible orders of genotypes.)
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Students have asked these similar questions
The pedigree shows inheritance of the autosomal recessive trait cystic fibrosis in a family. Family members who are
known to have the disease are represented by black shading.
I
1
2
3
4
II 1
3
4
6
8
7
III
1
2
3
4
5
6
7
Part A: Select the best answer from the boxes below to indicate the likely genotypes of the following individuals, where F
indicates the wild-type (usual) allele and f indicates the cystic fibrosis allele. The first part of their number (I, II or III)
indicates their generation or row, whilst the second part of their number (1-8) indicates the individual within that generation
or row.
|-4
Il-3
Il-8
III-3
Using the pedigree, assume that the disease is caused by an autosomal dominant allele, R. Give the genotype of the following individuals:
(a) III-4 (the girl at lower right)
(b) II-3 (the girl’s mother)
(c) II-4 (the girl’s father)
Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele. Assume complete penetrance.
I
II
III
3
IV
1
2
a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no.
(i) an autosomal recessive allele (AR)
(ii) an autosomal dominant allele (AD)
(iii) a X-linked recessive allele (XR)
(iv) a X-linked dominant allele (XD)
b. Based strictly on the characteristic patterns of inheritance that define the four different options in (a), give a definitive motivation for the most likely mode of
inhertance.
Chapter 2 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 2 -
1. Compare and contrast the following terms:
a....Ch. 2 - For the cross , what is the expected genotype...Ch. 2 - 37. Galactosemia is an autosomal recessive...Ch. 2 - In mice, black coat color is dominant to white...Ch. 2 - Two parents plan to have three children. What is...Ch. 2 - Consider the cross AaBbCCAABbCc. a. How many...Ch. 2 - If a chi-square test produces a chi-square value...Ch. 2 -
8. Determine whether the statements below are...Ch. 2 - In the datura plant, purple flower color is...Ch. 2 - 10. The dorsal pigment pattern of frogs can be...
Ch. 2 - 11. Black skin color is dominant to pink skin...Ch. 2 - A male mouse with brown fur color is mated to two...Ch. 2 - 13. Figure 2.12 shows the results of Mendel’s...Ch. 2 - 14. An experienced goldfish breeder receives two...Ch. 2 -
15. The accompanying pedigree shows the...Ch. 2 -
16. A geneticist crosses a pure-breeding strain...Ch. 2 - Suppose an F1 plant from Problem 16 is crossed to...Ch. 2 - 18. In pea plants, the appearance of flowers along...Ch. 2 - 19. If two six-sided dice are rolled, what is the...Ch. 2 - Experimental Insight 2.1 describes data, collected...Ch. 2 -
21. The accompanying pedigree shows the...Ch. 2 - 22. The seeds in bush bean pods are each the...Ch. 2 - List all the different gametes that are possible...Ch. 2 - Organisms with the genotypes AABbCcDd and AaBbCcDd...Ch. 2 - 25. Blue moon beans produce beans that are either...Ch. 2 - In the fruit fly Drosophila, a rudimentary wing...Ch. 2 - In pea plants, plant height, seed shape, and seed...Ch. 2 - A variety of pea plant called Blue Persian...Ch. 2 - 29. In tomato plants, the production of red fruit...Ch. 2 - A male and a female are each heterozygous for both...Ch. 2 - A woman expressing a dominant phenotype is...Ch. 2 - Two parents who are each known to be carriers of...Ch. 2 - 33. An organism having the genotype AaBbCcDdEe is...Ch. 2 - 34. A man and a woman are each heterozygous...Ch. 2 - For a single dice roll, there is a 16 chance that...Ch. 2 - You have four guinea pigs for a genetic study. One...Ch. 2 - 37. Galactosemia is an autosomal recessive...Ch. 2 - Sweet yellow tomatoes with a pear shape bring a...Ch. 2 - A cross between a spicy variety of Capsicum annum...Ch. 2 - Alkaptonuria is an infrequent autosomal recessive...Ch. 2 - 41. Humans vary in many ways from one another....Ch. 2 - 42. In chickens, the presence of feathers on the...Ch. 2 -
43. A pure-breeding fruit fly with the...Ch. 2 - 44. Situs inversus is a congenital condition in...Ch. 2 - 45. Domestic dogs evolved from ancestral grey...Ch. 2 - Alleles of the IGF-1 gene in dogs, encoding...Ch. 2 - 47. The accompanying pedigree shows a family in...Ch. 2 -
48. A pea plant that has the genotype RrGgwwdd is...Ch. 2 - Go to the OMIM website...Ch. 2 - Prob. 50PCh. 2 - Prob. 51PCh. 2 -
52. In humans, the ability to bend the thumb...
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