Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 17, Problem 16PDQ
Summary Introduction

To determine: The differences between focused and dispersed promoters.

Introduction: The DNA contains a region called the promoter. The promoters are the special sequences that initiate the process of transcription. There are two types of promoters in eukaryotes. These are core promoters and proximal promoters. The core promoters have been further categorized into two types, namely focused promoters and dispersed promoters.

Summary Introduction

To determine: The genes that are associated with focused promoters and the genes that are associated with dispersed promoters.

Introduction: The essential parts of the promoters that start the process of transcription are known as core promoters. Focused promoters and dispersed promoters are the two types of core promoters. Focused promoters have only one start site, while dispersed promoters have multiple start sites.

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Explain what are dispersed core promoters ?
The following diagram show what is required for an active promoter of a gene of interest, where:A1 = Activator 1A2 = Activator 2Med = MediatorRep = Repressor   Based on the following data, predict: Chromatin conformation Methylation state of the proximal promoter If protein A1 is present or absent If protein A2 is present or absent If the mediator is present or absent If the repressor is absence or present If this gene is likely to be transcribed or notPlease note that this is an "all or nothing" bonus question, and no partial credit will be awarded. Selecting all answers will result in zero points awarded. Selecting at least one incorrect answer will result in zero points being awarded.    Question 28 options:   Euchromatin   Heterochromatin   Methylated promoter   Unmethylated promoter   Activator A1 present   Activator A1 absent   Activator A2 present…
You have isolated a protein that binds to DNA in the region upstream of the promoter sequence of a gene sys. If this protein is a positive regulator, which of the following would be true (multiple selection possible)? Loss-of-function mutations in the gene encoding the DNA-binding protein would cause constitutive expression of sys. Loss-of-function mutations in the gene encoding the DNA-binding protein would result in little or no expression of sys.

Chapter 17 Solutions

Concepts of Genetics (12th Edition)

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