Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 12, Problem 2CS
Summary Introduction
To describe: The ethical obligations experienced by the parents in allowing image circulation of their child in raising the awareness of the Roberts syndrome.
Introduction: The Roberts syndrome is an inherited disorder which characterizes with facial defects. Also, the person suffers from the shortening of limbs, abnormalities in the ankles and knees, and the presence of extra digits can also found.
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The dominant condition elliptocytosis causes red blood cells to become misshapen into oval-shaped cells. One of the genes responsible for the abnormal shape encodes the band 4.1 protein that together with ankyrin and other scaffold proteins creates and maintains the spherical concave shape of a normal red blood cell. The gene for band 4.1 protein, EPB41, is found on the p arm of chromosome 1. This is very close to the gene encoding the red blood cell Rhesus (Rh) blood type, either phenotype + (dominant) or - (recessive), with a recombination frequency of 2%. This means that 98% of the time alleles for these two genes are linked and are transmitted together.
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a. Manually, using a pencil, draw a cell in anaphase II from an organism in which 2n =
2 and each chromosome is metacentric.
b. Given that each G1 nucleus from this organism contains 16 picograms of DNA, how
many picograms of chromosomal DNA would you expect in the cell shown here?
Mitotic nondisjunction can occur, particularly in tumor cells.
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First, consider the daughter cell with the smaller number of chromosomes:
How many total chromosomes will this cell have?
How many X chromosomes will this cell have?
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How many total chromosomes will this cell have?
How many X chromosomes will this cell have?
Chapter 12 Solutions
Concepts of Genetics (12th Edition)
Ch. 12 - In bacteriophages and bacteria, the DNA is almost...Ch. 12 - After salivary gland cells from Drosophila are...Ch. 12 - If a human nucleus is 10 m in diameter, and it...Ch. 12 - Roberts syndrome is a rare inherited disorder...Ch. 12 - Prob. 2CSCh. 12 - Roberts syndrome is a rare inherited disorder...Ch. 12 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 12 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 12 - Contrast the size of the single chromosome in...Ch. 12 - Describe the structure of giant polytene...
Ch. 12 - What genetic process is occurring in a puff of a...Ch. 12 - During what genetic process are lampbrush...Ch. 12 - Why might we predict that the organization of...Ch. 12 - Describe the sequence of research findings that...Ch. 12 - Describe the molecular composition and arrangement...Ch. 12 - Describe the transitions that occur as nucleosomes...Ch. 12 - Provide a comprehensive definition of...Ch. 12 - Mammals contain a diploid genome consisting of at...Ch. 12 - Assume that a viral DNA molecule is a 50-m-long...Ch. 12 - How many base pairs are in a molecule of phage T2...Ch. 12 - Examples of histone modifications are acetylation...Ch. 12 - Contrast the structure of SINE and LINE DNA...Ch. 12 - Variable number tandem repeats (VNTRs) are...Ch. 12 - It has been shown that infectious agents such as...Ch. 12 - Cancer can be defined as an abnormal proliferation...Ch. 12 - In a study of Drosophila, two normally active...Ch. 12 - Prob. 21ESPCh. 12 - An article entitled Nucleosome Positioning at the...Ch. 12 - Prob. 23ESPCh. 12 - Following is a diagram of the general structure of...Ch. 12 - Microsatellites are currently exploited as markers...Ch. 12 - At the end of the short arm of human chromosome 16...
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- Humans and many other complex organisms are diploid, possessing two sets of genes, one inherited from the mother and one from the father. However, a number of eukaryotic organisms spend most of their life cycles in a haploid state. Many of these eukaryotes, such as Neurospora and yeast, still undergo meiosis and sexual reproduction, but most of the cells that make up the organism are haploid. Considering that haploid organisms are fully capable of sexual reproduction and generating genetic variation, why are most complex eukaryotes diploid? In other words, what might be the evolutionary advantage of existing in a diploid state instead of a haploid state? And why might a few organisms, such as Neurospora and yeast, exist as haploids?arrow_forwardFor below problem, consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis. You may wish to use a large piece of brown manila wrapping paper or a cut-up paper grocery bag for this project and to work in partnership with another student. We recommend cooperative learning as an efficacious way to develop the skills you will need for solving the problems presented throughout this text. Question: Assume that each gamete resulting from Problem 29 fuses, in fertilization, with a normal haploid gamete. What combinations will result? What percentage of zygotes will be diploid, containing one paternal and one maternal member of each chromosome pair?arrow_forwardconsider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap, etc.). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis. You may wish to use a large piece of brown manila wrapping paper or a large cut-up paper bag and work with another student as you deal with these problems. Such cooperative learning may be a useful approach as you solve problems throughout the text. Draw all possible combinations of chromatids during anaphase II in meiosis.arrow_forward
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