Foundations in Microbiology
10th Edition
ISBN: 9781259705212
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12.L1, Problem 2MCQ
Which statement is not an aim in the use of drugs for antimicrobial chemotherapy? The drug should
a. have selective toxicity
b. be active even in high dilutions
c. be broken down and excreted rapidly
d. be microbicidal
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Chapter 12 Solutions
Foundations in Microbiology
Ch. 12.1 - State the goals of antimicrobial therapy.Ch. 12.1 - Discuss the origins of antimicrobial drugs.Ch. 12.1 - Differentiate between antibiotics, synthetic...Ch. 12.1 - Describe some of the special strategies of...Ch. 12.1 - Explain what is meant by a drug's spectrum and how...Ch. 12.1 - Summarize the five modes of action of...Ch. 12.1 - Differentiate between antibiotics and synthetic...Ch. 12.1 - Differentiate between narrow-spectrum and...Ch. 12.1 - Can you determine why some drugs have narrower...Ch. 12.1 - What is the major source of antibiotics and what...
Ch. 12.1 - Prob. 5CYPCh. 12.1 - Prob. 6CYPCh. 12.1 - Explain the major modes of action of antimicrobial...Ch. 12.1 - Explain the concept of competitive inhibition, and...Ch. 12.1 - What would be the extended effects of drugs that...Ch. 12.2 - Describe the classes of antibacterial drugs that...Ch. 12.2 - Prob. 8ELOCh. 12.2 - Indicate which types of antibacterial drugs block...Ch. 12.2 - Describe some new classes of antibacterial drugs...Ch. 12.2 - Construet a chart that summarizes the modes of...Ch. 12.2 - Why do the penicillin and cephalosporin groups of...Ch. 12.3 - Categorize antimicrobial drugs that are effective...Ch. 12.3 - Prob. 12ELOCh. 12.3 - Prob. 13ELOCh. 12.3 - Prob. 14ELOCh. 12.3 - Prob. 12CYPCh. 12.3 - Explain why there are fewer antifungal,...Ch. 12.3 - Prob. 14CYPCh. 12.3 - Summarize the origins and biological actions of...Ch. 12.4 - Describe the development of microbial drug...Ch. 12.4 - Explain the major mechanisms by which microbes...Ch. 12.4 - Review some of the ways to reduce levels of drug...Ch. 12.4 - Discuss how drug resistance spreads through a...Ch. 12.4 - Prob. 16CYPCh. 12.4 - Prob. 17CYPCh. 12.4 - Outline several situations or events that increase...Ch. 12.4 - Prob. 19CYPCh. 12.5 - Summarize the adverse effects of drugs on the...Ch. 12.5 - Describe some of the toxic effects of drugs on...Ch. 12.5 - Prob. 21ELOCh. 12.5 - Explain the ways in which drugs alter the normal...Ch. 12.5 - Prob. 20CYPCh. 12.5 - Prob. 21CYPCh. 12.5 - Prob. 22CYPCh. 12.5 - Prob. 23CYPCh. 12.6 - Prob. 23ELOCh. 12.6 - Describe the principles behind sensitivity testing...Ch. 12.6 - Explain the uses of the minimum inhibitory...Ch. 12.6 - Prob. 26ELOCh. 12.6 - Prob. 27ELOCh. 12.6 - Prob. 24CYPCh. 12.6 - Briefly describe the Kirby-Bauer test and its...Ch. 12.6 - Prob. 26CYPCh. 12.6 - Prob. 27CYPCh. 12.6 - Discuss the general factors to consider in...Ch. 12.L1 - A compound synthesized by bacteria or fungi that...Ch. 12.L1 - Which statement is not an aim in the use of drugs...Ch. 12.L1 - Microbial resistance to drugs is acquired through...Ch. 12.L1 - R factors are ________ that contain a code for...Ch. 12.L1 - When a patient's immune system becomes reactive to...Ch. 12.L1 - An antibiotic that disrupts the normal flora can...Ch. 12.L1 - Prob. 7MCQCh. 12.L1 - Prob. 8MCQCh. 12.L1 - Prob. 9MCQCh. 12.L1 - Which of the following modes of action would be...Ch. 12.L1 - The MIC is the of a drug thal is required to...Ch. 12.L1 - An antimicrobial drug with a ________ therapeutic...Ch. 12.L1 - Matching. Select the mode of action for each drug...Ch. 12.L1 - What was the purpose of giving postexposure...Ch. 12.L1 - What is a probable reason that tuberculosis...Ch. 12.L1 - Summarize the major problems with drug therapy as...Ch. 12.L1 - Using the diagram as a guide, briefly explain how...Ch. 12.L1 - Observe table 12.4 with regard to type of microbe...Ch. 12.L1 - Drugs are often given to patients before going...Ch. 12.L1 - Write an essay covering some of the main concerns...Ch. 12.L1 - Prob. 5WCCh. 12.L1 - Explain the kinds of tests that would...Ch. 12.L1 - Summarize the primary reasons that we find...Ch. 12.L2 - In 2015 the WHO surveyed 10,000 people on the...Ch. 12.L2 - Explain a simple test one could do to determine if...Ch. 12.L2 - Prob. 3CTCh. 12.L2 - You have been directed to take a sample from a...Ch. 12.L2 - From the results shown in figure 12.21, determine...Ch. 12.L2 - Explain why drugs that interfere with the...Ch. 12.L2 - In cases in which it is not possible to culture or...Ch. 12.L2 - Reviewing drug characteristics, choose an...Ch. 12.L2 - a. Using table 12.10 as a reference, find and...Ch. 12.L2 - For the following figures a-e, research the...
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- Which of the following statements concerning drug delivery system is INCORRECT?* A.Drugs with good aqueous solubility are good for controlled release formulation. B.The delay-released form is also called extended release form. C.Absorption rate is higher in compressed tablets than that in capsules. D.Drug core with polymer membrane coating belongs to diffusion sustained system. E.Disintegration and dissolution can occur at the same time.arrow_forwardAn antimicrobial drug with a therapeutic index is a betterchoice than one with a therapeutic index.a. low, high b. high, lowarrow_forwardMatch the following drug targets with the type of antibiotic that uses them (answers may be used more than once or not at all). a. Cell wall b.Cell membrane c. Protein synthesis (Transcription/Translation) d. Metabolic Pathway e. Nucleic Acid synthesis Chloramphenicol Clindamycin Erythromycin Doxycycline Sulfonamides Answer these multiple-choice questions as well. Please give just the answer and no explanation. 1. Which is not true of virus capsids?a. They surround and protect viral nucleic acidb. Always icosahedral in shapec. Remain outside of host bacterial cells while the nucleic acid is injected into the bacterial celld. Enters host animal cells together with the nucleic acid e. Made up of protein subunits called capsomeres 2. All viruses have: a. DNA b. RNAc. Envelopesd. Glycoprotein spikes e. Host specificity 3. Use the following to select the sequence of events during replication of DNA viruses in animal cells:1 = replication of viral nucleic acid2 = adsorption3…arrow_forward
- A compound synthesized by bacteria or fungi that destroys or inhibitsthe growth of other microbes is a(n)a. synthetic drug b. antibiotic c. antimicrobial drug d. competitive inhibitorarrow_forwardTechnically speaking, true antibiotics are drugs… A. Produced naturally by microbes B. Taken orally, not injected. C. Used to treat any microbial infection D. Used to treat any bacterial disease.arrow_forwardWhich of the following situations related to oral chemotherapy treatment is most likely to result in serious adverse effects? A. A patient obtains a refill of the prescription and continues to take the medication during the "off week". B. A family member brings the medication bottle and dosing schedule to the follow-up appointment. C. A patient misses a follow-up appointment because he is unable to pay for transportation to the clinic. D. The new cycle of treatment is delayed because the edication is unavailable from the pharmacy.arrow_forward
- Which of the following is not a factor that should be considered when selecting a antimicrobial drug? A. The nature of the microbe causing the infection B. The overall medical condition of the patient C. The origin of the drug D. The degree of susceptibility of the microbe to that drugarrow_forwardPlease choose all the ADVANTAGES of protein-based drugs such as antibodies compare to small molecules from the following options. A. high selectivity B. Biocompatibility C. stable to metabolism D. oral bioavailability E. long half-life F. high activityarrow_forwardIndicate whether each statement is true or false, and justify your answer.Phase III clinical trials are a minor part of the drug development process in the US.arrow_forward
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