Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 19, Problem 7QP

How Can We Measure Allele Frequencies in Populations?

Drawing on your newly acquired understanding of the Hardy–Weinberg equilibrium law, point out why the following statement is erroneous: “Because most of the people in Sweden have blond hair and blue eyes, the genes for blond hair and blue eyes must be dominant in that population.”

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Nieman-Pick Syndrome involves a defective enzyme, sphyngomylinase. It is usually fatal before the age of 3. The defective allele frequency is 0.01 in Ashkenazi populations. Let’s call the healthy allele A, and the lethal allele a. a) What is the frequency of allele A? Assuming Hardy-Weinberg equilibrium, how many people do you expect to have the three genotypes in a population of 10,000? b) AA:_______     c) Aa:________   d) aa:_________
Assume that the frequency of gene B in a hypothetical population Is 0.63, that there are only two alleles (B and b) of the gee in the population, that allele B is dominant over allele b, that neither allele has a selective advantage over the other, and that the population is at equilibrium with regard to this particular gene. And how many individuals in this population are expected to be of genotype BB according to the Hardy-Weinberg formula? (Assume that the total population size is 150) 71 52 118 60 131
A) Explain why we use the concept of Hardy-Weinberg Equilibrium if populations are never stable? B) What do the mathematical results tell us if the allele frequencies do not match our predictions? (In other words, if you have extra spotted fish in a generation, what has happened?)
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