Foundations in Microbiology
10th Edition
ISBN: 9781259705212
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12.1, Problem 3CYP
Can you determine why some drugs have narrower spectra than others? (Hint: Look at their mode of action.)
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Can you determine why some drugs have narrower spectra thanothers? (Hint: Look at their mode of action.)
What is an example of two drugs that produce a synergistic (also known as
hyperadditive) effect? What is the concern about drugs that have synergistic effects?
Note: you can describe the classes of drugs rather than using specific drug names.
Can you determine why some drugs have narrower spectra than others?
Chapter 12 Solutions
Foundations in Microbiology
Ch. 12.1 - State the goals of antimicrobial therapy.Ch. 12.1 - Discuss the origins of antimicrobial drugs.Ch. 12.1 - Differentiate between antibiotics, synthetic...Ch. 12.1 - Describe some of the special strategies of...Ch. 12.1 - Explain what is meant by a drug's spectrum and how...Ch. 12.1 - Summarize the five modes of action of...Ch. 12.1 - Differentiate between antibiotics and synthetic...Ch. 12.1 - Differentiate between narrow-spectrum and...Ch. 12.1 - Can you determine why some drugs have narrower...Ch. 12.1 - What is the major source of antibiotics and what...
Ch. 12.1 - Prob. 5CYPCh. 12.1 - Prob. 6CYPCh. 12.1 - Explain the major modes of action of antimicrobial...Ch. 12.1 - Explain the concept of competitive inhibition, and...Ch. 12.1 - What would be the extended effects of drugs that...Ch. 12.2 - Describe the classes of antibacterial drugs that...Ch. 12.2 - Prob. 8ELOCh. 12.2 - Indicate which types of antibacterial drugs block...Ch. 12.2 - Describe some new classes of antibacterial drugs...Ch. 12.2 - Construet a chart that summarizes the modes of...Ch. 12.2 - Why do the penicillin and cephalosporin groups of...Ch. 12.3 - Categorize antimicrobial drugs that are effective...Ch. 12.3 - Prob. 12ELOCh. 12.3 - Prob. 13ELOCh. 12.3 - Prob. 14ELOCh. 12.3 - Prob. 12CYPCh. 12.3 - Explain why there are fewer antifungal,...Ch. 12.3 - Prob. 14CYPCh. 12.3 - Summarize the origins and biological actions of...Ch. 12.4 - Describe the development of microbial drug...Ch. 12.4 - Explain the major mechanisms by which microbes...Ch. 12.4 - Review some of the ways to reduce levels of drug...Ch. 12.4 - Discuss how drug resistance spreads through a...Ch. 12.4 - Prob. 16CYPCh. 12.4 - Prob. 17CYPCh. 12.4 - Outline several situations or events that increase...Ch. 12.4 - Prob. 19CYPCh. 12.5 - Summarize the adverse effects of drugs on the...Ch. 12.5 - Describe some of the toxic effects of drugs on...Ch. 12.5 - Prob. 21ELOCh. 12.5 - Explain the ways in which drugs alter the normal...Ch. 12.5 - Prob. 20CYPCh. 12.5 - Prob. 21CYPCh. 12.5 - Prob. 22CYPCh. 12.5 - Prob. 23CYPCh. 12.6 - Prob. 23ELOCh. 12.6 - Describe the principles behind sensitivity testing...Ch. 12.6 - Explain the uses of the minimum inhibitory...Ch. 12.6 - Prob. 26ELOCh. 12.6 - Prob. 27ELOCh. 12.6 - Prob. 24CYPCh. 12.6 - Briefly describe the Kirby-Bauer test and its...Ch. 12.6 - Prob. 26CYPCh. 12.6 - Prob. 27CYPCh. 12.6 - Discuss the general factors to consider in...Ch. 12.L1 - A compound synthesized by bacteria or fungi that...Ch. 12.L1 - Which statement is not an aim in the use of drugs...Ch. 12.L1 - Microbial resistance to drugs is acquired through...Ch. 12.L1 - R factors are ________ that contain a code for...Ch. 12.L1 - When a patient's immune system becomes reactive to...Ch. 12.L1 - An antibiotic that disrupts the normal flora can...Ch. 12.L1 - Prob. 7MCQCh. 12.L1 - Prob. 8MCQCh. 12.L1 - Prob. 9MCQCh. 12.L1 - Which of the following modes of action would be...Ch. 12.L1 - The MIC is the of a drug thal is required to...Ch. 12.L1 - An antimicrobial drug with a ________ therapeutic...Ch. 12.L1 - Matching. Select the mode of action for each drug...Ch. 12.L1 - What was the purpose of giving postexposure...Ch. 12.L1 - What is a probable reason that tuberculosis...Ch. 12.L1 - Summarize the major problems with drug therapy as...Ch. 12.L1 - Using the diagram as a guide, briefly explain how...Ch. 12.L1 - Observe table 12.4 with regard to type of microbe...Ch. 12.L1 - Drugs are often given to patients before going...Ch. 12.L1 - Write an essay covering some of the main concerns...Ch. 12.L1 - Prob. 5WCCh. 12.L1 - Explain the kinds of tests that would...Ch. 12.L1 - Summarize the primary reasons that we find...Ch. 12.L2 - In 2015 the WHO surveyed 10,000 people on the...Ch. 12.L2 - Explain a simple test one could do to determine if...Ch. 12.L2 - Prob. 3CTCh. 12.L2 - You have been directed to take a sample from a...Ch. 12.L2 - From the results shown in figure 12.21, determine...Ch. 12.L2 - Explain why drugs that interfere with the...Ch. 12.L2 - In cases in which it is not possible to culture or...Ch. 12.L2 - Reviewing drug characteristics, choose an...Ch. 12.L2 - a. Using table 12.10 as a reference, find and...Ch. 12.L2 - For the following figures a-e, research the...
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- Is the following statement true or false and explain why: The therapeutic index is a measure of how well a drug acts to relieve a medical condition.arrow_forwardWhat impact does compounding have in pharmacy? Describe how compounding can improve medication compliance.arrow_forwardName at least three physical and chemical properties of drugs,also stating the effects of each property on the drug biological action.arrow_forward
- Describe the importance of tonicity in pharmaceutical preparation? Describe at your own wordsarrow_forwardExplain what is meant by a drug’s spectrum and how narrow- andbroad-spectrum drugs differ.arrow_forwardWhat are the Respective Structure Activity Relationship(SAR) of Sedative-hypnotic drugs? Please briefly explain at your own words.arrow_forward
- Considering the amount of drug information available in the internet, how will you know which one to consider? Give at least 5 factors that you need to consider. Explain each.arrow_forwardWhat is a synergistic drug interaction? Give Examplearrow_forwardBriefly describe about allosteric effect of a drug, explain allosteric effect with an examplearrow_forward
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