Foundations in Microbiology
10th Edition
ISBN: 9781259705212
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12.3, Problem 15CYP
Summarize the origins and biological actions of interferon-based drugs.
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As a research scientist working on MS detail the possible strategic directions you could take to produce and purify large quantities of the human interferon β-1b. choose which strategy you think the team should take and why.
Scenario: You ae a nurse in an inpatient acute care rehabilitation center. Your client is a 55-year-old woman who has been diagnosed with MS. She is determined to learn a much as she can about the treatments available for her disease. The client’s questions are presented below. Your clients asks: “My provider prescribed interferon beta.
” clients asks: “What kind of side effects can I expect from the interferon beta?” Which teaching statement by the nurse is correct SELECT ALL THAT APPLY)bA. Flulike reactions occur oftenB. Interferon beta can cause influenzaC. Interferon beta can suppress bone marrow functionD. Interferon beta can injure the liverE. Interferon beta will put the client at risk for infection
What is the strategy in drug design to fight AIDS?
Chapter 12 Solutions
Foundations in Microbiology
Ch. 12.1 - State the goals of antimicrobial therapy.Ch. 12.1 - Discuss the origins of antimicrobial drugs.Ch. 12.1 - Differentiate between antibiotics, synthetic...Ch. 12.1 - Describe some of the special strategies of...Ch. 12.1 - Explain what is meant by a drug's spectrum and how...Ch. 12.1 - Summarize the five modes of action of...Ch. 12.1 - Differentiate between antibiotics and synthetic...Ch. 12.1 - Differentiate between narrow-spectrum and...Ch. 12.1 - Can you determine why some drugs have narrower...Ch. 12.1 - What is the major source of antibiotics and what...
Ch. 12.1 - Prob. 5CYPCh. 12.1 - Prob. 6CYPCh. 12.1 - Explain the major modes of action of antimicrobial...Ch. 12.1 - Explain the concept of competitive inhibition, and...Ch. 12.1 - What would be the extended effects of drugs that...Ch. 12.2 - Describe the classes of antibacterial drugs that...Ch. 12.2 - Prob. 8ELOCh. 12.2 - Indicate which types of antibacterial drugs block...Ch. 12.2 - Describe some new classes of antibacterial drugs...Ch. 12.2 - Construet a chart that summarizes the modes of...Ch. 12.2 - Why do the penicillin and cephalosporin groups of...Ch. 12.3 - Categorize antimicrobial drugs that are effective...Ch. 12.3 - Prob. 12ELOCh. 12.3 - Prob. 13ELOCh. 12.3 - Prob. 14ELOCh. 12.3 - Prob. 12CYPCh. 12.3 - Explain why there are fewer antifungal,...Ch. 12.3 - Prob. 14CYPCh. 12.3 - Summarize the origins and biological actions of...Ch. 12.4 - Describe the development of microbial drug...Ch. 12.4 - Explain the major mechanisms by which microbes...Ch. 12.4 - Review some of the ways to reduce levels of drug...Ch. 12.4 - Discuss how drug resistance spreads through a...Ch. 12.4 - Prob. 16CYPCh. 12.4 - Prob. 17CYPCh. 12.4 - Outline several situations or events that increase...Ch. 12.4 - Prob. 19CYPCh. 12.5 - Summarize the adverse effects of drugs on the...Ch. 12.5 - Describe some of the toxic effects of drugs on...Ch. 12.5 - Prob. 21ELOCh. 12.5 - Explain the ways in which drugs alter the normal...Ch. 12.5 - Prob. 20CYPCh. 12.5 - Prob. 21CYPCh. 12.5 - Prob. 22CYPCh. 12.5 - Prob. 23CYPCh. 12.6 - Prob. 23ELOCh. 12.6 - Describe the principles behind sensitivity testing...Ch. 12.6 - Explain the uses of the minimum inhibitory...Ch. 12.6 - Prob. 26ELOCh. 12.6 - Prob. 27ELOCh. 12.6 - Prob. 24CYPCh. 12.6 - Briefly describe the Kirby-Bauer test and its...Ch. 12.6 - Prob. 26CYPCh. 12.6 - Prob. 27CYPCh. 12.6 - Discuss the general factors to consider in...Ch. 12.L1 - A compound synthesized by bacteria or fungi that...Ch. 12.L1 - Which statement is not an aim in the use of drugs...Ch. 12.L1 - Microbial resistance to drugs is acquired through...Ch. 12.L1 - R factors are ________ that contain a code for...Ch. 12.L1 - When a patient's immune system becomes reactive to...Ch. 12.L1 - An antibiotic that disrupts the normal flora can...Ch. 12.L1 - Prob. 7MCQCh. 12.L1 - Prob. 8MCQCh. 12.L1 - Prob. 9MCQCh. 12.L1 - Which of the following modes of action would be...Ch. 12.L1 - The MIC is the of a drug thal is required to...Ch. 12.L1 - An antimicrobial drug with a ________ therapeutic...Ch. 12.L1 - Matching. Select the mode of action for each drug...Ch. 12.L1 - What was the purpose of giving postexposure...Ch. 12.L1 - What is a probable reason that tuberculosis...Ch. 12.L1 - Summarize the major problems with drug therapy as...Ch. 12.L1 - Using the diagram as a guide, briefly explain how...Ch. 12.L1 - Observe table 12.4 with regard to type of microbe...Ch. 12.L1 - Drugs are often given to patients before going...Ch. 12.L1 - Write an essay covering some of the main concerns...Ch. 12.L1 - Prob. 5WCCh. 12.L1 - Explain the kinds of tests that would...Ch. 12.L1 - Summarize the primary reasons that we find...Ch. 12.L2 - In 2015 the WHO surveyed 10,000 people on the...Ch. 12.L2 - Explain a simple test one could do to determine if...Ch. 12.L2 - Prob. 3CTCh. 12.L2 - You have been directed to take a sample from a...Ch. 12.L2 - From the results shown in figure 12.21, determine...Ch. 12.L2 - Explain why drugs that interfere with the...Ch. 12.L2 - In cases in which it is not possible to culture or...Ch. 12.L2 - Reviewing drug characteristics, choose an...Ch. 12.L2 - a. Using table 12.10 as a reference, find and...Ch. 12.L2 - For the following figures a-e, research the...
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- All of the following are not true about immune modulators, except: Infection control is an integral part of drug therapy. Most can be safely recommended in children. Interferons and interleukins have many drug-to-drug interactions. None of the abovearrow_forwardDescribe the mechanism by which interferon acts as an antiviralcompound.arrow_forwardScenario: You ae a nurse in an inpatient acute care rehabilitation center. Your client is a 55-year-old woman who has been diagnosed with MS. She is determined to learn a much as she can about the treatments available for her disease. The client’s questions are presented below. Your clients asks: “My provider prescribed interferon beta. Which statement by the nurse should be included in teaching? PLEASE CHECK THE ANSWERS AND RESEARCH.A. Interferon beta is a naturally occurring glycoprotein within the body/INTERFERON BETA IS A NATURALLY OCCURING HORMONE WITHIN THE BODY THAT INCREASES RECEPTOR RESPONSE. B. Interferon beta inhibits can decrease the frequency and severity of attacksC. Interferon beta suppressed T-helper cell activity in the immune systemD. Interferon beta prevents infections by strengthening the immune system-arrow_forward
- Explain the multifaceted role of interferons as first responders to viral infection: Identify important target ISGs. Discuss the general mechanisms by which interferon induced genes block virus replication.arrow_forwardDiscuss the differences between conventional T cell therapy and Chimeric Antigen Receptor (CAR) T cells.arrow_forward"Selective NSAIDs can reduce inflammation and pain". Briefly explain this statement. Use your own words to explainarrow_forward
- All of the following are not true about immune modulators, except: Infection control is an integral part of drug therapy. Most can be safely recommended in children. Interferons and interleukins have many drug-to-drug interactions. None of the above (i am torn between Interferons and interleukins have many drug-to-drug interactionsa and none of the above)arrow_forwardDefine species resistance.arrow_forwardDiscuss the role of immunosuppressive therapy in organ transplantation and in the treatment of autoimmune diseases.arrow_forward
- Statement: In Yescarta treatment, the patient receives modified T-cells from a family member. Is this statement true or false?arrow_forwardExplain the multifaceted role of interferons as first responders to viral infection: What types of interferons are activated by viruses at the earliest stages of infection? How are interferons activated? What types of stimuli activate interferons at the earliest stages of viral infection.? Identify the receptors to which interferon binds and how their activation affects gene expression?arrow_forwardDefine monoclonal antibodies and list some specificapplications of this technology.arrow_forward
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