Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 19, Problem 7QP
How Can We Measure Allele Frequencies in Populations?
Drawing on your newly acquired understanding of the Hardy–Weinberg equilibrium law, point out why the following statement is erroneous: “Because most of the people in Sweden have blond hair and blue eyes, the genes for blond hair and blue eyes must be dominant in that population.”
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Nieman-Pick Syndrome involves a defective enzyme, sphyngomylinase. It is usually fatal before the age of 3. The defective allele frequency is 0.01 in Ashkenazi populations. Let’s call the healthy allele A, and the lethal allele a.
a) What is the frequency of allele A?
Assuming Hardy-Weinberg equilibrium, how many people do you expect to have the three genotypes in a population of 10,000?
b) AA:_______
c) Aa:________
d) aa:_________
Assume that the frequency of gene B in a hypothetical population Is 0.63, that there are only two alleles (B and b) of the gee in the population, that allele B is dominant over allele b, that neither allele has a selective advantage over the other, and that the population is at equilibrium with regard to this particular gene. And how many individuals in this population are expected to be of genotype BB according to the Hardy-Weinberg formula? (Assume that the total population size is 150)
71
52
118
60
131
A) Explain why we use the concept of Hardy-Weinberg Equilibrium if populations are never stable?
B) What do the mathematical results tell us if the allele frequencies do not match our predictions?
(In other words, if you have extra spotted fish in a generation, what has happened?)
Chapter 19 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 19.8 - Why dont genetic markers on the Y chromosome...Ch. 19.8 - Prob. 2GRCh. 19 - If you suspected that heterozygous carriers of a...Ch. 19 - If allele frequencies in the hemoglobin gene are...Ch. 19 - Prob. 1QPCh. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - Prob. 4QPCh. 19 - Prob. 5QPCh. 19 - How Can We Measure Allele Frequencies in...
Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - Using the HardyWeinberg Law in Human Genetics...Ch. 19 - Prob. 10QPCh. 19 - Using the HardyWeinberg Law in Human Genetics In a...Ch. 19 - Prob. 12QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Prob. 15QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Prob. 17QPCh. 19 - Prob. 18QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Natural Selection Affects the Frequency of Genetic...Ch. 19 - Prob. 21QPCh. 19 - Prob. 22QPCh. 19 - The Evolutionary History and Spread of Our Species...Ch. 19 - Prob. 24QPCh. 19 - Genomics and Human Evolution The Denisovan genome...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In corn, kernel color is governed by a dominant allele for white color (W) and by a recessive allele for yellow (w). A random sample of 152 kernels from a population that is in Hardy- Weinberg equilibrium reveals that 35 kernels are yellow and 117 kernels are white. What is the frequency of individuals with the homozygous dominant genotype?arrow_forwardThere are two existing hypotheses for an unusually high frequency of a deleterious recessive allele in a certain population other than it is hidden in the heterozygous genotype and not exposed to selection. Explain what these two likely hypotheses are and how you could distinguish between them based on your understanding of the applicable assumptions that are part of the Hardy-Weinberg Equilibrium Modelarrow_forwardIf a population is in Hardy-Weinberg equilibrium for the multiple alleles A+, A and a, whose frequencies are p= 0.60 for A+, q= 0.20 for A, and r = 0.20 for a, what percentage of the population is expected to be heterozygous?arrow_forward
- In a population of 200 people, an allele F has a frequency of 84%. What is the frequency of allele f? Using the Hardy-Weinberg equation, estimate the numbers of homozygous dominant, heterozygous, and homozygous recessive genotypes. (Remember that the formula is: p2 + 2pq + q2 = 1, where p represents the dominant allele and q represents the recessive allele.) *Be sure to account for all 200 people in the population.arrow_forwardAn autosomal locus has alleles A and a. The allele frequencies in a population at Hardy Weinberg equilibrium are p = Freq(A) = 0.5 q = Freq(a) = 0.5 What is the frequency of homozygous wild-type (AA) in this population? Enter a single number between 0 and 1, for example, 0.33arrow_forwardThe ability to taste the compound PTC is controlled by a dominant allele T, while individuals homozygous for the recessive allele (t) cannot taste PTC. In a population consisting of 500 individuals, 347 are tasters and 153 are non-PTC tasters. Calculate the frequency of the T and t alleles in this population, and frequency of the genotypes. (Please train yourself to use the Hardy-Weinberg equation.)arrow_forward
- A sample of 100 individuals from a population that is dimorphic at the A locus has genotype counts as follows. AA: 30 Aa: 60 aa: 10 a) What are the allele frequencies in the population? b) What are the expected genotype frequencies, if the population were at HardyWeinberg equilibrium? c) Is the proportion of heterozygotes lower or higher than expected at Hardy-Weinberg equilibrium? What deviations from the assumptions of the model would best explain the observed difference?arrow_forwardConsider the B locus which has two alleles in a population: B and b. Researchers examined the genotypes several individuals for this locus and obtained the following numbers B/B: 302individuals B/b: 56individuals b/b: 17individuals If the B locus is at Hardy-Weinberg equilibrium, what would the expected number of individuals with the Bb genotype? Round your answer to the closest full number.arrow_forwardIn monkeys, black coat color (B) is dominant over brown color (b). A population of monkeys was found to be composed of 67 brown coated individuals and 119 black coated individuals. Based upon the Hardy‑Weinberg formula, what proportion of the population is expected to have the genotype BB? Based upon the Hardy‑Weinberg formula, what proportion of the population is expected to bave black coat color?arrow_forward
- Pretend that you are comparing the actual genotype distribution for a population with the distribution of genotypes predicted by the Hardy-Weinberg theorem. So your hypothesis is that the population is in Hardy-Weinberg equilibrium (i.e. that actual population data fit the Hardy-Weinberg expectations). If you carry out a chisquare goodness of fit test and calculate a total chisquare value of 0.03 with 1 degree of freedom (see table), what does this mean? (select all true statements)a) The data do NOT fit the hypothesized distribution.b) The data do fit the hypothesized distribution well enough, so we accept the hypothesis at this time (i.e. we cannot reject the hypothesis). c) The probability that the data came from a population in Hardy-Weinberg equilibrium is too small, so we reject the hypothesis.d) The probability that the data came from a population in Hardy-Weinberg equilibrium is too big, so we reject the hypothesis.e) The data support Hardy-Weinberg expectations – there is no…arrow_forwardIn corn, yellow kernel color is governed by a dominant allele for white color, W, and by its recessive allele, w, . A random sample of 100 kernels from a population that is in equilibrium reveals that 9 are yellow and 91 are white. What are the frequencies of the yellow and white alleles in this population? What is the percentage of the heterozygotes?arrow_forwardConsider an autosomal locus with alleles A and a. If the the allele frequencies are as follows Freq(A) = 0.4, Freq(a) = 0.6. , then what is the predicted frequency of heterozygous Aa individuals, assuming the population is in Hardy-Weinberg equilibrium? Freq(Aa) = ? Enter a number between 0 and 1, inclusive, for example 0.33arrow_forward
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