Campbell Essential Biology with Physiology (6th Edition)
6th Edition
ISBN: 9780134711751
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Chapter 12, Problem 9SQ
Summary Introduction
To determine: The correct order of steps of human gene therapy.
Introduction: Human gene therapy is used for the treatment of diseases but inserting new or altered gene in affected person. In some cases where the disease is caused by the presence of mutant allele, the therapy is done by replacing the mutant allele with normal allele.
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Make a list of ethical considerations for using gene therapy.
Discuss the process and give example on the following.
a. Aptamer Biosensors
b. CRISPR
c. Stem Cell Therapy
Write the advantages and disadvantages of applying such application in the DNA of an organism.
a. Drug delivery systems that are based on bacterial or viral host.
b. Producing genetically modified organisms to enhance food production.
c. Combining two or more genes in one organism to enhance its traits.
d. DNA manipulation of certain species to produce organs for harvesting.
Chapter 12 Solutions
Campbell Essential Biology with Physiology (6th Edition)
Ch. 12 - Suppose you wish to create a large batch of the...Ch. 12 - A carrier that moves DNA from one cell to another,...Ch. 12 - In making recombinant DNA, what is the benefit of...Ch. 12 - A paleontologist has recovered a bit of organic...Ch. 12 - Why do DNA fragments containing STR sites from...Ch. 12 - Prob. 6SQCh. 12 - Prob. 7SQCh. 12 - Name the steps of the whole-genome shotgun method.Ch. 12 - Prob. 9SQCh. 12 - Prob. 10IMT
Ch. 12 - Prob. 11IMTCh. 12 - Prob. 12IMTCh. 12 - Some scientists once joked that when the DNA...Ch. 12 - Prob. 14PSCh. 12 - Listed below are 4 of the 13 genome sites used to...Ch. 12 - In the not-too-distant future, gene therapy may be...Ch. 12 - Today, it is fairly easy to make transgenic plants...Ch. 12 - Prob. 18BSCh. 12 - Prob. 19BS
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the considerations for choice of a vector in gene therapy?arrow_forwardWhat's the best definition of gene therapy? a) The introduction of a non-mutated and functional gene into a patient's DNA. b) The delivery of a non-mutated and functional protein into a patient. c) The introduction of a non-mutated and functional gene into a patient's RNA. d) The delivery of drugs that encourage overexpression of a protein to compensate for a mutated protein.arrow_forwardWhat is the role of a vector in gene therapy?arrow_forward
- Below are some of the arguments about the use of transgenic organisms. From your own perspective, explain your answer in the questions in not more than 5 sentences. 1. If you are a farmer would you take the chance of growing crops that are pest resistant? Why or why not? 2. Considering the knowledge gained in genetic engineering, would you try to patronize GMO fruits and vegetables? Why or why not? 3. Is creating or altering genes of an organism a form of Blasphemy to the creator (God)? Why? 4. Is genetic engineering morally permissible or not?arrow_forwardIt has been suggested that it would make the study of human diseases easier if cloned transgenic animals were produced that carried faulty versions of human genes (e.g., the gene that causes cystic fibrosis). a. Why would such animals be useful in medical research? : b. What ethical questions are raised by the creation of such transgenic animals?arrow_forward2) Transgenic animal refers to an organism whose genome has been altered by the transfer of a gene or genes from another species or breed. Cows, pigs and goats had been modified especially for pharmaceutical purposes. Explain three (3) most used transfection technology for the creation of transgenic animals.arrow_forward
- For each situation, write the letter of the technique that would be most helpful; A. DNA editing A doctor wants to know if a patient has an inherited using CRISPR B. DNA replication using PCR C. DNA analysis through genetic testing D. DNA insertion 16. disorder. I A scientist needs many copies of a gene to conduct an 17. experiment. A genetic engineer wants to replace a defective copy of a gene with a functional copy in a chromosome. 18. into bacteria as a plasmid A medical researcher needs many copies of a protein 19. (insulin) to be produced to use in a medical treatment. A researcher crossed two purebred shrubs of the same species. One produces a fruit with a thin skin, and one produces a fruit with a thick skin. All of the plants resulting from the cross produce fruits with thick skins. Enter one letter in each blanks (19 & 20) to correctly complete the sentences. ninate Education TM, Inc.arrow_forwardA graduate student isolates two new retroviruses: Virus A and Virus B. To determine whether these viruses could cause cancer, the student infected human cells with each of the viruses and then transfered the infected cells to nude mice to see if the viruses would cause formation of tumors. The student was able to determine by PCR that both viruses are integrated into the genome of the host cells before transplanting cell in mice. The data for this assay are shown in the figure below. Explain how the mechanism of transduction may be different for these two viruses to yield the observed data (limit 4-5 sentences). Retrovirus Transformation Assay % Cells Cause Tumors 120 100 80 60 40 20 0 0 10 -Virus A -Virus B 30 20 Days Post Infection 40arrow_forwardThe CRISPR-Cas9 system can be used to: a. sequence a genome in living cells b. edit a gene in living cells and organisms c. diagnose sickle-cell anemia d. identify a specific gene e. detect gene expression under different conditionsarrow_forward
- A has been assembled by researchers and transplanted into a donor bacterial strain to study never before seen gene functions. Select one: a. Transgenic genome b. Recombinant DNA sequence c. Knockdown gene d. Synthetic genome o e. Recombinant plasmid Clear my choice is changing our Sequencing the human genome, the development of microarray technology, and understanding of complex diseases like cancer. They help us to observe the gene expression patterns in genetic disease by comparing the healthy tissue of individuals against the disease state of others. Select one: C a. Proteomics o b. Metagenomics MO C. Functional genomics d. Personal genomics O e. Developmental genomics Clear my choicearrow_forwardDefine the Problems with Gene Therapy Vectors ?arrow_forwardDescribe the ethical issues encompassing germ line gene therapy in 150 words.arrow_forward
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