Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 10, Problem 9PDQ
Summary Introduction
To review:
The characteristics of DNA (deoxyribonucleic acid) polymerase I raised the doubts that its function in vivo is the synthesis of DNA leading to complete replication.
Introduction:
DNA polymerase refers to the enzymes which synthesize the molecules of DNA from deoxyribonucleotides. Polymerase enzymes are necessary for the replication of DNA and generally work in pairs in order to make two copies of DNA strands from one single original molecule of DNA.
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Chapter 10 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 10 -
CASE STUDY | At loose ends
A researcher was...Ch. 10 - Prob. 2CSCh. 10 - Prob. 3CSCh. 10 - Prob. 4CSCh. 10 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 10 - Review the Chapter Concepts list on p. 180. These...Ch. 10 - Compare conservative, semiconservative, and...Ch. 10 - Prob. 4PDQCh. 10 - Predict the results of the experiment by Taylor,...Ch. 10 - Prob. 6PDQ
Ch. 10 - Prob. 7PDQCh. 10 - Prob. 8PDQCh. 10 - Prob. 9PDQCh. 10 - Prob. 10PDQCh. 10 - Prob. 11PDQCh. 10 - Prob. 12PDQCh. 10 - Prob. 13PDQCh. 10 -
14. Distinguish between (a) unidirectional and...Ch. 10 - Prob. 15PDQCh. 10 - Define and indicate the significance of (a)...Ch. 10 - Outline the current model for DNA synthesis.Ch. 10 - Why is DNA synthesis expected to be more complex...Ch. 10 - Prob. 19PDQCh. 10 - Several temperature-sensitive mutant strains of E....Ch. 10 - Prob. 21PDQCh. 10 - Prob. 22PDQ
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- Below is a diagram of DNA replication as currently believed to occur in E. coli. Arrows start from numbers and end at specific points. Answer the questions relating to the locations specified by the numbers (1) Which end (5' or 3') of the molecule is here? (2) Which enzyme is probably functioning here to deal with supercoils in the DNA? (3) Which enzyme is probably functioning here to unwind the DNA?arrow_forward“DNA polymerase plays a dual function during DNA replication” comment onstatement?arrow_forwardHow is DNA synthesis in the Polymerase Chain reaction similar to, or different from, DNA synthesis during genome replication in cells?arrow_forward
- Suggest a reason why it would be unlikely for replication to take place without unwinding the DNA helix.arrow_forwardWhat is The molecular mechanisms governing the initia-tion of DNA replication.arrow_forwardBriefly explain why DNA replication is semiconservative and discontinuous. Make sure to name the proteins involved in the synthesis of DNA, synthesis of RNA, the removal of RNA, and the sealing of the nicks.arrow_forward
- What is the function of Gyrase during DNA Replicationarrow_forwardBased on what you have learned with respect to various DNA repair pathways, decide the most appropriate pathway that would be used to repair the following types of DNA damage. Explain your reasoning. A change in the DNA sequence caused by a mistake made by DNA polymerase during replication In a fungal species, pyrimidine dimers induced as a result of UV exposure A double-stranded break that occurs during G1 and prevents completion of DNA replicationarrow_forwardIn terms of the new DNA strands that are generated, what are the differences between replication and conventional polymerase chain reaction?arrow_forward
- What is the role of telomerase in DNA replication.arrow_forwardWhich of the followings statements are true about DNA polymerase? 1.) It can only go in one direction, meaning the lagging strand can't be synthesized continuously. 2.) It cannot start a DNA strand from scratch, so another enzyme is needed to create "primers" as a starting point. 3.) It cannot copy epigenetic marks (such as methyl groups) on its own; these must be "copied" onto the daughter DNA strand by other enzymes after DNA replication. 4.) All of the abovearrow_forwardis replication unidirectional or bidirectional?arrow_forward
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