Match the gene on the left with the gene category on the right.                                                             ERBB2                                                             E-cadherin                                                             BRCA1                                                             Cdk4 A. oncogene B. proto-oncogene C. low expression in invasive cells D. tumor suppressor gene

Q: The normal function of the Rb protein is toa. act as a brake on cell division.b. produce…

A: BASIC INFORMATION  CELL DIVISION  It is necessary for all the cells In this the parent cell divides…

Q: The drug pump activity of Cancer stem cells can be explained by the overexpression of: a. Mdr1 b.…

A: Cancer is the state of uncontrolled cell division.

Q: Which of the following describes an oncogene Group of answer choices A. a gene that stimulates cell…

A: Cancer is caused by changes in the DNA and is called genetic changes. Cancer is the growth of the…

Q: a way in which proto-oncogenes can change to become genes that induce cancer?

A: A proto-oncogene is a normal gene that can turn into an oncogene due to mutations or increased…

Q: Defects in this gene have been associated with metastasis in pancreatic cancer. Select one: O a. APC…

A: Answer : Option "G" is correct - BRCA1

Q: Why are dominant mutations in proto-oncogenes generally not inherited? A. Inherited mutations in…

A: Cancer is a condition that manifests as the unchecked growth of a collection of abnormal cells that…

Q: Which of the following statements are correct about cancer drug resistance (select all that apply)?

A: Cancer drug resistance is the acquired after treatment effects that many of the Cancer Patients…

Q: Overexpression of Mdr1 in cancer cells causes the cells to be a. Apoptotic b. Susceptible to…

A: MDR is a P-glycoprotein family gene having MDR1 & MDR2 members. MDR1 gene expresses and forms…

Q: A mutated gene that codes for an altered version of Cdk that is active in the absence of cyclin is…

A: Cyclins drive the occasions of the phone cycle by collaborating with a group of chemicals called the…

Q: Developing B cells that fail to make productive D to J heavy-chain rearrangements on both homologous…

A: B cells get matured in the bone marrow or in the lymph node. Mature B cells express antibodies on…

Q: These genes are involved in normal cell growth and division, but if mutated, could become more…

A: Oncogenes are tumour-causing genes. They are mutated and abnormal that leading to uncontrolled cell…

Q: Which of the following statements are true about the rate of mutation in tumor cells (select all…

A: Chromosome rearrangements, which occur at high rates due to aneuploidy, an aberrant chromosome…

Q: ene therapy approaches have been studied for cancer gene therapy. These approaches include? (select…

A: Cancer Cancer is a serious disease marked by an abnormal and uncontrolled cell division of cells…

Q: Which of the following classes of oncogenes would likely be druggable with a small molecule (select…

A: Oncogenes are genes that have the potential to cause cancer. They can be found in normal cells and…

Q: 39. HIV could be used to cure Kaposi’s sarcoma by  a. causing the cells to express exogenous surface…

A: HIV is stands for human immunodeficiency virus. This is type of retroviral infection transfer…

Q: IGF-I acts to: a.      increase blood glucose b.      stimulate lipolysis c.      stimulate cellular…

A: The human growth hormone (HGH) is peptide hormone that is secreted by the anterior pituitary gland’s…

Q: Which of the following mutations is likely to be associated with development of cancer? Loss of SMO…

A: The cells are basic structural and functional units of life. The human body contains many types of…

Q: If a is inactive, a cell may become cancerous. Ca. proto-oncogene b. tumor suppressor gene Cc.…

A: Cancer is the group of diseases. It involves the uncontrolled division of normal cells in the body.…

Q: graduate student wants to isolate cells from a patient and grow them perpetually in culture to study…

A: The correct answers are as follows- A. Telomerase C. MDM2  A graduate student wants to isolate cells…

Q: Cells require growth factors from other cells to proliferate   B. Growth Factors must enter cell…

A: Growth factor signalling is a cell signalling pathway that regulates the growth and development of…

Q: 1. For each of the following genes, categorize them as a tumor suppressor gene or a protooncogene.…

A: Bcl-2 gene is a protooncogene.The Bcl-2 can act as a barrier to apoptosis and and facilitate the…

Q: Please help me with the genomics/developmental biology question below: Matching A. Proto-oncogenes…

A: The cell cycle is a highly regulated process with different checkpoint ensuring correct events has…

Q: Tumor Suppressor Genes are often called as gatekeepers because: a. They signify their involvement…

A: The correct option is a i.e.They signify their involvement in governing the dynamics of cell…

Q: Mutations to proto-oncogenes act toa. increase cell division. c. repress oncogenes.b. increase DNA…

A: Cancer-critical genes are categorized into classes; Proto-oncogenes and Tumor-suppressor genes. The…

Q: Why are cancers considered to be clonal in origin? O A They are considered clonal in origin because…

A: Cancer- It is a group of diseases that is commonly related to the uncontrolled proliferation of…

Q: A cell in this stage of cancer no longer makes the set of proteins that is was originally instructed…

A: There are 3 pre cancerous stages -  1) hyperplasia  2) dysplasia  3) carcinoma in situ  Hyperplasia-…

Q: Which of the following statements are correct about viruses and cancer (select all that appy)?   A.…

A: Viruses are not considered living beings because they lack life-like properties such "as the…

Q: O The RB gene is likely hypomethylated in this individual O This individual is at much higher risk…

A: Retinoblastoma is an ocular malignancy occurring during childhood, which can affect both eyes and is…

Q: VHL is a tumor suppressor because     a. it causes cancer cells to become hypoxic     b. it…

A: Tumor is a mass or lump that results from the abnormal growth of cells in the body. A tumor…

Q: You are looking at the results of a western blot from the lysates of cells harvested from a…

A: When you observe an increased expression of INK4-p16 in the lysates of cells harvested from a…

Q: Match the following statements to the type of gene they describe. ✓Encode proteins that promote cell…

A: Tumor supressor genes are those whose deletion or under expression may cause cancer. They include…

Q: An individual can inherit a gene in which expression has been altered by an ________ change with no…

A:

Q: Which of the following accurately compares tumor suppressor genes and proto-oncogenes? A. Both…

A: Tumor suppressor genes and proto-oncogenes are both types of genes that play important roles in…

Q: Hypermethylation is thought to contribute to cancer by a. inhibiting DNA replication. b. inhibiting…

A: DNA methylation is one of the intensely studied epigenetic modifications in mammals. The regulation…

Q: In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an…

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Q: 1. Match each of the terms in the left column to the bestfitting phrase from the right column.a.…

A: The terms given in the left column are related to the genetic material of an organism. Genetic…

Q: Which of the following associated with cancer development would you expect to be tumor promoters and…

A: Introduction: A chemical that can increase the risk of cancer by a secondary mechanism unrelated to…

Q: Cancer Cells need A.I.R in order to survive and proliferate. What does this stand for?   a.…

A: Oncogene activation requires genetic alterations in cellular protooncogenes. The result of these…

Q: Retroviruses can cause cancer, along with some viruses with DNA genomes. For example, herpes…

A: Retroviruses can cause cancer. For example, herpes papillomavirus (HPV) causes cervical cancer. The…

Q: Define the following terms: a. cell transformation b. oncogene c. apoptosis d. early response gene…

A: Gene regulation is the mechanism that acts to induce or repress the expression of the gene.that…

Q: A tumor suppressor gene regulates the cell cycle; an example is

A: The tumor suppressor genes are anti-oncogenes that prevent the uncontrolled growth of the cells by…

Q: Which of the following would most likely promote necrosis?

A: The death of cells or any tissue of body is called as necrosis. Whenever tissue is not getting…