Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 12, Problem 3NST
If a human nucleus is 10 μm in diameter, and it must hold as much as 2 m of DNA, which is complexed into nucleosomes that during full extension are 11 nm in diameter, what percentage of the volume of the nucleus is occupied by the genetic material?
HINT: This problem asks you to make some numerical calculations in order to see just how “filled” the eukaryotic nucleus is with a diploid amount of DNA. The key to its solution is the use of the formula V = (4/3)πr3, which calculates the volume of a sphere.
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If a human nucleus is 10 mm in diameter, and it must hold as much as 2 m of DNA, which is complexed into nucleosomes that during full extension are 11 nm in diameter, what percentage of the volume of the nucleus does the genetic material occupy?
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Chapter 12 Solutions
Concepts of Genetics (12th Edition)
Ch. 12 - In bacteriophages and bacteria, the DNA is almost...Ch. 12 - After salivary gland cells from Drosophila are...Ch. 12 - If a human nucleus is 10 m in diameter, and it...Ch. 12 - Roberts syndrome is a rare inherited disorder...Ch. 12 - Prob. 2CSCh. 12 - Roberts syndrome is a rare inherited disorder...Ch. 12 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 12 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 12 - Contrast the size of the single chromosome in...Ch. 12 - Describe the structure of giant polytene...
Ch. 12 - What genetic process is occurring in a puff of a...Ch. 12 - During what genetic process are lampbrush...Ch. 12 - Why might we predict that the organization of...Ch. 12 - Describe the sequence of research findings that...Ch. 12 - Describe the molecular composition and arrangement...Ch. 12 - Describe the transitions that occur as nucleosomes...Ch. 12 - Provide a comprehensive definition of...Ch. 12 - Mammals contain a diploid genome consisting of at...Ch. 12 - Assume that a viral DNA molecule is a 50-m-long...Ch. 12 - How many base pairs are in a molecule of phage T2...Ch. 12 - Examples of histone modifications are acetylation...Ch. 12 - Contrast the structure of SINE and LINE DNA...Ch. 12 - Variable number tandem repeats (VNTRs) are...Ch. 12 - It has been shown that infectious agents such as...Ch. 12 - Cancer can be defined as an abnormal proliferation...Ch. 12 - In a study of Drosophila, two normally active...Ch. 12 - Prob. 21ESPCh. 12 - An article entitled Nucleosome Positioning at the...Ch. 12 - Prob. 23ESPCh. 12 - Following is a diagram of the general structure of...Ch. 12 - Microsatellites are currently exploited as markers...Ch. 12 - At the end of the short arm of human chromosome 16...
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- Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatinarrow_forwardWhat difference exists between the compaction of chromosomes during metaphase versus interphase? Give at least one reason why this difference may be necessary.arrow_forwardConsider the figure beow, which depicts chromatin within the neucleus of a eukaryotic cell. nucleus O The letter A indicates regions of a single chromosome which are not expressed, and the letter B indicates regions of a single chromosome which are expressed. O Both answer choice A and answer choice B are correct. The letter A indicates regions of a single chromosome which are condensed and attached to the nuclear lamina, and the letter B indicates regions of a single chromosome which are partially decondensed. O Answer choices A, B and C are all correct. O The letter A represents repressed TADS, and the letter B represents active TADS.arrow_forward
- Consider the following DNA molecule (shown in the picture) and assume this is the DNA sequence of the entire chromosomes. list the amino acid sequences of the possible protein or proteins that could be produced from this DNA sequence what would be the DNA sequence of a sister chromatid generated from this chromosome sequence? (specify the 5' nd 3' ends)arrow_forwardWhich of the following statements regarding DNA synthesis at the ends of linear chromosomes is true?arrow_forwardAnswer the following four questions about DNA and chromosomes. (Hint: there may be slightly different numbers for these values-write the best one you know).What percentage of the human genome is made up of repetitive DNA? %What is the diameter of the chromatin fiber known as "beads on a string"? nmHow many histone proteins total assemble to make up a nucleosome? If a double stranded DNA has 22 percent adenine, what percent is guanine? %arrow_forward
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