Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 19, Problem 19PDQ
Summary Introduction
To review:
The reason for genetic analysis of the genome of the killer involved in tragic shooting of 20 children in New town, Connecticut. And what conclusions investigators want to draw about the killer and the tragedy.
Introduction:
This tragic shooting was the case of a psycho killer who killed 20 children of a school in 2012 in New Town, Connecticut. The killer Lanza entered the school in the early hours and started continuous firing on the school children. The killer Lanza also died in this tragedy. Several types of genetic analysis tests were carried out on a killer’s genome to know the possible reasons for this deadly event.
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b) Mr. Jason has received an identification card regarding his complete genome.
(1) biotechnology tool to develop a complete genome data.
Based on answer b (i). justify the advantages and disadvantages of having a complete genotype card?
1. a) If you were at risk of a fatal disease such as Huntington’s disease and only the 95% accurate preliminary genetic test was available, would you take the test? After all, 95% of the time the test would tell you whether you would eventually get Huntington’s disease or whether you did not have to worry about getting this disease.
b) The linkage distance between the DNA sequence used in the test and the actual Huntington’ disease locus was 5%. In a large sample of the Venezuelan family, what percentage of people would inherit the DNA sequence but not the Huntington’s allele (i.e. be a false positive test for Huntington’s)? What percentage of that large Venezuelan family would not inherit the DNA sequence but would inherit the Huntington’s allele (i.e., be a false negative test for Huntington’s)?
Pick one (1) of the five (5) principles developed by the Ethics Committee for the Human Genome Organization that must be considered when the global community is confronted by new technology. Why do you feel that principle is MOST important.
Chapter 19 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 19 - CASE STUDY| Cancer-killing bacteria Ralph, a...Ch. 19 - CASE STUDY| Cancer-killing bacteria Ralph, a...Ch. 19 - CASE STUDY |Cancer-killing bacteria Ralph, a...Ch. 19 - HOW DO WE KNOW? In this chapter, we focused on a...Ch. 19 - Prob. 2PDQCh. 19 - Why are most recombinant human proteins produced...Ch. 19 - Prob. 4PDQCh. 19 - One of the major causes of sickness, death, and...Ch. 19 - Prob. 6PDQCh. 19 - Sequencing the human genome and the development of...
Ch. 19 - Prob. 8PDQCh. 19 - As genetic testing becomes widespread, medical...Ch. 19 - What limits the use of differences in restriction...Ch. 19 - Might it make sense someday to sequence every...Ch. 19 - What is the main purpose of genome-wide...Ch. 19 - Prob. 13PDQCh. 19 - Prob. 14PDQCh. 19 -
15. In 2013 the actress Angelina Jolie elected to...Ch. 19 - Prob. 16PDQCh. 19 - Should the FDA regulate direct-to-consumer genetic...Ch. 19 - Prob. 18PDQCh. 19 - Prob. 19PDQCh. 19 - Private companies are now offering personal DNA...Ch. 19 - Yeager, M., et al.(Nature Genetics 39: 645–649,...Ch. 19 - In March 2010 Judge R. Sweet ruled to invalidate...
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- A 45-year-old woman undergoes genetic testing and discovers that she is at high risk for developing colon cancer and Alzheimer disease. Because her children have 50% of her genes, they may also be at an increased risk for these diseases. Does she have a moral or legal obligation to tell her children and other close relatives about the results of her genetic testing?arrow_forwardBy the time this book is published, it will likely be possible for you to obtain the sequence of your genome at nominal cost. Do you want this information? Explain the factors that affected your decision.arrow_forwardMr. I. M. Megabucks, the wealthiest man in the world, recently died. Since his death, three women have come forward. Each woman claims to have a child by Megabucks and demands a substantial share of his estate for her child. Lawyers for the estate have insisted on DNA typing of each of the alleged heirs. Fortunately, Megabucks anticipated trouble like this before he died, and he arranged to have a sample of his blood frozen for DNA typing. The results of the typing are shown in the figure below. Your job is to analyze the data and determine whether any of the children could be Megabucks' heir. Remember that every person has two of each chromosome, one inherited from his mother and one inherited from his father. Half of every person's DNA comes from his mother, and half comes from his father, so some of the DNA bands showing in the children will come from their mothers, and the rest will come from their fathers. The question is, could that father be Megabucks? For the first child,…arrow_forward
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- Listed below are 4 of the 13 genome sites used to create a standard DNA profile. Each site consists of a number of short tandem repeats: sets of 4 nucleotides repeated in a row within the genome. For each site, the number of repeats found at that site for this individual are listed: Imagine you perform a PCR procedure to create a DNA profile for this individual. Which of the following four gels correctly represents the DNA profile of this person?arrow_forwardDescribe, explain and elaborate down syndrome and genetic technologies are being utilized towards the said genetic disorder. It must include the following: (1) Good introduction; (2) Description or problem of Down Syndrome; (3) Genetic technology applied with the Down Syndrome; (4) Results or benefits; (5) Risks or issues involved; and (6) Conclusion with a good ending statement.arrow_forwardDNA dragnets have been so successful that some people have suggested that DNA samples of everyone should be stored at birth, so a profile could be made for anyone at any time. A. Do you think this is a good idea or not? And, B. do you think it useful or ethical for the FBI to store DNA samples from people who have been arrested but not yet convicted of a crime? Answer both questions,arrow_forward
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