A sixth-grade boy in California carried the mutation for CFTR (Cystic fibrosis Transmembrane conductance regulator) genes. He was transferred out of the middle school because school administrators thought that his mutation would pose a risk for the other students having cystic fibrosis at the school. After missing 11 days of school, a settlement has reached to the boy’s home to take him back to the school. Characters in the case: A boy in Palo Alto, California. Adequate information: A boy was having a mutation in the CFTR gene and the school administrators transferred him out of the middle school. They thought that the boy’s mutation for CFTR genes would pose a risk for other students at the school having the cystic fibrosis. By keeping in view to the Genetic Information Nondiscrimination Act, a settlement has reached to boy’s home for taking him back to the school. To determine: The ethical problems associated with this case and the concerns associated with the Genetic Information Non-discrimination Act (GINA).

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Answer 1

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Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 19, Problem 13PDQ

Summary Introduction

Case summary:

A sixth-grade boy in California carried the mutation for CFTR (Cystic fibrosis Transmembrane conductance regulator) genes. He was transferred out of the middle school because school administrators thought that his mutation would pose a risk for the other students having cystic fibrosis at the school. After missing 11 days of school, a settlement has reached to the boy’s home to take him back to the school.

Characters in the case:

A boy in Palo Alto, California.

Adequate information:

A boy was having a mutation in the CFTR gene and the school administrators transferred him out of the middle school. They thought that the boy’s mutation for CFTR genes would pose a risk for other students at the school having the cystic fibrosis. By keeping in view to the Genetic Information Nondiscrimination Act, a settlement has reached to boy’s home for taking him back to the school.

To determine:

The ethical problems associated with this case and the concerns associated with the Genetic Information Non-discrimination Act (GINA).

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A neutral mutation is, by definition, a mutation that does not result in the change of the encoded amino acid sequence of a gene. 1)True 2)False

You are working in the lab with two known carcinogens found in cigarette smoke: Benzo(a)pyren (BaP) and nitrosamine ketone (NNK). BaP is an aromatic hydrocarbon and the mechanism of carcinogenesis is through oxidation reactions with DNA. NNK is a nitrosoamine. Describe how these two kinds of carcinogens lead to mutations. (Be detailed. Remember you are graded on effort/completeness.)

Mutations in the HPRT1 gene in humans result in atleast two clinical syndromes. Consult OMIM (www.omim.org) by querying HPRT1; you will only needto look briefly at the top three hits (files #300322,300323, and 308000).a. What is the full name of the HPRT1 enzyme?b. On which chromosome is the HPRT1 gene located?c. Mutations in HPRT1 are associated with two different syndromes. What are these syndromes? Foreach, answer the following questions: (i) What arethe symptoms associated with the syndrome? (ii) Isthe mutant allele that causes the syndrome dominant, recessive, codominant, or incompletely dominant with respect to the normal allele, or do specialconditions apply? (iii) Is the syndrome associatedwith a loss-of-function or a gain-of-function disease allele? (iv) Does the syndrome display allelicheterogeneity? (v) Does the syndrome display locus heterogeneity? (Note: You do not need to understand everything in the OMIM entries to answerthese questions.)

Answer 2

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Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 19, Problem 13PDQ

Summary Introduction

Case summary:

A sixth-grade boy in California carried the mutation for CFTR (Cystic fibrosis Transmembrane conductance regulator) genes. He was transferred out of the middle school because school administrators thought that his mutation would pose a risk for the other students having cystic fibrosis at the school. After missing 11 days of school, a settlement has reached to the boy’s home to take him back to the school.

Characters in the case:

A boy in Palo Alto, California.

Adequate information:

A boy was having a mutation in the CFTR gene and the school administrators transferred him out of the middle school. They thought that the boy’s mutation for CFTR genes would pose a risk for other students at the school having the cystic fibrosis. By keeping in view to the Genetic Information Nondiscrimination Act, a settlement has reached to boy’s home for taking him back to the school.

To determine:

The ethical problems associated with this case and the concerns associated with the Genetic Information Non-discrimination Act (GINA).

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 19, Problem 13PDQ

Summary Introduction

Case summary:

A sixth-grade boy in California carried the mutation for CFTR (Cystic fibrosis Transmembrane conductance regulator) genes. He was transferred out of the middle school because school administrators thought that his mutation would pose a risk for the other students having cystic fibrosis at the school. After missing 11 days of school, a settlement has reached to the boy’s home to take him back to the school.

Characters in the case:

A boy in Palo Alto, California.

Adequate information:

A boy was having a mutation in the CFTR gene and the school administrators transferred him out of the middle school. They thought that the boy’s mutation for CFTR genes would pose a risk for other students at the school having the cystic fibrosis. By keeping in view to the Genetic Information Nondiscrimination Act, a settlement has reached to boy’s home for taking him back to the school.

To determine:

The ethical problems associated with this case and the concerns associated with the Genetic Information Non-discrimination Act (GINA).

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 19, Problem 13PDQ

Summary Introduction