Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 15, Problem 19PDQ
Distinguish between the cis-acting regulatory elements referred to as promoters and enhancers.
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Describe how a regulatory transcription factor binds to a regulatory element.
Describe three ways that the function of a regulatory transcription factor can be modulated.
Regulation can occur at many steps in the pathway of gene expression. Briefly describe at least one example of a regulator at the level of:
a) transcriptional initiation
b) protein stability
c) posttranslational protein modification
Chapter 15 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 15 -
CASE STUDY | A mysterious muscular dystrophy
A...Ch. 15 -
CASE STUDY |A mysterious muscular dystrophy
A...Ch. 15 -
CASE STUDY |A mysterious muscular dystrophy
A...Ch. 15 -
HOW DO WE KNOW?
1. In this chapter, we have...Ch. 15 -
2. Review the Chapter Concepts list on p. 280....Ch. 15 - Describe which enzymes are required for lactose...Ch. 15 - Contrast positive versus negative regulation of...Ch. 15 -
5. Both attenuation and riboswitches rely on...Ch. 15 - For the lac genotypes shown in the accompanying...Ch. 15 -
7. For the genotypes and conditions (lactose...
Ch. 15 -
8. The locations of numerous lacI– and lacIs...Ch. 15 - Explain why catabolite repression is used in...Ch. 15 - Describe experiments that would confirm whether or...Ch. 15 - Predict the level of genetic activity of the lac...Ch. 15 - Predict the effect on the inducibility of the lac...Ch. 15 -
13. Describe the role of attenuation in the...Ch. 15 -
14. In a theoretical operon, genes A, B, C, and D...Ch. 15 - A bacterial operon is responsible for production...Ch. 15 - A marine bacterium is isolated and is shown to...Ch. 15 -
17. Why is gene regulation more complex in a...Ch. 15 -
18. List and define the levels of eukaryotic gene...Ch. 15 -
19. Distinguish between the cis-acting regulatory...Ch. 15 - Prob. 20PDQCh. 15 - Compare the control of gene regulation in...Ch. 15 - Many eukaryotic promoter regions contain CAAT...Ch. 15 -
23. What is RNA-induced gene silencing in...Ch. 15 - Although it is customary to consider...Ch. 15 - DNA methylation is commonly associated with a...Ch. 15 - The interphase nucleus appears to be a highly...Ch. 15 - It has been estimated that at least two-thirds of...
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- Explain how the expression of a single gene can be quickly,efficiently,and specifically shut down at the transcriptional,posttranscriptional,and posttranslational stages through thecoordinated expression of a transcriptional repressor, an miRNA,and a ubiquitin ligase.arrow_forwarddescribe the 4 types of suppressors inducer, repressor, promoter, and operator.arrow_forwardEnhancers contain binding sites for transcription factors that regulate transcription. are activators that act across insulator barriers. contain binding sites for the basal transcription apparatus. are necessary for transcription, but are not involved in regulating transcription.arrow_forward
- Briefly describe the significance of regulatory factors in transcription process. Why the promoter is called an essential regulatory element.arrow_forwardExplain Molecular Mechanisms of Transcription Repression and Activation.arrow_forwardPromoters and Enhancers Are the Major cis-Acting Regulatory Elementsarrow_forward
- Regarding transcriptional promoter sites, which of the following statements are true? Select one or more than one: a)They are located in the gene (DNA) whose information will be transcribed b)They are found at the 3 'end of the gene that will be transcribed c)Some of them are called 'TATA box' d)They are found in the DNA, 'upstream' of the gene to be transcribed. e)They are proteins of the cytoplasmarrow_forwardUsing three examples, describe how allosteric sites are important in the function of genetic regulatory proteins.arrow_forwardDefine how Activators and Repressors Interact with General TranscriptionFactors ?arrow_forward
- What are general transcription factors? When do you expect to find them? What is a cis acting regulatory sequence? Where are they located in comparison with the gene they are regulating?arrow_forwardDescribe three types of post-transcriptional regulation of protein coding genes.arrow_forwardIdentify the mechanisms of transcriptional,posttranscriptional and translation control of gene expressionarrow_forward
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