Is the inheritance pattern indicated by the shaded symbols in this pedigree consistent with the inheritance pattern of a Y-linked characteristic? Select one: O a. Yes O b. No

This pedigree (below) shows inheritance of a genetic disorder in a family. Assume the trait is rare. What is the mode of inheritance for this trait? [Select] You know this because that mode of inheritance is characterized by: [ Select] • An affected male parent passes the allele to [Select] and [Select] individuals who have the allele express it and and [Select] of his daughters. • An affected female parent passes the allele to [Select] of her daughters. ㅇㅁㅇㅁ î то ◆ of his sons of her so ?

Joseph is heterozygous for the traits F (dominant to f) and B (dominant to b)and his genes are in cis, and these locuses are on the same chromosome and separated by 30 map units. Sara is also heterozygous for these traits but here genes are in trans. Calculate how likely it would be to observe an individual who is homozygous dominant for the genes F and B. Be sure to show your work for full credit.

One family is shown in both pedigrees below. Each pedigree focuses on a different monogenic, fully penetrant phenotype. Shaded individuals affected by Phenotype 1: 3 Shaded individuals affected by Phenotype 2: a. Phenotype 1: Which modes of inheritance can be ruled out, base don't this pedigree? For each mode of inheritance listed below, either state that it is not ruled out, or describe a detail of the pedigree that allows you to rule it out. Autosomal recessive Autosomal dominant X-linked recessive X-linked dominant Y-linked b. Phenotype 2: Which modes of inheritance can be ruled out, base don't this pedigree? For each mode of inheritance listed below, either state that it is not ruled out, or describe a detail of the pedigree that allows you to rule it out. Autosomal recessive Autosomal dominant X-linked recessive X-linked dominant