What is difference between the leading and lagging strands in DNA replication? Which? -Okazaki fragments are connected together with DNA polymerase. -The lagging strand has continuous DNA replication. -The leading strand produces short DNA fragments that get combined later. -The leading strand makes one, long piece of DNA. -The DNA polymerase on the lagging strand moves in the same direction as the replication fork.

Which of the following statements about DNA replication is INCORRECT? Select one: O a. DNA polymerase is the enzyme that adds nucleotides to the growing DNA strand. O b. DNA polymerase can only synthesize the new DNA strand in the 5' to 3' direction. O c. helicase is the enzyme which connects Okazaki fragments on the lagging strand. O d. the lagging strand has many primers. O e. the leading strand has only one primer.

What is the function of DNA helicase in DNA replication? to create an RNA primer to initiate DNA replication O to insert new bases during elongation, using the parent strand as a template O to anneal (splice) smaller fragments of DNA to create one continuous strand to create replication bubbles by unravelling the parental strands of DNA O all of the above

Medgie is creating his science fair project on DNA replication. His final display board shows the following. Human DNA Replication Steps Step 1 DNA unwinds in the nucleus Step 2 Complementary base pairs are deleted Step 3 DNA rewinds back together Step 4 The newly made DNA helix is placed in a cell formed in Mitosis According to Medgie's project, which of the following identifies and explains which of the steps is incorrect? O Step 4 is incorrect because not all human cells require DNA. O Step 3 is incorrect because the DNA remains unwound to be transcribed into RNA. Step 2 is incorrect because the complementary base pairs are used as a template, not deleted. Step 1 is incorrect because DNA doesn't unwind in the nucleus, instead it unwinds in the cytoplasm Previous

DNA polymerase occasionally incorporates the wrong nucleotide during DNA replication. If left unrepaired, the base-pair mismatch that results will lead to mutation in the next replication. As part of a template strand, the incorporated wrong base will direct the incorporation of a base complementary to itself, so the bases on both strands of the DNA at that position will now be different from what they were before the mismatch event. The MER-minus strain of yeast does not have a functional  mismatch excision repair system, but it has normal base excision repair and nucleotide excision repair systems. Which of the following statements is correct about differences in the mutation spectrum between MER-minus and wildtype yeast? More than one answer is correct. Options:   More point mutations will arise in MER-minus yeast.   Fewer point mutations will arise in MER-minus yeast as compared with wildtype.   Of the total point mutations that…

A drug that inhibits the DNAa protein is added to a culture of E. coli cells. What is the first step of DNA replication that will be impaired by this drug? Group of answer choices Keeping parent DNA strands separated Releasing tension generated by supercoiling Activating the origin of replication Making primers Forming phosphodiester bonds

Which of the following statements is/are TRUE for DNA Replication? Two daughter DNAs are formed, each one contains an old and new strands. When the (parent) DNA strands unwind, the 3'→ 5' strand is the leading strand while the 5'→3' strand is the lagging strand. Requires dATP, dTTP, dGTP, dCTP and Mg2+ The replisome is the biological machine responsible in replicating DNA.

Match the proteins with their function in DNA replication. unwinds DNA at replication fork forms covalent phosphodiester bonds to join DNA fragments remove primer and replace the RNA with DNA, also has 3'-> 5'exonuclease activity for proofreading synthesizes DNA by adding to the 3' end of the growing strand of DNA adds RNA primer uses an RNA template to facilitate extension of the telomeres in eukaryotes introduces a double-stranded break ahead of the replication fork and swivels the cleaved ends around the central axis to relieve the stress of helix unwinding helicase [Choose ] ✓ helicase telomerase DNA polymerase II DNA polymerase I DNA polymerase III DNA primase DNA ligase D DNA Gyrase (topoiso- merase) exonuclease