The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington’s disease. Using just the information on this pedigree, is Huntington’s disease caused by a dominant allele or recessive alleles?What are the genotypes of the grandparents (I-1 and I-2)?What are the genotypes of the parents (II-6 and II-7)?If the parents above have another child, what is the chance that they will be affected by the Hungtington’s disease allele?What are the genotypes of the unaffected children (III-8, 9, 10)?What is the chance that the unaffected children above will pass on a Huntington’s disease allele to their children?What is the genotype of the affected child (III-11)?What is the chance that the affected child above will pass on the Huntington’s disease allele to a child? ople are dllngton s uisease.1II34567III1234567891011© 2016 Pearson Education, Inc.

Name: The following pedigree shows the inheritance of Huntington’s disease,
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Description: The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing

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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington’s disease.

Using just the information on this pedigree, is Huntington’s disease caused by a dominant allele or recessive alleles?
What are the genotypes of the grandparents (I-1 and I-2)?
What are the genotypes of the parents (II-6 and II-7)?
If the parents above have another child, what is the chance that they will be affected by the Hungtington’s disease allele?
What are the genotypes of the unaffected children (III-8, 9, 10)?
What is the chance that the unaffected children above will pass on a Huntington’s disease allele to their children?
What is the genotype of the affected child (III-11)?
What is the chance that the affected child above will pass on the Huntington’s disease allele to a child?

ople are dll
ngton s uisease.
1
II
3
4
5
6
7
III
1
2
3
4
5
6
7
8
9
10
11
© 2016 Pearson Education, Inc.

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