Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN: 9781285866932
Author: Lauralee Sherwood
Publisher: Cengage Learning
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Chapter 2, Problem 3SQE
Summary Introduction
To calculate:
The number of calories produced per day in the form of ATP by a resting individual.
Introduction:
ATP is also known as Adenosine triphosphate. It is a molecule which stores energy within cells and is the chief energy currency of the cell. It is the final product of the processes of photophosphorylation,
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Walking consumes approximately 100 kcal/mi. In the hydrolysis of ATP (ATP → ADP + Pi), the reaction that drives muscle contraction, ΔG°′ is −7.3 kcal/mol (−30.5 kJ/mol). Calculate how many grams of ATP must be produced to walk a mile. ATP synthesis is coupled to the oxidation of glucose (ΔG°′ = −686 kcal/mol). How many grams of glucose are actually metabolized to produce this amount of ATP? (Assume that only glucose oxidation is used to generate ATP and that 40% of the energy generated from this process is used to phosphorylate ADP. The gram molecular weight of glucose is 180 g and that of ATP is 507 g.)
If the DGo for ATP hydrolysis into ADP + inorganic phosphate is -7.3 kcal/mole, and the DGo for sucrose synthesis from glucose + fructose is +5.5 kcal/mole, calculate standard free energy change for the combined reaction of ATP + glucose + fructose g ADP + sucrose + inorganic phosphate.
DGo = -12.8 kcal/mole
DGo = -1.8 kcal/mole
DGo = 0 kcal/mole
DGo = +1.8 kcal/mole
DGo = +12.8 kcal/mole
B) The actual concentrations of ATP, ADP and Pi differ by tissue/cell type (see table).
Tissue/Cell Type
ATP (mM)
ADP (mM)
Pi (mM)
Liver
3.5
1.8
5.0
8.0
2.7
Skeletal Muscle
8.0
0.9
Brain
2.6
0.7
Calculate AG' for ATP hydrolysis in liver. (NOTE: assume 25°C and omit the concentration of
water in your calculations).
Chapter 2 Solutions
Human Physiology: From Cells to Systems (MindTap Course List)
Ch. 2.1 - State the principles of the cell theory.Ch. 2.1 - Prob. 2CYUCh. 2.2 - State the functions of DNA and the different types...Ch. 2.2 - Prob. 2CYUCh. 2.2 - Prob. 3CYUCh. 2.3 - Prob. 1CYUCh. 2.3 - Discuss the structure and function of a ribosome.Ch. 2.3 - Prob. 3CYUCh. 2.3 - Prob. 4CYUCh. 2.4 - Describe the structure and functions of a Golgi...
Ch. 2.4 - Prob. 2CYUCh. 2.4 - Prob. 3CYUCh. 2.5 - Prob. 1CYUCh. 2.5 - Prob. 2CYUCh. 2.5 - Prob. 3CYUCh. 2.6 - Prob. 1CYUCh. 2.6 - Prob. 2CYUCh. 2.7 - Prob. 1CYUCh. 2.7 - Prob. 2CYUCh. 2.7 - Prob. 3CYUCh. 2.7 - Prob. 4CYUCh. 2.8 - Prob. 1CYUCh. 2.8 - Prob. 2CYUCh. 2.9 - Prob. 1CYUCh. 2.9 - Prob. 2CYUCh. 2.10 - List the three types of cytoskeletal elements and...Ch. 2.10 - Explain how motor proteins transport proteins...Ch. 2.10 - Prob. 3CYUCh. 2.10 - Prob. 4CYUCh. 2 - Prob. 1RECh. 2 - Prob. 2RECh. 2 - Prob. 3RECh. 2 - Prob. 4RECh. 2 - Prob. 5RECh. 2 - Prob. 6RECh. 2 - Prob. 7RECh. 2 - Prob. 8RECh. 2 - Prob. 9RECh. 2 - Using the answer code on the right, indicate which...Ch. 2 - Prob. 11RECh. 2 - Prob. 1UCCh. 2 - Prob. 2UCCh. 2 - Prob. 3UCCh. 2 - Compare exocytosis and endocytosis. Define...Ch. 2 - Prob. 5UCCh. 2 - Compare lysosomes with peroxisomes.Ch. 2 - Distinguish among cellular respiration, oxidative...Ch. 2 - Prob. 8UCCh. 2 - Prob. 9UCCh. 2 - Cells expend energy on what three categories of...Ch. 2 - Prob. 11UCCh. 2 - Prob. 1SQECh. 2 - Prob. 2SQECh. 2 - Prob. 3SQECh. 2 - Calculate the number of cells in the body of an...Ch. 2 - Prob. 5SQECh. 2 - Applying Clinical Reasoning Kevin S. and his wife...Ch. 2 - The stomach has two types of exocrine secretory...Ch. 2 - Prob. 2TAHLCh. 2 - Prob. 3TAHLCh. 2 - Why do you think a person is able to perform...Ch. 2 - Prob. 5TAHL
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