Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 16, Problem 34P
Interpretation Introduction

Interpretation:

The energetic barriers that prevent glycolysis to occur in reverse and the energy required to overcome this barrier needs to be determined.

Concept introduction:

Glycolysis is the process that occurs in the cytoplasm of the cell. It is the breakdown of one molecule of glucose into two molecules of pyruvic acid. During this process energy is released in the form of two moles of ATP. The purpose of glycolysis is to maintain the blood glucose level.

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They are everywhere. What energetic barrier prevents glycolysis from simply running in reverse tosynthesis glucose? What is the energetic cost to overcome this barrier?
This is the ATP accounting question. You are limited to the carbon in the following molecules:   One xylulose 5-phosphate, One glyceraldehyde 3-phosphate, One sedoheptulose 7-phosphate, 1 Oxaloacetate, and 3 carbon dioxide   A) Disregard regulation completely regarding pathway activity, using only the enzymes of glycolysis, pentose phosphate pathway, and citric acid cycle, what is the maximum ATP one can generate with these molecules?          B) Disregard regulation completely regarding pathway activity, using only the enzymes of glycolysis, Calvin-               Benson-Bassham cycle, and citric acid cycle, what is the maximum ATP one can generate with these                     molecules (in this instance only, you also are given 3 ATP and note that you do NOT need to regenerate                   substrates for rubisco once you get through this enzyme).
I'm confused about glycolysis and gluconeogenesis. Question: What is the function of glyceraldehyde 3-phosphate dehydrogenase? Is it because of  -> The incorporation of a phosphate from ATP and reduction of glyceraldehyde 3-phosphate or ->The incorporation of phosphate from inorganic phosphate and reduction of glyceraldehyde 3-phosphate. or -> The incorporation of phosphate from inorganic phosphate and oxidation of glyceraldehyde 3-phosphate
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