Life: The Science of Biology
Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 14.6, Problem 2R
Summary Introduction

To review:

The presence of ‘code’ that can help in determination of posttranslational modifications such as phosphorylation or glycosylation. Also, to decipher if they are related to the genetic code.

Introduction:

The modifications that occur in the protein after it has been translated from the ribosomes are called post translational modifications. They can be of various types and are responsible for the active form of protein.

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ADP ribosylation is one example of post-translational modification of an enzyme. Which statements about the process is true? ADP ribosylation will affect protein folding because of the addition of a large molecule ADP ribose can be added to the amine group of lysine or glutamine The ending of DNA around histones in the nucleus is altered by the ADP -ribosylation of the histone proteins in cancer cells  ADP ribosylation requires ADP and the target protein as the substrates in the ADP ribosylation ADP ribosylation of phosphoinositol is an important step in signaling through a G protein-coupled receptor pathway.
Which of these is a post-translational modification that targets a protein to the proteasome? O Ubiquitination O SUMOylation O Phosphorylation O Glycosylation O Methylation
To create a functional hormone, insulin pre-mRNA is first made during the process of transcription in the nucleus. It is then modified and exported out of the nucleus. Next, a BLANK (a specific molecule in the cell) carries-out translation using tRNAs to translate the sequence into amino acids. The polypeptide is further processed and then secreted from the cell.
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