Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 17, Problem 19PDQ
Summary Introduction
To determine: The ways in which ENCODE data help to verify the genes that have to be regulated by enhancers.
Introduction: Transcription is the process by which the information of the DNA strand is copied into a new molecule of messenger RNA. The DNA strand act as a template strand. The DNA store the genetic information in the nucleus of the cell.
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Where do enhancers bind? Are enhancers gene specific
How do activators bind enhancers in the first place if the enhancer DNA is covered with nucleosomes?
How do the ENCODE data vastly help determine which enhancers regulate which genes?
Chapter 17 Solutions
Concepts of Genetics (12th Edition)
Ch. 17 - Cancer cells often have abnormal patterns of...Ch. 17 - The hormone estrogen converts the estrogen...Ch. 17 - Each year in the United States, there are over...Ch. 17 - Prob. 2CSCh. 17 - Each year in the United States, there are over...Ch. 17 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 17 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 17 - What features of eukaryotes provide additional...Ch. 17 - Provide a definition of chromatin remodeling, and...Ch. 17 - Describe the organization of the interphase...
Ch. 17 - A number of experiments have demonstrated that...Ch. 17 - Provide a brief description of two different types...Ch. 17 - Present an overview of the manner in which...Ch. 17 - Prob. 9PDQCh. 17 - Explain how the addition of acetyl groups to...Ch. 17 - Distinguish between the cis-acting regulatory...Ch. 17 - Prob. 12PDQCh. 17 - Describe the manner in which activators and...Ch. 17 - Compare the control of gene regulation in...Ch. 17 - Many promoter regions contain CAAT boxes...Ch. 17 - Prob. 16PDQCh. 17 - Prob. 17PDQCh. 17 - Many transcriptional activators are proteins with...Ch. 17 - Prob. 19PDQCh. 17 - DNA supercoiling, which occurs when coiling...Ch. 17 - Prob. 21ESPCh. 17 - Prob. 22ESPCh. 17 - Because the degree of DNA methylation appears to...Ch. 17 - A particular type of anemia in humans, called...Ch. 17 - Regulation of the lac operon in E. coli (see...Ch. 17 - DNA methylation is commonly associated with a...Ch. 17 - During an examination of the genomic sequences...Ch. 17 - Prob. 28ESPCh. 17 - Although a single activator may bind many...Ch. 17 - Hereditary spherocytosis (HS) is a disorder...Ch. 17 - Transcription factors play key roles in the...
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- Explain in detail the role of super-enhancers. Give some examples. How the super-enhancers can be identified?arrow_forwardBriefly explain the steps to induce the expression of gene of interest using IPTG.arrow_forwardExplain one experimental strategy for determining the functional role of the mouse HoxD-3 gene.arrow_forward
- Identify the mechanisms of transcriptional,posttranscriptional, and translational control of geneexpression.arrow_forwardWhat is a CpG island? Where would you expect one to be located? How does the methylation of CpG islands affect gene expression?arrow_forwardDuring certain stages of development, the requirement forcertain gene products may require gene amplification. Whatpurpose does gene amplification serve?arrow_forward
- What do TATA boxes, initiators, and CpG islands have in common? Which was the first of these to be identified? Why?arrow_forwardIdentify three key ways that TrXG genes promote transcription with respect to: Mediator Complex Structurearrow_forwardWhy are regulatory mutations at the mouse Sonic hedgehog gene dominant and viable? Why do coding mutations cause more widespread defects?arrow_forward
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