Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 19, Problem 12QP
Summary Introduction
To determine: The allele frequencies when a trait is determined by autosomal recessive allele and occurs at a the frequency of 0.25 in population.
Introduction: The Hardy-Weinberg law states that in the absence of other evolutionary factors. the frequency of allele and genotypes or
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Connection to Quantitative traits: SNPs are inherited in a Mendelian fashion and are often polygenic in nature. We can think of SNPs in terms of either contributing or non-contributing alleles. A study of SNPs correlated with heart disease has shown that heart problems are severe if 9 or more of the alleles at 6 loci are of the contributing variety. What is the probability the following parents will have a child that is susceptible heart disease?
AaBbccDDEEFf x AaBbCCDdEeff
Suppose there is an autosomal locus of 2 alleles, A1 and A2, with probabilities (frequencies) p1 and p2, and the genotype probabilities (frequencies) are P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2, respectively. Prove the Hardy-Weinberg Law, i.e., after one generation of random mating, the genotype probabilities (frequencies) in the offspring are also P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2. Hint: List all possible combinations of random mating. Then list the probabilities of the resulting genotype probabilities (frequencies) in the offspring. Combine the probabilities of random mating and resulting genotype probabilities (frequencies) in the offspring.
Help me please
Chapter 19 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 19.8 - Why dont genetic markers on the Y chromosome...Ch. 19.8 - Prob. 2GRCh. 19 - If you suspected that heterozygous carriers of a...Ch. 19 - If allele frequencies in the hemoglobin gene are...Ch. 19 - Prob. 1QPCh. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - Prob. 4QPCh. 19 - Prob. 5QPCh. 19 - How Can We Measure Allele Frequencies in...
Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - Using the HardyWeinberg Law in Human Genetics...Ch. 19 - Prob. 10QPCh. 19 - Using the HardyWeinberg Law in Human Genetics In a...Ch. 19 - Prob. 12QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Prob. 15QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Prob. 17QPCh. 19 - Prob. 18QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Natural Selection Affects the Frequency of Genetic...Ch. 19 - Prob. 21QPCh. 19 - Prob. 22QPCh. 19 - The Evolutionary History and Spread of Our Species...Ch. 19 - Prob. 24QPCh. 19 - Genomics and Human Evolution The Denisovan genome...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?arrow_forwardIf a trait determined by autosomal recessive allele occurs at a frequency of 0.25 in a population, what are the allelic frequencies? Assume Hardy-Weinberg equilibrium and use A and a to symbolize the dominant and recessive alleles, respectively. Show calculation.arrow_forwardThe following genetic map describes three hypothetical human autosomal genes, each of which exhibits two alleles. Two-factor map distances are shown. A = Artistic (dominant) a = Inartistic (recessive) M = Moral (dominant) m = Immoral (recessive) G = Generous (dominant) g = Greedy (recessive) Assume that these traits exhibit simple Mendelian dominance/recessiveness. The coefficient of coincidence for this map is 0.4. An artistic, moral, generous heterozygous female of genotype AMG/amg marries an inartistic, immoral, greedy homozygous male of genotype amg/amg. What is the probability that their firstborn child will be inartistic, immoral and greedy? What is the probability that their firstborn child will be inartistic, moral and generous? What is the probability that their firstborn child will be artistic, immoral and generous?arrow_forward
- If a trait determined by an autosomal recessive allele occurs at a frequency of 0.25 in a population, what are the the allelic frequencies? Assume Hardy-Weinberg equilibrium and use A and a to symbolize the dominant and recessive alleles, respectively.arrow_forwardUsing the example of pea color in Mendel’s pea plants, can you devise equations to determine the allele frequencies of A and a from the genotype frequencies of aa, Aa, and AA?arrow_forwardA pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?arrow_forward
- The incidence of a rare autosomal recessive genetic disorder, Tay-Sachs, is approximately 1 in 3,500 in a certain population. Assuming that this population is in Hardy-Weinberg equilibrium, what is the probability that a phenotypically normal female with no family history, and a phenotypically normal male who had an affected great-aunt, will have a child who is a carrier for Tay-Sachs?arrow_forwardIn roan bulls, alleles for both red and white hair are codominant (BRBW). What is the percentage of genotype and phenotype if a roan cattle is bred to, (a) a homozygous red cow (BRBR), (b) a heterozygous white cow (BWBw).arrow_forwardIn a population of 1000 individuals, 180 have kinky hair, 360 have wavy hairy, and the rest have straight hair. Let us assume that hair type is governed by a pair of alleles, and there are two types of alleles, S (kinky) and s (straight), with the heterozygote condition being wavy. Compute for the allelic frequencies for hair type in the population. Albinism is a rare genetic condition, occurring in only one in every 17,000 to 22,000 individuals in the world (Campbell et al. 2003; Gronskov et al. 2007). a. What can you conclude about the allelic frequency of the a allele globally? b. Where do you think the a allele would be more commonly found, among the heterozygotes (Aa) or the homozygote recessives (aa)? Why do you say so?arrow_forward
- Instruction: Fill up the table by computing the dominant alleles, recessive alleles and the Hardy-Weinberg equilibrium result of each generation. Lastly, make a short conclusion below. Show the complete solution. Hardy-Weinberg Equilibrium Generation Dominant allele Recessive allele 1 35 65 2 50 50 3 73 27 Conclusion:arrow_forwardMendel's concept of dominance states that in a genotype where two different alleles of a locus are present, only the trait encoded by the dominant allele is observed. Give a molecular explanation for dominance, i.e. explain intracellular molecular events that can result in what we observe as dominance on a phenotypic level. Use the gene that encodes seed shape in peas as an example, where roun(R) is dominant over wrinkled(r), to explain how RR and Rr plants can have the same phenotype.arrow_forwardIn a population of 1000 individuals, 180 have kinky hair, 360 have wavy hairy, and the rest have straight hair. Let us assume that hair type is governed by a pair of alleles, and there are two types of alleles, S (kinky) and s (straight), with the heterozygote condition being wavy. Compute for the allelic frequencies for hair type in the population. Albinism is a rare genetic condition, occurring in only one in every 17,000 to 22,000 individuals in the world (Campbell et al. 2003; Gronskov et al. 2007). a. What happens to an individual who is albino (aa) or who has very low or lacks melanin pigments in the hair, skin and eyes? b. Based on your answer in c, how would you explain the frequency of the a allele?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
What is Evolution?; Author: Stated Clearly;https://www.youtube.com/watch?v=GhHOjC4oxh8;License: Standard Youtube License