Explain the multifaceted role of interferons as first responders to viral infection: Identify important target ISGs. Discuss the general mechanisms by which interferon induced genes block virus replication.

explain how a viral infection results in elevated levels of inflammatory cytokines.

In what ways can cancer be both a cause and a symptom ofimmunodeficiency?

A 42-year-old woman comes to the physician for a follow-up examination after two separate Pap smears have shown dysplastic epithelial cells. Results of a molecular diagnostic test show DNA that encodes high-risk versions of the human papillomavirus E6 and E7 proteins. The viral E6 protein binds to the cellular p53 tumor suppressor gene, causing it to be degraded. Which of the following best describes the mechanism by which the E6 protein causes cervical cancer? (A) Arrests the cell cycle (B) Enhances tissue invasion and metastasis (C) Inhibits telomerase expression (D) Prevents apoptosis (E) Sustains angiogenesis