Foundations in Microbiology
10th Edition
ISBN: 9781259705212
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12.L1, Problem 10MCQ
Which of the following modes of action would be most selectively toxic?
a. interrupting ribosomal function
b. dissolving the cell membrane
c. preventing cell wall synthesis
d. inhibiting
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Match the following drug targets with the type of antibiotic that uses them (answers may be used more than once or not at all).
a. Cell wall
b.Cell membrane
c. Protein synthesis (Transcription/Translation)
d. Metabolic Pathway
e. Nucleic Acid synthesis
Chloramphenicol
Clindamycin
Erythromycin
Doxycycline
Sulfonamides
Answer these multiple-choice questions as well. Please give just the answer and no explanation.
1. Which is not true of virus capsids?a. They surround and protect viral nucleic acidb. Always icosahedral in shapec. Remain outside of host bacterial cells while the nucleic acid is injected into the bacterial
celld. Enters host animal cells together with the nucleic acid
e. Made up of protein subunits called capsomeres
2. All viruses have:
a. DNA
b. RNAc. Envelopesd. Glycoprotein spikes
e. Host specificity
3. Use the following to select the sequence of events during replication of DNA viruses in animal
cells:1 = replication of viral nucleic acid2 = adsorption3…
Which of the following compounds represents a peptidoglycan specific antibiotic ?
A. tetracycline
B. chloramphenicol
C. penicillin
D. aspirin
Which of the following is not used as an antiseptic?
A. Chlorhexidine
B. Phenol
C. Iodophor
D. Hydrogen Peroxide
Chapter 12 Solutions
Foundations in Microbiology
Ch. 12.1 - State the goals of antimicrobial therapy.Ch. 12.1 - Discuss the origins of antimicrobial drugs.Ch. 12.1 - Differentiate between antibiotics, synthetic...Ch. 12.1 - Describe some of the special strategies of...Ch. 12.1 - Explain what is meant by a drug's spectrum and how...Ch. 12.1 - Summarize the five modes of action of...Ch. 12.1 - Differentiate between antibiotics and synthetic...Ch. 12.1 - Differentiate between narrow-spectrum and...Ch. 12.1 - Can you determine why some drugs have narrower...Ch. 12.1 - What is the major source of antibiotics and what...
Ch. 12.1 - Prob. 5CYPCh. 12.1 - Prob. 6CYPCh. 12.1 - Explain the major modes of action of antimicrobial...Ch. 12.1 - Explain the concept of competitive inhibition, and...Ch. 12.1 - What would be the extended effects of drugs that...Ch. 12.2 - Describe the classes of antibacterial drugs that...Ch. 12.2 - Prob. 8ELOCh. 12.2 - Indicate which types of antibacterial drugs block...Ch. 12.2 - Describe some new classes of antibacterial drugs...Ch. 12.2 - Construet a chart that summarizes the modes of...Ch. 12.2 - Why do the penicillin and cephalosporin groups of...Ch. 12.3 - Categorize antimicrobial drugs that are effective...Ch. 12.3 - Prob. 12ELOCh. 12.3 - Prob. 13ELOCh. 12.3 - Prob. 14ELOCh. 12.3 - Prob. 12CYPCh. 12.3 - Explain why there are fewer antifungal,...Ch. 12.3 - Prob. 14CYPCh. 12.3 - Summarize the origins and biological actions of...Ch. 12.4 - Describe the development of microbial drug...Ch. 12.4 - Explain the major mechanisms by which microbes...Ch. 12.4 - Review some of the ways to reduce levels of drug...Ch. 12.4 - Discuss how drug resistance spreads through a...Ch. 12.4 - Prob. 16CYPCh. 12.4 - Prob. 17CYPCh. 12.4 - Outline several situations or events that increase...Ch. 12.4 - Prob. 19CYPCh. 12.5 - Summarize the adverse effects of drugs on the...Ch. 12.5 - Describe some of the toxic effects of drugs on...Ch. 12.5 - Prob. 21ELOCh. 12.5 - Explain the ways in which drugs alter the normal...Ch. 12.5 - Prob. 20CYPCh. 12.5 - Prob. 21CYPCh. 12.5 - Prob. 22CYPCh. 12.5 - Prob. 23CYPCh. 12.6 - Prob. 23ELOCh. 12.6 - Describe the principles behind sensitivity testing...Ch. 12.6 - Explain the uses of the minimum inhibitory...Ch. 12.6 - Prob. 26ELOCh. 12.6 - Prob. 27ELOCh. 12.6 - Prob. 24CYPCh. 12.6 - Briefly describe the Kirby-Bauer test and its...Ch. 12.6 - Prob. 26CYPCh. 12.6 - Prob. 27CYPCh. 12.6 - Discuss the general factors to consider in...Ch. 12.L1 - A compound synthesized by bacteria or fungi that...Ch. 12.L1 - Which statement is not an aim in the use of drugs...Ch. 12.L1 - Microbial resistance to drugs is acquired through...Ch. 12.L1 - R factors are ________ that contain a code for...Ch. 12.L1 - When a patient's immune system becomes reactive to...Ch. 12.L1 - An antibiotic that disrupts the normal flora can...Ch. 12.L1 - Prob. 7MCQCh. 12.L1 - Prob. 8MCQCh. 12.L1 - Prob. 9MCQCh. 12.L1 - Which of the following modes of action would be...Ch. 12.L1 - The MIC is the of a drug thal is required to...Ch. 12.L1 - An antimicrobial drug with a ________ therapeutic...Ch. 12.L1 - Matching. Select the mode of action for each drug...Ch. 12.L1 - What was the purpose of giving postexposure...Ch. 12.L1 - What is a probable reason that tuberculosis...Ch. 12.L1 - Summarize the major problems with drug therapy as...Ch. 12.L1 - Using the diagram as a guide, briefly explain how...Ch. 12.L1 - Observe table 12.4 with regard to type of microbe...Ch. 12.L1 - Drugs are often given to patients before going...Ch. 12.L1 - Write an essay covering some of the main concerns...Ch. 12.L1 - Prob. 5WCCh. 12.L1 - Explain the kinds of tests that would...Ch. 12.L1 - Summarize the primary reasons that we find...Ch. 12.L2 - In 2015 the WHO surveyed 10,000 people on the...Ch. 12.L2 - Explain a simple test one could do to determine if...Ch. 12.L2 - Prob. 3CTCh. 12.L2 - You have been directed to take a sample from a...Ch. 12.L2 - From the results shown in figure 12.21, determine...Ch. 12.L2 - Explain why drugs that interfere with the...Ch. 12.L2 - In cases in which it is not possible to culture or...Ch. 12.L2 - Reviewing drug characteristics, choose an...Ch. 12.L2 - a. Using table 12.10 as a reference, find and...Ch. 12.L2 - For the following figures a-e, research the...
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- Define the following terms: a. turnover b. cyt P450 c. detoxication d. detoxification e. epoxidearrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardWhich of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic indexarrow_forward
- Select all of the pathways that can lead to pore production in a microbial cell. A. Alternative B. Lectin C. Classicalarrow_forwardA compound synthesized by bacteria or fungi that destroys or inhibitsthe growth of other microbes is a(n)a. synthetic drug b. antibiotic c. antimicrobial drug d. competitive inhibitorarrow_forwardAn antiviral drug that is a guianine analog would have an antiviral mode of action that: a) blocks penetration b) blocks DNA replication c) inhibits peptidoglycan cross linking d) blocks maturation e) bonds to ergosterol in the cell membranearrow_forward
- Which ONE of the following best describes ciprofloxacin? Select one: A. Active against Streptococcus pneumoniae B. An inhibitor of RNA synthesis C. An antimicrobial prodrug D. A natural product produced by Streptomyces spp. E. Subject to new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effectsarrow_forwardAn example of an agent that has lowers the surface tension of cells isarrow_forwarda) Biofilm is: a. a complex established community of microorganisms on solid surfaces b. is a layer of millions of identical bacteria on solid surfaces c. is a layer of compounds released from the tissue as a protection against pathogenic microorganisms d. All of these are correct b) Capsule formation is associated with the virulence of pathogenic bacteria. Why? Select all that apply. a. They are sticky and attach better b. They can escape phagocytosis c. The capsule makes them grow/multiply faster d. They kill immune cellsarrow_forward
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