Applying Clinical Reasoning
Kevin S. and his wife have been trying to have a baby for the past 3 years. On seeking the help of a fertility specialist, Kevin learned that he has a hereditary form of male sterility involving nonmotile sperm. His condition can be traced to defects in the cytoskeletal components of the sperm’s flagella. As a result of this finding, the physician suspected that Kevin also has a long history of recurrent respiratory tract disease. Kevin confirmed that indeed he has had colds, bronchitis, and influenza more frequently than his friends. Why would the physician suspect that Kevin probably had a history of frequent respiratory disease based on his diagnosis of sterility from nonmotile sperm?
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Human Physiology: From Cells to Systems (MindTap Course List)
- Answer these questions: 1. During what phase of the cell cycle does DNA replication occur? 2. During mitosis, at what phase do chromosomes first become visible? 3. During what 2 phases of mitosis are chromosomes each composed of two chromatids? 4. During what 2 phases of mitosis are chromosomes each composed of one chromatid? 5. How does cytokinesis differ in plants and animals? 6. What is the term used to refer to the "division of the cytoplasm"? 7. Are the two cells created from mitosis the genetically identical or different? 8. Write the stages of the cell's life cycle in order, starting with the stage immediately after cytokinesis.arrow_forwardCell specializations are usually a modification or elaboration of one of the basic cell functions. (True or fa1se?)arrow_forwardThe procedure for determining vitality is to place sperm in a hypotonic solution and observe the specimen under the microscope after a 5-minute incubation. This short incubation time allows for observable cellular changes without causing cell death. What type of microscope (light or electron) would you recommend using to observe sperm cells for this laboratory test and why?arrow_forward
- Q/Choose between parentheses 1-the cell cycle included three phases are........ * (interphase,Mitosis,Cytokinesis/ Mitosis, interphase, cytokinesis/ cytokinesis , interphase , Mitosis/ interphase ,prophase, cytokinesis, metaphase) 2-What the name of structure is plays a significant role in the internal organization of the cell by synthesizing selective molecules and processing, directing and sorting them to their appropriate locations. * (Endoplasmic Reticulum/Mitochondria/Golgi bodies/ Rough Endoplasmic Reticulum) 3-cell membrane formed of .................phospholipid * (bilipid layer/one lipid layer/ tri lipid layer/four lipid layer)arrow_forward- - da a Lenuar UVIUI IS UIE UI Ue processes that support the Cell theory. Consider Figure 1 as eukaryotic cell and to be referred in this question. Figure 1 a) Based on Figure 1, does the cell represent a gamete cell? Justify your answer. b) State the value of 2n in Figure 1. c) Using a labelled diagram, ilustrates the cell in Figure 1 after t undergoes S stage. d) If cell in Figure 1 experienced a non-disjunction event on its largest chromosomes during meiosis 2, illustrates the probable gametes it produces using a labelled diagram. e) Give the probabity percentage for each type of gamete produced in 2d). f) Does cell division in E col and in human cells serves the same purpose? Justify your answer.arrow_forwardCancer cells can eventually metastasize (or spread) from their tissue of organ to distant sites throughout the body. Which of the three types of cytoskeletal components could be used to detect the tissue of organ of a metastatic cancer cell? Why? (For example, if you took a biopsy of a tumor that had spread to the lungs, how could use what you know about the cytoskeleton to determine where the cancer originated? )arrow_forward
- In order to investigate the cell cycle in HEK293 cells in culture, I ran a flow cytometry experiment. I labeled their nuclei with DAPI to analyze DNA content. In these flow cytometry plots below, label the two main phases of the cell cycle that you can see. Briefly, explain your answer.arrow_forwardThe following image shows the basic cross sectional structure of a 9 + 2 array in a microtubule. The two images below it show cross sections of the microtubule flagellum of sperms cells from a man affected by Kartagener syndrome and an unaffected man. Examine these images, then answer the questions that follow. What structure appears to be underdeveloped or missing in the microtubules of the sperm flagellum affected by Kartagener syndrome? A. Pairs of microtubules B. The dynein "arms" C. The plasma membranearrow_forwardA cell with one mutation is unable to complete cell division (mitosis). What intracellular structure/structures might be defective? Explain your answer by first giving the normal role of this/these structures and then explaining why when defective, it/they might prevent the cell from completing mitosis.arrow_forward
- As a sperm cell finally approaches its final target, its acrosome becomes activated. The acrosome is a specialized organelle found in the cell’s head region and activation results in the exocytosis of several types of proteolytic enzymes. Name 2 specific proteins you might expect the enzymes released by the acrosome to breakdown. What purpose does this play in the fertilization of the egg? Explain your reasoning.arrow_forwardIn this picture what is happening during step 1 to create the cell in the middle. You can answer with the specific name of the process or by describing what is happening. eg9 Step 1 Step 2 Fully grown multicellular organism sperm (level 2) Ctv MacBook Air 888 F10 FS F2 & 23 2$ 8 9. 3 4 { E R Y D G J K C V command option レレ リ .. •- • V Barrow_forwardChemotherapy drugs such as vincristine and colchicines disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Explicitly referring to Mitosis, explain what mitotic structure is targeted by these drugs, and what effect would this have on cell division?arrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning