Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 10, Problem 4PDQ
Summary Introduction

To review:

The role of 15 N in the Meselson-Stahl experiment.

Introduction:

Meselson-Stahl experiment is given by Franklin Stahl and Matthew Meselson, which supports the Watson and Crick’s hypothesis that stated the DNA (deoxyribonucleic acid) replication was semiconservative in nature. This mode of replication is when the double helical molecule of DNA is replicated and each strand work as a template strand thereby conserving the content of the parental DNA strand.

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What is the role of ¹4N and ¹5N in Meselson-Stahl experiment? 15
The authors state: "Properties of the single mutants K557R, D591V and K617A, a double mutant, D591V/K617A, and a triple mutant, K557R/D591V/K617A, were evaluated to find an allosteric binding site for citrate." The numbers between the letters represent the residue number altered. The letter in front was the wild type and the letter afterwards is the mutant. How would the the triple mutations K557R and D591V and K617A alter the overall protein? O lower the # of charges, increase the pl O increase the # of charges, increase the pl O lower the # of charges, lower the pl O lower the # of charges, increase the pl O no change in the # of charges, increase the pl O no change in the # of charges, lower the pl
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY